Protein : Qrob_P0486650.2 Q. robur
Protein Identifier  ? Qrob_P0486650.2 Organism . Name  Quercus robur
Score  98.2 Score Type  egn
Protein Description  (M=4) K08150 - MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 219  
Kegg Orthology  K08150
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|fve:101294438 2 217 + 216 none 36.73 588 74.54 1e-111 inositol transporter 4-like
blastp_kegg lcl|sot:102593035 2 216 + 215 none 37.26 577 74.88 9e-110 inositol transporter 4-like
blastp_kegg lcl|pmum:103326971 2 217 + 216 none 38.03 568 76.85 2e-109 inositol transporter 4-like
blastp_kegg lcl|mdm:103446801 2 217 + 216 none 37.44 577 77.31 8e-109 inositol transporter 4-like
blastp_kegg lcl|mdm:103408752 2 217 + 216 none 37.44 577 77.31 9e-109 inositol transporter 4-like
blastp_kegg lcl|sly:101246700 1 217 + 217 none 37.41 580 70.97 1e-108 inositol transporter 4-like
blastp_kegg lcl|pxb:103942670 2 217 + 216 none 37.50 576 77.31 2e-108 inositol transporter 4-like
blastp_kegg lcl|tcc:TCM_030370 1 217 + 217 none 37.67 576 71.43 3e-108 Inositol transporter 4
blastp_kegg lcl|pxb:103936814 1 217 + 217 none 37.54 578 77.42 4e-108 inositol transporter 4-like
blastp_kegg lcl|pxb:103963755 1 217 + 217 none 37.54 578 77.42 4e-108 inositol transporter 4
blastp_uniprot_sprot sp|O23492|INT4_ARATH 1 217 + 217 none 37.29 582 71.89 1e-101 Inositol transporter 4 OS Arabidopsis thaliana GN INT4 PE 1 SV 1
blastp_uniprot_sprot sp|Q9C757|INT2_ARATH 2 217 + 216 Gaps:2 37.59 580 70.18 7e-98 Probable inositol transporter 2 OS Arabidopsis thaliana GN INT2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9ZQP6|INT3_ARATH 25 217 + 193 none 33.28 580 68.39 1e-90 Probable inositol transporter 3 OS Arabidopsis thaliana GN INT3 PE 2 SV 1
blastp_uniprot_sprot sp|Q8VZR6|INT1_ARATH 14 217 + 204 none 40.08 509 59.80 3e-72 Inositol transporter 1 OS Arabidopsis thaliana GN INT1 PE 1 SV 1
blastp_uniprot_sprot sp|Q96QE2|MYCT_HUMAN 23 217 + 195 Gaps:5 29.94 648 44.33 6e-44 Proton myo-inositol cotransporter OS Homo sapiens GN SLC2A13 PE 1 SV 3
blastp_uniprot_sprot sp|C0SPB2|YWTG_BACSU 36 217 + 182 Gaps:4 38.95 457 43.82 5e-42 Putative metabolite transport protein YwtG OS Bacillus subtilis (strain 168) GN ywtG PE 3 SV 1
blastp_uniprot_sprot sp|P87110|ITR2_SCHPO 13 217 + 205 Gaps:1 36.62 557 40.69 2e-41 Myo-inositol transporter 2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN itr2 PE 2 SV 1
blastp_uniprot_sprot sp|Q01440|GTR1_LEIDO 32 217 + 186 Gaps:5 34.55 547 41.27 4e-41 Membrane transporter D1 OS Leishmania donovani PE 3 SV 1
blastp_uniprot_sprot sp|Q921A2|MYCT_RAT 23 217 + 195 Gaps:5 30.46 637 44.33 4e-40 Proton myo-inositol cotransporter OS Rattus norvegicus GN Slc2a13 PE 2 SV 2
blastp_uniprot_sprot sp|Q3UHK1|MYCT_MOUSE 23 217 + 195 Gaps:5 30.46 637 44.33 5e-40 Proton myo-inositol cotransporter OS Mus musculus GN Slc2a13 PE 2 SV 2
rpsblast_cdd gnl|CDD|200987 30 217 + 188 Gaps:12 44.54 449 37.50 1e-37 pfam00083 Sugar_tr Sugar (and other) transporter.
rpsblast_cdd gnl|CDD|162084 24 217 + 194 Gaps:10 42.41 481 38.24 3e-37 TIGR00879 SP MFS transporter sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083).
rpsblast_cdd gnl|CDD|182225 26 214 + 189 Gaps:24 44.47 479 35.68 4e-34 PRK10077 xylE D-xylose transporter XylE Provisional.
rpsblast_cdd gnl|CDD|119392 34 208 + 175 Gaps:4 48.58 352 27.49 6e-14 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
rpsblast_cdd gnl|CDD|162097 62 217 + 156 Gaps:12 30.10 505 26.32 1e-11 TIGR00898 2A0119 cation transport protein.
rpsblast_cdd gnl|CDD|179668 14 213 + 200 Gaps:34 38.31 496 30.53 2e-11 PRK03893 PRK03893 putative sialic acid transporter Provisional.
rpsblast_cdd gnl|CDD|183191 83 214 + 132 Gaps:8 32.51 406 31.06 6e-09 PRK11551 PRK11551 putative 3-hydroxyphenylpropionic transporter MhpT Provisional.
rpsblast_cdd gnl|CDD|162092 32 217 + 186 Gaps:12 45.43 405 25.00 7e-09 TIGR00891 2A0112 putative sialic acid transporter.
rpsblast_cdd gnl|CDD|162095 24 217 + 194 Gaps:5 47.99 398 26.70 7e-08 TIGR00895 2A0115 benzoate transport.
rpsblast_cdd gnl|CDD|191813 71 207 + 137 Gaps:1 39.31 346 22.79 5e-07 pfam07690 MFS_1 Major Facilitator Superfamily.

22 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSitePatterns 129 154 26 PS00217 none Sugar transport proteins signature 2. IPR005829
Phobius 146 156 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
SUPERFAMILY 20 213 194 SSF103473 none none IPR020846
Gene3D 34 213 180 G3DSA:1.20.1250.20 none none none
Phobius 120 124 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Pfam 31 216 186 PF00083 none Sugar (and other) transporter IPR005828
PANTHER 1 217 217 PTHR24063 none none none
Phobius 208 218 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PRINTS 124 143 20 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 38 48 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
Phobius 125 145 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 67 89 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 1 217 217 PTHR24063:SF299 none none none
Phobius 188 207 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 56 66 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
ProSiteProfiles 30 218 189 PS50850 none Major facilitator superfamily (MFS) profile. IPR020846
Phobius 26 55 30 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 177 187 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 90 100 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 157 176 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 25 25 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 101 119 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

6 Localization

Analysis Start End Length
TMHMM 155 177 22
TMHMM 67 89 22
TMHMM 33 55 22
TMHMM 123 145 22
TMHMM 184 206 22
TMHMM 99 116 17

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_vSeqBC_3P Qrob_Chr10 10 s_1A6CK6_610 v_7092_29 4,28 0 23,27 lod 2,8619 7
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran1_2004_QTL4_peak_Bud_burst_3P Qrob_Chr04 4 s_1AHUWN_1101 s_1BRNG7_1618 30,55 0 47,55 lod 2,8 7,4
Bourran2_2002_QTL10_peak_Bud_burst_A4 Qrob_Chr04 4 s_1B59MJ_737 s_1BGLSD_999 15,86 0 41,66 lod 2,8 4

0 Targeting