Protein : Qrob_P0443980.2 Q. robur
Protein Identifier  ? Qrob_P0443980.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) 2.4.1.225 - N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase. Code Enzyme  EC:2.4.1.225, EC:2.4.1.224
Gene Prediction Quality  validated Protein length 

Sequence

Length: 354  
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0006024 glycosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
GO:0015012 heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100797004 1 353 + 353 Gaps:1 100.00 352 72.73 0.0 exostosin-2-like
blastp_kegg lcl|gmx:100781422 1 353 + 353 Gaps:1 100.00 352 71.88 3e-180 exostosin-2-like
blastp_kegg lcl|pmum:103333289 1 353 + 353 Gaps:12 100.00 359 68.25 1e-177 exostosin-like 2
blastp_kegg lcl|pvu:PHAVU_004G124500g 1 353 + 353 Gaps:4 100.00 353 69.69 6e-177 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa007532mg 1 353 + 353 Gaps:17 100.00 364 66.48 2e-168 hypothetical protein
blastp_kegg lcl|pda:103718232 19 353 + 335 Gaps:4 90.35 373 73.29 1e-162 exostosin-like 2
blastp_kegg lcl|mus:103998841 19 353 + 335 Gaps:5 87.43 382 67.96 2e-153 exostosin-2-like
blastp_kegg lcl|atr:s00029p00228900 29 353 + 325 none 98.78 329 61.23 7e-149 AMTR_s00029p00228900 hypothetical protein
blastp_kegg lcl|vvi:100260303 47 353 + 307 Gaps:1 91.12 338 59.42 2e-134 exostosin-2-like
blastp_kegg lcl|rcu:RCOM_0592150 41 353 + 313 Gaps:6 96.35 329 58.68 1e-133 Exostosin-2 putative (EC:2.4.1.223)
blastp_pdb 1on8_B 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on8_A 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on6_B 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on6_A 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omz_B 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omz_A 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omx_B 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omx_A 85 342 + 258 Gaps:39 88.40 293 33.98 1e-33 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_uniprot_sprot sp|Q9Y169|EXT2_DROME 77 344 + 268 Gaps:26 35.70 717 35.16 1e-33 Exostosin-2 OS Drosophila melanogaster GN Ext2 PE 1 SV 1
blastp_uniprot_sprot sp|P70428|EXT2_MOUSE 88 337 + 250 Gaps:29 33.29 718 35.98 5e-33 Exostosin-2 OS Mus musculus GN Ext2 PE 1 SV 2
blastp_uniprot_sprot sp|Q9ES89|EXTL2_MOUSE 85 342 + 258 Gaps:39 78.48 330 33.98 1e-32 Exostosin-like 2 OS Mus musculus GN Extl2 PE 1 SV 1
blastp_uniprot_sprot sp|Q93063|EXT2_HUMAN 88 337 + 250 Gaps:35 33.29 718 36.82 2e-32 Exostosin-2 OS Homo sapiens GN EXT2 PE 1 SV 1
blastp_uniprot_sprot sp|O77783|EXT2_BOVIN 88 337 + 250 Gaps:29 33.29 718 35.56 2e-32 Exostosin-2 OS Bos taurus GN EXT2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9UBQ6|EXTL2_HUMAN 93 342 + 250 Gaps:37 75.45 330 33.73 6e-32 Exostosin-like 2 OS Homo sapiens GN EXTL2 PE 1 SV 1
blastp_uniprot_sprot sp|Q5IGR8|EXT1A_DANRE 162 343 + 182 Gaps:14 24.93 730 39.56 3e-30 Exostosin-1a OS Danio rerio GN ext1a PE 2 SV 1
blastp_uniprot_sprot sp|O01705|EXT2_CAEEL 75 344 + 270 Gaps:36 31.94 814 33.85 2e-29 Exostosin-2 OS Caenorhabditis elegans GN rib-2 PE 2 SV 2
blastp_uniprot_sprot sp|Q5IGR7|EXT1B_DANRE 162 343 + 182 Gaps:14 24.56 741 39.01 4e-29 Exostosin-1b OS Danio rerio GN ext1b PE 2 SV 1
blastp_uniprot_sprot sp|Q9WVL6|EXTL3_MOUSE 89 344 + 256 Gaps:31 26.25 918 35.27 2e-28 Exostosin-like 3 OS Mus musculus GN Extl3 PE 2 SV 2
rpsblast_cdd gnl|CDD|192236 93 345 + 253 Gaps:23 98.36 244 42.08 3e-75 pfam09258 Glyco_transf_64 Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate.
rpsblast_kog gnl|CDD|36240 39 351 + 313 Gaps:27 43.42 691 37.67 3e-77 KOG1022 KOG1022 KOG1022 Acetylglucosaminyltransferase EXT2/exostosin 2 [Carbohydrate transport and metabolism Cell wall/membrane/envelope biogenesis Extracellular structures].

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 78 353 276 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 121 345 225 PTHR11062 none none none
Pfam 93 344 252 PF09258 none Glycosyl transferase family 64 domain IPR015338
Phobius 54 77 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1 53 53 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Gene3D 91 346 256 G3DSA:3.90.550.10 none none IPR029044
SUPERFAMILY 93 344 252 SSF53448 none none IPR029044

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4

0 Targeting