Protein : Qrob_P0551080.2 Q. robur

Protein Identifier  ? Qrob_P0551080.2 Organism . Name  Quercus robur
Score  35.0 Score Type  egn
Protein Description  (M=3) K01191 - alpha-mannosidase [EC:3.2.1.24] Code Enzyme  EC:3.2.1.24
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1008  
Kegg Orthology  K01191

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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0008270 zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.
GO:0030246 carbohydrate binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:0006013 mannose metabolic process The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
GO:0015923 mannosidase activity Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.
GO:0004559 alpha-mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.

43 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cit:102623299 2 1007 + 1006 Gaps:7 99.61 1017 81.44 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|pper:PRUPE_ppa000707mg 18 1005 + 988 Gaps:7 96.88 1027 82.71 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_046753 1 1007 + 1007 Gaps:8 100.00 1015 81.77 0.0 Glycosyl hydrolase family 38 protein
blastp_kegg lcl|pmum:103330437 18 1007 + 990 Gaps:7 97.46 1023 83.05 0.0 lysosomal alpha-mannosidase
blastp_kegg lcl|fve:101310733 18 1007 + 990 Gaps:9 98.23 1015 80.94 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|cam:101507790 5 1003 + 999 Gaps:7 98.34 1023 79.32 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|mdm:103442078 2 1007 + 1006 Gaps:13 99.41 1021 80.20 0.0 lysosomal alpha-mannosidase
blastp_kegg lcl|rcu:RCOM_1445250 1 1006 + 1006 Gaps:8 99.80 1016 79.39 0.0 lysosomal alpha-mannosidase putative (EC:3.2.1.24)
blastp_kegg lcl|mtr:MTR_7g084040 4 1003 + 1000 Gaps:6 98.43 1022 79.13 0.0 Lysosomal alpha-mannosidase
blastp_kegg lcl|vvi:100266854 1 1007 + 1007 Gaps:6 98.64 1027 80.06 0.0 lysosomal alpha-mannosidase-like
blastp_pdb 1o7d_A 23 317 + 295 Gaps:4 99.66 298 50.51 5e-97 mol:protein length:298 LYSOSOMAL ALPHA-MANNOSIDASE
blastp_pdb 1hxk_A 22 821 + 800 Gaps:117 80.49 1015 29.38 2e-83 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 1hww_A 22 821 + 800 Gaps:117 80.49 1015 29.38 2e-83 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 1hty_A 22 821 + 800 Gaps:117 80.49 1015 29.38 2e-83 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 3eju_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejt_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejs_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejr_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejq_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejp_A 22 821 + 800 Gaps:117 78.18 1045 29.38 4e-83 mol:protein length:1045 Alpha-mannosidase 2
blastp_uniprot_sprot sp|Q8VHC8|MA2B1_CAVPO 23 1001 + 979 Gaps:62 94.84 1007 42.41 0.0 Lysosomal alpha-mannosidase OS Cavia porcellus GN MAN2B1 PE 1 SV 1
blastp_uniprot_sprot sp|Q29451|MA2B1_BOVIN 9 1001 + 993 Gaps:69 95.90 999 42.17 0.0 Lysosomal alpha-mannosidase OS Bos taurus GN MAN2B1 PE 1 SV 4
blastp_uniprot_sprot sp|Q60HE9|MA2B1_MACFA 23 1006 + 984 Gaps:57 94.96 1012 42.14 0.0 Lysosomal alpha-mannosidase OS Macaca fascicularis GN MAN2B1 PE 2 SV 1
blastp_uniprot_sprot sp|O00754|MA2B1_HUMAN 23 1006 + 984 Gaps:57 95.05 1011 41.94 0.0 Lysosomal alpha-mannosidase OS Homo sapiens GN MAN2B1 PE 1 SV 3
blastp_uniprot_sprot sp|O46432|MA2B1_FELCA 23 1001 + 979 Gaps:59 94.54 1007 42.33 0.0 Lysosomal alpha-mannosidase OS Felis catus GN MAN2B1 PE 2 SV 1
blastp_uniprot_sprot sp|O09159|MA2B1_MOUSE 7 1001 + 995 Gaps:63 95.95 1013 40.74 0.0 Lysosomal alpha-mannosidase OS Mus musculus GN Man2b1 PE 2 SV 4
blastp_uniprot_sprot sp|P34098|MANA_DICDI 35 997 + 963 Gaps:79 95.64 1010 40.99 0.0 Lysosomal alpha-mannosidase OS Dictyostelium discoideum GN manA PE 1 SV 2
blastp_uniprot_sprot sp|P27046|MA2A1_MOUSE 33 817 + 785 Gaps:127 70.61 1150 29.93 1e-93 Alpha-mannosidase 2 OS Mus musculus GN Man2a1 PE 1 SV 2
blastp_uniprot_sprot sp|Q16706|MA2A1_HUMAN 33 816 + 784 Gaps:151 70.72 1144 31.40 4e-91 Alpha-mannosidase 2 OS Homo sapiens GN MAN2A1 PE 1 SV 2
blastp_uniprot_sprot sp|Q8BRK9|MA2A2_MOUSE 33 819 + 787 Gaps:105 71.18 1152 28.78 9e-88 Alpha-mannosidase 2x OS Mus musculus GN Man2a2 PE 2 SV 2

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 3 14 12 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Gene3D 452 597 146 G3DSA:2.60.40.1180 none none IPR013780
Pfam 36 347 312 PF01074 none Glycosyl hydrolases family 38 N-terminal domain IPR000602
Gene3D 880 1000 121 G3DSA:2.60.40.1360 none none none
Pfam 479 996 518 PF07748 none Glycosyl hydrolases family 38 C-terminal domain IPR011682
Gene3D 598 857 260 G3DSA:2.70.98.30 none none none
PANTHER 1 1004 1004 PTHR11607:SF18 none none none
Gene3D 12 349 338 G3DSA:3.20.110.10 none none IPR027291
Phobius 15 19 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
SUPERFAMILY 351 444 94 SSF88688 none none IPR028995
SUPERFAMILY 24 350 327 SSF88713 none none IPR011330
Phobius 1 2 2 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Pfam 353 426 74 PF09261 none Alpha mannosidase, middle domain IPR015341
Phobius 20 1007 988 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 1 1004 1004 PTHR11607 none none none
Gene3D 351 449 99 G3DSA:1.20.1270.50 none none IPR015341
SUPERFAMILY 448 999 552 SSF74650 none none IPR011013
Phobius 1 19 19 SIGNAL_PEPTIDE none Signal peptide region none
SMART 352 426 75 SM00872 none Alpha mannosidase, middle domain IPR015341

3 Localization

Analysis Start End Length
SignalP_GRAM_POSITIVE 1 22 21
SignalP_EUK 1 19 18
SignalP_GRAM_NEGATIVE 1 22 21

0 Qtllist

0 Targeting