Protein : Qrob_P0504250.2 Q. robur
Protein Identifier  ? Qrob_P0504250.2 Organism . Name  Quercus robur
Score  96.0 Score Type  egn
Protein Description  (M=2) K13034 - L-3-cyanoalanine synthase/ cysteine synthase [EC:2.5.1.47 4.4.1.9] Code Enzyme  EC:2.5.1.47
Gene Prediction Quality  validated Protein length 

Sequence

Length: 329  
Kegg Orthology  K13034
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0 Synonyms

7 GO Terms

Identifier Name Description
GO:0030170 pyridoxal phosphate binding Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
GO:0005739 mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GO:0006535 cysteine biosynthetic process from serine The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.
GO:0004124 cysteine synthase activity Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
GO:0006520 cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0019499 cyanide metabolic process The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.
GO:0050017 L-3-cyanoalanine synthase activity Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.

44 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|mtr:MTR_7g078070 15 328 + 314 none 82.63 380 92.68 0.0 Cysteine synthase
blastp_kegg lcl|pvu:PHAVU_008G061100g 15 328 + 314 none 82.63 380 91.40 0.0 hypothetical protein
blastp_kegg lcl|gmx:100806420 15 328 + 314 none 84.18 373 91.08 0.0 l-3-cyanoalanine synthase 1 mitochondrial-like
blastp_kegg lcl|gmx:100101899 15 328 + 314 none 84.41 372 90.76 0.0 OAS-TL3 OAS-TL3 cysteine synthase
blastp_kegg lcl|cmo:103497706 15 328 + 314 none 82.85 379 91.40 0.0 bifunctional L-3-cyanoalanine synthase/cysteine synthase 1 mitochondrial
blastp_kegg lcl|csv:101220896 15 328 + 314 none 83.73 375 91.08 0.0 l-3-cyanoalanine synthase 2 mitochondrial-like
blastp_kegg lcl|rcu:RCOM_1615850 15 328 + 314 none 88.45 355 90.13 0.0 cysteine synthase putative (EC:2.5.1.47)
blastp_kegg lcl|cam:101512608 15 328 + 314 none 81.35 386 91.40 0.0 l-3-cyanoalanine synthase 1 mitochondrial-like
blastp_kegg lcl|tcc:TCM_005308 15 328 + 314 Gaps:14 85.42 384 88.72 0.0 Cysteine synthase C1
blastp_kegg lcl|sly:101253940 15 328 + 314 none 89.46 351 89.17 0.0 bifunctional L-3-cyanoalanine synthase/cysteine synthase 1 mitochondrial-like
blastp_pdb 4aec_B 12 324 + 313 none 72.79 430 59.74 4e-132 mol:protein length:430 CYSTEINE SYNTHASE MITOCHONDRIAL
blastp_pdb 4aec_A 12 324 + 313 none 72.79 430 59.74 4e-132 mol:protein length:430 CYSTEINE SYNTHASE MITOCHONDRIAL
blastp_pdb 2isq_A 15 322 + 308 none 96.25 320 61.69 2e-131 mol:protein length:320 Cysteine synthase
blastp_pdb 1z7w_A 15 322 + 308 none 95.65 322 61.69 2e-131 mol:protein length:322 Cysteine synthase
blastp_pdb 1z7y_A 15 322 + 308 none 95.65 322 61.36 1e-130 mol:protein length:322 Cysteine synthase
blastp_pdb 2q3d_A 15 315 + 301 Gaps:1 95.85 313 53.00 6e-101 mol:protein length:313 Cysteine synthase A
blastp_pdb 2q3c_A 15 315 + 301 Gaps:1 95.85 313 53.00 6e-101 mol:protein length:313 Cysteine synthase A
blastp_pdb 2q3b_A 15 315 + 301 Gaps:1 95.85 313 53.00 6e-101 mol:protein length:313 Cysteine synthase A
blastp_pdb 3rr2_A 12 315 + 304 Gaps:1 96.50 314 53.14 2e-100 mol:protein length:314 Cysteine synthase
blastp_pdb 4air_B 15 322 + 308 Gaps:1 86.72 354 48.21 4e-91 mol:protein length:354 CYSTEINE SYNTHASE
blastp_uniprot_sprot sp|Q76MX2|CAS1_SOLTU 15 328 + 314 none 89.46 351 87.90 0.0 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 1 mitochondrial OS Solanum tuberosum GN PCAS-1 PE 1 SV 1
blastp_uniprot_sprot sp|Q1KLZ1|CAS2_MALDO 15 328 + 314 none 83.73 375 88.22 0.0 L-3-cyanoalanine synthase 2 mitochondrial OS Malus domestica GN CAS2 PE 1 SV 1
blastp_uniprot_sprot sp|Q1KLZ2|CAS1_MALDO 15 328 + 314 none 83.51 376 87.26 0.0 L-3-cyanoalanine synthase 1 mitochondrial OS Malus domestica GN CAS1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9FS29|CAS2_SOLTU 15 328 + 314 none 90.49 347 85.99 0.0 Bifunctional L-3-cyanoalanine synthase/cysteine synthase 2 mitochondrial OS Solanum tuberosum GN PCAS-2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9S757|CYSC1_ARATH 16 328 + 313 none 85.05 368 84.35 0.0 Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1 mitochondrial OS Arabidopsis thaliana GN CYSC1 PE 1 SV 1
blastp_uniprot_sprot sp|Q43153|CYSC_SPIOL 3 328 + 326 none 88.59 368 81.90 0.0 Bifunctional L-3-cyanoalanine synthase/cysteine synthase mitochondrial OS Spinacia oleracea GN CYSC PE 1 SV 1
blastp_uniprot_sprot sp|P32260|CYSKP_SPIOL 15 324 + 310 none 80.94 383 63.55 3e-138 Cysteine synthase chloroplastic/chromoplastic OS Spinacia oleracea GN CYSK PE 1 SV 2
blastp_uniprot_sprot sp|O81155|CYSKP_SOLTU 15 324 + 310 none 80.31 386 62.58 2e-137 Cysteine synthase chloroplastic/chromoplastic OS Solanum tuberosum PE 2 SV 1
blastp_uniprot_sprot sp|Q00834|CYSK_SPIOL 7 322 + 316 none 97.23 325 62.34 7e-135 Cysteine synthase OS Spinacia oleracea PE 1 SV 1
blastp_uniprot_sprot sp|Q9XEA8|CYSK2_ORYSJ 16 322 + 307 none 94.46 325 63.19 4e-133 Cysteine synthase OS Oryza sativa subsp. japonica GN RCS3 PE 2 SV 1

15 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 16 323 308 PTHR10314 none none none
Phobius 1 3 3 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
PANTHER 16 323 308 PTHR10314:SF80 "KEGG:00460+4.4.1.9";signature_desc=BIFUNCTIONAL L-3-CYANOALANINE SYNTHASE/CYSTEINE SYNTHASE C1, MITOCHONDRIAL (PTHR10314:SF80) none IPR031111
ProSitePatterns 39 57 19 PS00901 none Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. IPR001216
Phobius 12 16 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Pfam 15 300 286 PF00291 none Pyridoxal-phosphate dependent enzyme IPR001926
ProSitePatterns 41 54 14 PS00165 none Serine/threonine dehydratases pyridoxal-phosphate attachment site. IPR000634
Phobius 1 16 16 SIGNAL_PEPTIDE none Signal peptide region none
TIGRFAM 15 312 298 TIGR01139 "KEGG:00270+2.5.1.47","KEGG:00920+2.5.1.47","MetaCyc:PWY-6936","UniPathway:UPA00136" cysK: cysteine synthase A IPR005859
Gene3D 143 314 172 G3DSA:3.40.50.1100 none none none
Gene3D 44 142 99 G3DSA:3.40.50.1100 none none none
Phobius 4 11 8 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
TIGRFAM 15 312 298 TIGR01136 "KEGG:00270+2.5.1.47","KEGG:00920+2.5.1.47","MetaCyc:PWY-6936","UniPathway:UPA00136" cysKM: cysteine synthase IPR005856
SUPERFAMILY 13 316 304 SSF53686 none none IPR001926
Phobius 17 328 312 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran1_2004_QTL4_peak_Bud_burst_3P Qrob_Chr04 4 s_1AHUWN_1101 s_1BRNG7_1618 30,55 0 47,55 lod 2,8 7,4
Bourran2_2002_QTL10_peak_Bud_burst_A4 Qrob_Chr04 4 s_1B59MJ_737 s_1BGLSD_999 15,86 0 41,66 lod 2,8 4
Bourran1_2000_QTL3_peak_Bud_burst_3P Qrob_Chr04 4 s_1A6DJQ_418 s_1A1PEC_1268 23,09 9,09 44,09 lod 2,3 6,8
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL7_d13Cf Qrob_Chr04 4 s_1B91MJ_705 s_1AHIKX_640 33.92 12,11 48,31 lod 6.1865 0.023

0 Targeting