Protein : Qrob_P0367190.2 Q. robur

Protein Identifier  ? Qrob_P0367190.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) 2.4.1.143 - Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase. Code Enzyme  EC:2.4.1.143
Gene Prediction Quality  validated Protein length 

Sequence

Length: 431  
Kegg Orthology  K00736

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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005795 Golgi stack The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
GO:0009312 oligosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.

16 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|mdm:103442995 1 423 + 423 Gaps:4 100.00 427 76.11 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
blastp_kegg lcl|mdm:103426276 1 423 + 423 Gaps:4 100.00 427 76.35 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like
blastp_kegg lcl|rcu:RCOM_0347110 1 429 + 429 Gaps:4 97.74 443 73.90 0.0 beta-1 2-n-acetylglucosaminyltransferase II putative (EC:2.4.1.143)
blastp_kegg lcl|vvi:100240895 1 428 + 428 Gaps:4 98.86 437 75.93 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like
blastp_kegg lcl|pmum:103329256 1 423 + 423 Gaps:14 100.00 411 76.89 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
blastp_kegg lcl|pvu:PHAVU_007G239000g 1 428 + 428 Gaps:6 98.17 438 72.79 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0014s16520g 2 430 + 429 Gaps:4 98.63 439 75.75 0.0 POPTRDRAFT_896156 hypothetical protein
blastp_kegg lcl|cam:101500842 1 430 + 430 Gaps:4 98.64 440 73.27 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like
blastp_kegg lcl|cit:102618199 2 429 + 428 Gaps:5 98.17 437 75.52 0.0 alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like
blastp_kegg lcl|cic:CICLE_v10015287mg 2 429 + 428 Gaps:5 98.17 437 75.52 0.0 hypothetical protein
blastp_uniprot_sprot sp|O19071|MGAT2_PIG 86 420 + 335 Gaps:28 76.46 446 33.14 1e-56 Alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS Sus scrofa GN MGAT2 PE 3 SV 1
blastp_uniprot_sprot sp|Q10469|MGAT2_HUMAN 86 420 + 335 Gaps:37 76.51 447 33.63 5e-55 Alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS Homo sapiens GN MGAT2 PE 1 SV 1
blastp_uniprot_sprot sp|Q921V5|MGAT2_MOUSE 14 420 + 407 Gaps:64 99.32 442 30.30 3e-53 Alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS Mus musculus GN Mgat2 PE 2 SV 1
blastp_uniprot_sprot sp|Q09326|MGAT2_RAT 86 420 + 335 Gaps:37 77.38 442 32.46 1e-52 Alpha-1 6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS Rattus norvegicus GN Mgat2 PE 1 SV 1
rpsblast_cdd gnl|CDD|191181 74 414 + 341 Gaps:31 100.00 356 55.90 1e-150 pfam05060 MGAT2 N-acetylglucosaminyltransferase II (MGAT2). UDP-N-acetyl-D-glucosamine:alpha-6-D-mannoside beta-1 2-N- acetylglucosaminyltransferase II (EC 2.4.1.143) (GnT II/MGAT2) is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides. Mutations in the MGAT2 gene lead to congenital disorder of glycosylation (CDG IIa). CDG IIa patients have an increased bleeding tendency unrelated to coagulation factors.
rpsblast_kog gnl|CDD|38002 86 430 + 345 Gaps:11 76.92 455 61.43 1e-133 KOG2791 KOG2791 KOG2791 N-acetylglucosaminyltransferase [Carbohydrate transport and metabolism].

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 41 430 390 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 16 16 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
PANTHER 67 425 359 PTHR12871 "KEGG:00510+2.4.1.143","KEGG:00513+2.4.1.143","MetaCyc:PWY-7426","UniPathway:UPA00378";signature_desc=BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II none IPR007754
Pfam 76 414 339 PF05060 "KEGG:00510+2.4.1.143","KEGG:00513+2.4.1.143","MetaCyc:PWY-7426","UniPathway:UPA00378" N-acetylglucosaminyltransferase II (MGAT2) IPR007754
SUPERFAMILY 97 168 72 SSF53448 none none IPR029044
SUPERFAMILY 207 417 211 SSF53448 none none IPR029044
Phobius 17 35 19 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
PANTHER 67 425 359 PTHR12871:SF0 none none none
Phobius 1 40 40 SIGNAL_PEPTIDE none Signal peptide region none
Phobius 36 40 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Gene3D 99 317 219 G3DSA:3.90.550.10 none none IPR029044

1 Localization

Analysis Start End Length
TMHMM 13 35 22

0 Qtllist

0 Targeting