Protein : Qrob_P0346350.2 Q. robur

Protein Identifier  ? Qrob_P0346350.2 Organism . Name  Quercus robur
Score  80.0 Score Type  egn
Protein Description  (M=3) K01191 - alpha-mannosidase [EC:3.2.1.24] Code Enzyme  EC:3.2.1.24
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1013  
Kegg Orthology  K01191

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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0008270 zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.
GO:0030246 carbohydrate binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:0006013 mannose metabolic process The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
GO:0015923 mannosidase activity Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.
GO:0004559 alpha-mannosidase activity Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa021513mg 9 1012 + 1004 Gaps:6 99.11 1015 80.32 0.0 hypothetical protein
blastp_kegg lcl|pmum:103340418 9 1012 + 1004 Gaps:4 99.11 1013 80.08 0.0 lysosomal alpha-mannosidase
blastp_kegg lcl|tcc:TCM_000183 1 1012 + 1012 Gaps:4 100.00 1012 78.66 0.0 Fatty acid hydroxylase superfamily isoform 2
blastp_kegg lcl|vvi:100259071 5 1012 + 1008 Gaps:4 100.00 1006 78.93 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|cit:102627207 11 1012 + 1002 Gaps:10 99.20 1004 79.22 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|pop:POPTR_0007s09730g 10 1012 + 1003 Gaps:8 99.01 1011 79.62 0.0 hypothetical protein
blastp_kegg lcl|pxb:103967794 27 1012 + 986 Gaps:6 97.44 1016 79.49 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|mdm:103418267 27 1012 + 986 Gaps:6 97.44 1016 79.09 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|fve:101297194 27 1012 + 986 Gaps:7 92.82 1059 78.84 0.0 lysosomal alpha-mannosidase-like
blastp_kegg lcl|gmx:100806748 5 1012 + 1008 Gaps:8 100.00 1012 77.47 0.0 lysosomal alpha-mannosidase-like
blastp_pdb 1o7d_A 34 327 + 294 Gaps:4 99.33 298 47.97 8e-88 mol:protein length:298 LYSOSOMAL ALPHA-MANNOSIDASE
blastp_pdb 1hxk_A 29 828 + 800 Gaps:92 80.59 1015 29.58 3e-87 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 1hww_A 29 828 + 800 Gaps:92 80.59 1015 29.58 3e-87 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 1hty_A 29 828 + 800 Gaps:92 80.59 1015 29.58 3e-87 mol:protein length:1015 ALPHA-MANNOSIDASE II
blastp_pdb 3eju_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejt_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejs_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejr_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejq_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_pdb 3ejp_A 29 828 + 800 Gaps:92 78.28 1045 29.58 4e-87 mol:protein length:1045 Alpha-mannosidase 2
blastp_uniprot_sprot sp|O09159|MA2B1_MOUSE 16 1009 + 994 Gaps:63 95.66 1013 41.69 0.0 Lysosomal alpha-mannosidase OS Mus musculus GN Man2b1 PE 2 SV 4
blastp_uniprot_sprot sp|Q8VHC8|MA2B1_CAVPO 34 1009 + 976 Gaps:87 94.24 1007 42.68 0.0 Lysosomal alpha-mannosidase OS Cavia porcellus GN MAN2B1 PE 1 SV 1
blastp_uniprot_sprot sp|O46432|MA2B1_FELCA 34 1009 + 976 Gaps:66 93.94 1007 41.97 0.0 Lysosomal alpha-mannosidase OS Felis catus GN MAN2B1 PE 2 SV 1
blastp_uniprot_sprot sp|O00754|MA2B1_HUMAN 34 1009 + 976 Gaps:62 93.97 1011 41.89 0.0 Lysosomal alpha-mannosidase OS Homo sapiens GN MAN2B1 PE 1 SV 3
blastp_uniprot_sprot sp|Q60HE9|MA2B1_MACFA 34 1009 + 976 Gaps:62 93.87 1012 41.68 0.0 Lysosomal alpha-mannosidase OS Macaca fascicularis GN MAN2B1 PE 2 SV 1
blastp_uniprot_sprot sp|Q29451|MA2B1_BOVIN 34 1009 + 976 Gaps:88 93.89 999 42.64 0.0 Lysosomal alpha-mannosidase OS Bos taurus GN MAN2B1 PE 1 SV 4
blastp_uniprot_sprot sp|P34098|MANA_DICDI 45 1010 + 966 Gaps:86 95.64 1010 39.75 0.0 Lysosomal alpha-mannosidase OS Dictyostelium discoideum GN manA PE 1 SV 2
blastp_uniprot_sprot sp|Q16706|MA2A1_HUMAN 45 831 + 787 Gaps:101 70.63 1144 28.47 4e-87 Alpha-mannosidase 2 OS Homo sapiens GN MAN2A1 PE 1 SV 2
blastp_uniprot_sprot sp|P49641|MA2A2_HUMAN 45 1012 + 968 Gaps:126 85.57 1150 29.17 4e-87 Alpha-mannosidase 2x OS Homo sapiens GN MAN2A2 PE 2 SV 3
blastp_uniprot_sprot sp|Q24451|MAN2_DROME 29 828 + 800 Gaps:92 73.83 1108 29.58 1e-86 Alpha-mannosidase 2 OS Drosophila melanogaster GN alpha-Man-II PE 1 SV 2

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 25 25 SIGNAL_PEPTIDE none Signal peptide region none
SUPERFAMILY 361 455 95 SSF88688 none none IPR028995
Pfam 496 1009 514 PF07748 none Glycosyl hydrolases family 38 C-terminal domain IPR011682
PANTHER 26 1012 987 PTHR11607:SF18 none none none
Phobius 1 7 7 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Phobius 22 25 4 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Pfam 46 357 312 PF01074 none Glycosyl hydrolases family 38 N-terminal domain IPR000602
Gene3D 29 359 331 G3DSA:3.20.110.10 none none IPR027291
Gene3D 895 1012 118 G3DSA:2.60.40.1360 none none none
Gene3D 614 871 258 G3DSA:2.70.98.30 none none none
Phobius 26 1012 987 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 464 1012 549 SSF74650 none none IPR011013
SMART 362 436 75 SM00872 none Alpha mannosidase, middle domain IPR015341
Phobius 8 21 14 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Pfam 363 436 74 PF09261 none Alpha mannosidase, middle domain IPR015341
Gene3D 471 613 143 G3DSA:2.60.40.1180 none none IPR013780
PANTHER 26 1012 987 PTHR11607 none none none
SUPERFAMILY 34 358 325 SSF88713 none none IPR011330
Gene3D 361 462 102 G3DSA:1.20.1270.50 none none IPR015341

2 Localization

Analysis Start End Length
SignalP_EUK 1 29 28
TMHMM 5 27 22

0 Qtllist

0 Targeting