Protein : Qrob_P0474090.2 Q. robur
Protein Identifier  ? Qrob_P0474090.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=3) K12817 - pre-mRNA-splicing factor 18 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 382  
Kegg Orthology  K12817
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0005681 spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
GO:0008380 RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

24 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100798833 1 380 + 380 Gaps:24 95.88 413 73.99 0.0 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|gmx:100785799 1 380 + 380 Gaps:23 96.11 411 74.18 0.0 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|tcc:TCM_004356 1 380 + 380 Gaps:28 96.39 415 74.50 0.0 Splicing factor Prp18 family protein isoform 1
blastp_kegg lcl|csv:101228027 1 379 + 379 Gaps:39 95.71 420 71.64 0.0 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|csv:101204146 1 379 + 379 Gaps:39 95.71 420 71.64 0.0 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|rcu:RCOM_0557340 1 380 + 380 Gaps:29 96.16 417 73.32 0.0 potassium channel regulatory factor putative
blastp_kegg lcl|pmum:103334132 1 380 + 380 Gaps:44 96.88 417 72.03 0.0 pre-mRNA-splicing factor 18
blastp_kegg lcl|cic:CICLE_v10020348mg 1 380 + 380 Gaps:36 96.15 416 72.75 0.0 hypothetical protein
blastp_kegg lcl|cit:102611778 1 380 + 380 Gaps:36 96.15 416 72.75 0.0 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|pper:PRUPE_ppa006327mg 1 380 + 380 Gaps:44 96.88 417 71.53 0.0 hypothetical protein
blastp_pdb 1dvk_B 288 343 + 56 Gaps:1 32.95 173 54.39 1e-11 mol:protein length:173 PRP18
blastp_pdb 1dvk_A 288 343 + 56 Gaps:1 32.95 173 54.39 1e-11 mol:protein length:173 PRP18
blastp_uniprot_sprot sp|Q8BM39|PRP18_MOUSE 1 361 + 361 Gaps:57 100.00 342 40.06 8e-61 Pre-mRNA-splicing factor 18 OS Mus musculus GN Prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q2HJ41|PRP18_BOVIN 1 361 + 361 Gaps:57 100.00 342 40.35 1e-60 Pre-mRNA-splicing factor 18 OS Bos taurus GN PRPF18 PE 2 SV 1
blastp_uniprot_sprot sp|Q99633|PRP18_HUMAN 1 361 + 361 Gaps:57 100.00 342 40.06 2e-60 Pre-mRNA-splicing factor 18 OS Homo sapiens GN PRPF18 PE 1 SV 1
blastp_uniprot_sprot sp|Q5RE03|PRP18_PONAB 1 361 + 361 Gaps:57 100.00 342 40.06 4e-60 Pre-mRNA-splicing factor 18 OS Pongo abelii GN PRPF18 PE 2 SV 1
blastp_uniprot_sprot sp|Q9JKB8|PRP18_RAT 1 361 + 361 Gaps:57 100.00 342 39.77 4e-60 Pre-mRNA-splicing factor 18 OS Rattus norvegicus GN Prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q6GMH0|PRP18_DANRE 1 361 + 361 Gaps:47 100.00 342 37.13 2e-56 Pre-mRNA-splicing factor 18 OS Danio rerio GN prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q5EAV6|PRP18_XENLA 1 361 + 361 Gaps:35 100.00 342 38.60 6e-54 Pre-mRNA-splicing factor 18 OS Xenopus laevis GN prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|O94406|PRP18_SCHPO 232 352 + 121 none 35.28 343 37.19 5e-23 Pre-mRNA-splicing factor 18 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN prp18 PE 3 SV 1
blastp_uniprot_sprot sp|P33411|PRP18_YEAST 288 343 + 56 Gaps:1 22.71 251 54.39 3e-11 Pre-mRNA-splicing factor 18 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN PRP18 PE 1 SV 3
rpsblast_cdd gnl|CDD|202426 208 350 + 143 none 99.31 144 55.24 2e-55 pfam02840 Prp18 Prp18 domain. The splicing factor Prp18 is required for the second step of pre-mRNA splicing. The structure of a large fragment of the Saccharomyces cerevisiae Prp18 is known. This fragment is fully active in yeast splicing in vitro and includes the sequences of Prp18 that have been evolutionarily conserved. The core structure consists of five alpha-helices that adopt a novel fold. The most highly conserved region of Prp18 a nearly invariant stretch of 19 aa forms part of a loop between two alpha-helices and may interact with the U5 small nuclear ribonucleoprotein particles.
rpsblast_cdd gnl|CDD|128776 87 131 + 45 Gaps:1 100.00 44 56.82 3e-08 smart00500 SFM Splicing Factor Motif present in Prp18 and Pr04.
rpsblast_kog gnl|CDD|38019 1 363 + 363 Gaps:28 100.00 341 44.28 3e-82 KOG2808 KOG2808 KOG2808 U5 snRNP-associated RNA splicing factor [RNA processing and modification].

8 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 367 367 PTHR13007:SF19 none none none
SUPERFAMILY 185 349 165 SSF47938 none none IPR004098
PANTHER 1 367 367 PTHR13007 none none none
SUPERFAMILY 81 122 42 SSF158230 none none none
SMART 87 138 52 SM00500 none Splicing Factor Motif, present in Prp18 and Pr04 IPR003648
Gene3D 185 354 170 G3DSA:1.20.940.10 none none IPR004098
Pfam 207 349 143 PF02840 none Prp18 domain IPR004098
Pfam 92 121 30 PF08799 none pre-mRNA processing factor 4 (PRP4) like IPR014906

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran_2000_2002_QTL6_Delta.F Qrob_Chr03 3 s_2HYXJ2_207 s_1AUAXK_317 29.12 6,3 45,37 lod 3.1666 0.026
Bourran2_2014_nLBD_3P Qrob_Chr03 3 s_1ET7H8_604 s_1BYNB5_834 23,73 0 46,72 lod 1,7573 3,8
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5
Bourran2_2014_rEpiBC*_3P Qrob_Chr03 3 s_1A3B3X_1163 s_1DKGMO_450 23,04 4,92 41,12 lod 2,5668 7

0 Targeting