Protein : Qrob_P0410440.2 Q. robur
Protein Identifier  ? Qrob_P0410440.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K00020 - 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] Code Enzyme  EC:1.1.1.31
Gene Prediction Quality  validated Protein length 

Sequence

Length: 301  
Kegg Orthology  K00020
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0051287 NAD binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
GO:0008442 3-hydroxyisobutyrate dehydrogenase activity Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103325239 1 299 + 299 Gaps:1 85.14 350 84.23 0.0 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial
blastp_kegg lcl|pop:POPTR_0001s46990g 1 300 + 300 none 86.46 347 82.67 1e-180 POPTRDRAFT_550610 3-hydroxyisobutyrate dehydrogenase family protein
blastp_kegg lcl|fve:101306412 1 300 + 300 Gaps:2 86.71 346 82.00 9e-180 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial-like
blastp_kegg lcl|pxb:103952367 1 299 + 299 Gaps:1 84.90 351 80.87 2e-175 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial
blastp_kegg lcl|vvi:100242424 1 299 + 299 none 86.67 345 79.60 3e-175 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial-like
blastp_kegg lcl|mdm:103435630 1 299 + 299 Gaps:1 84.90 351 79.53 2e-173 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial
blastp_kegg lcl|rcu:RCOM_1337110 1 300 + 300 none 77.32 388 78.00 6e-169 3-hydroxyisobutyrate dehydrogenase putative (EC:1.1.1.31)
blastp_kegg lcl|tcc:TCM_026938 1 299 + 299 none 81.92 365 77.93 7e-168 6-phosphogluconate dehydrogenase family protein isoform 1
blastp_kegg lcl|cit:102613224 1 300 + 300 none 84.51 355 79.33 1e-167 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial-like
blastp_kegg lcl|cam:101500780 1 299 + 299 none 85.43 350 76.59 9e-167 probable 3-hydroxyisobutyrate dehydrogenase mitochondrial-like
blastp_pdb 2gf2_D 1 291 + 291 Gaps:12 94.26 296 50.54 2e-88 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_C 1 291 + 291 Gaps:12 94.26 296 50.54 2e-88 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_B 1 291 + 291 Gaps:12 94.26 296 50.54 2e-88 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_A 1 291 + 291 Gaps:12 94.26 296 50.54 2e-88 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2i9p_D 1 291 + 291 Gaps:12 87.46 319 50.54 4e-88 mol:protein length:319 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2i9p_C 1 291 + 291 Gaps:12 87.46 319 50.54 4e-88 mol:protein length:319 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2i9p_B 1 291 + 291 Gaps:12 87.46 319 50.54 4e-88 mol:protein length:319 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2i9p_A 1 291 + 291 Gaps:12 87.46 319 50.54 4e-88 mol:protein length:319 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 3q3c_A 1 293 + 293 Gaps:12 93.98 299 44.13 4e-58 mol:protein length:299 Probable 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 3obb_A 1 293 + 293 Gaps:12 93.67 300 44.13 5e-58 mol:protein length:300 Probable 3-hydroxyisobutyrate dehydrogenase
blastp_uniprot_sprot sp|Q9SUC0|3HIDH_ARATH 1 300 + 300 none 86.46 347 73.33 2e-164 Probable 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Arabidopsis thaliana GN At4g20930 PE 2 SV 3
blastp_uniprot_sprot sp|Q2HJD7|3HIDH_BOVIN 1 291 + 291 Gaps:12 83.04 336 51.25 2e-88 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Bos taurus GN HIBADH PE 2 SV 1
blastp_uniprot_sprot sp|Q5R5E7|3HIDH_PONAB 1 291 + 291 Gaps:12 83.04 336 50.54 2e-87 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Pongo abelii GN HIBADH PE 2 SV 1
blastp_uniprot_sprot sp|P31937|3HIDH_HUMAN 1 291 + 291 Gaps:12 83.04 336 50.54 2e-87 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Homo sapiens GN HIBADH PE 1 SV 2
blastp_uniprot_sprot sp|Q99L13|3HIDH_MOUSE 1 292 + 292 Gaps:12 83.58 335 50.36 1e-86 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Mus musculus GN Hibadh PE 1 SV 1
blastp_uniprot_sprot sp|P29266|3HIDH_RAT 1 292 + 292 Gaps:12 83.58 335 50.00 5e-86 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Rattus norvegicus GN Hibadh PE 1 SV 3
blastp_uniprot_sprot sp|Q54CX6|3HIDH_DICDI 1 290 + 290 Gaps:14 86.60 321 49.64 7e-80 Probable 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Dictyostelium discoideum GN hibA PE 3 SV 1
blastp_uniprot_sprot sp|Q9XTI0|3HIDH_CAEEL 1 291 + 291 Gaps:16 93.98 299 44.48 6e-66 Probable 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Caenorhabditis elegans GN B0250.5 PE 3 SV 1
blastp_uniprot_sprot sp|Q9V8M5|3HIDH_DROME 1 290 + 290 Gaps:20 85.19 324 45.65 2e-65 Probable 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Drosophila melanogaster GN CG15093 PE 2 SV 2
blastp_uniprot_sprot sp|P28811|MMSB_PSEAE 1 298 + 298 Gaps:15 96.31 298 41.46 1e-61 3-hydroxyisobutyrate dehydrogenase OS Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN mmsB PE 2 SV 1

10 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 292 292 PTHR22981 none none none
Gene3D 1 164 164 G3DSA:3.40.50.720 none none IPR016040
Gene3D 165 293 129 G3DSA:1.10.1040.10 none none IPR013328
TIGRFAM 1 293 293 TIGR01692 "KEGG:00280+1.1.1.31","UniPathway:UPA00362" HIBADH: 3-hydroxyisobutyrate dehydrogenase IPR011548
PIRSF 1 296 296 PIRSF000103 none none IPR015815
PANTHER 1 292 292 PTHR22981:SF7 none none none
SUPERFAMILY 165 293 129 SSF48179 none none IPR008927
SUPERFAMILY 1 164 164 SSF51735 none none none
Pfam 166 292 127 PF14833 none NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IPR029154
Pfam 1 164 164 PF03446 none NAD binding domain of 6-phosphogluconate dehydrogenase IPR006115

0 Localization

0 Qtllist

0 Targeting