8 GO Terms
Identifier | Name | Description |
---|---|---|
GO:0008270 | zinc ion binding | Interacting selectively and non-covalently with zinc (Zn) ions. |
GO:0003824 | catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. |
GO:0005975 | carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | Catalysis of the hydrolysis of any O-glycosyl bond. |
GO:0030246 | carbohydrate binding | Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. |
GO:0006013 | mannose metabolic process | The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. |
GO:0015923 | mannosidase activity | Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative. |
GO:0004559 | alpha-mannosidase activity | Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. |
42 Blast
Analysis | Hit | Start | End | Strand | Length | Note | Hit Coverage | Hit Length | Hit Pident | E Val | Hit Description |
---|---|---|---|---|---|---|---|---|---|---|---|
blastp_kegg | lcl|pper:PRUPE_ppa021513mg | 9 | 1012 | + | 1004 | Gaps:6 | 99.11 | 1015 | 80.32 | 0.0 | hypothetical protein |
blastp_kegg | lcl|pmum:103340418 | 9 | 1012 | + | 1004 | Gaps:4 | 99.11 | 1013 | 80.08 | 0.0 | lysosomal alpha-mannosidase |
blastp_kegg | lcl|tcc:TCM_000183 | 1 | 1012 | + | 1012 | Gaps:4 | 100.00 | 1012 | 78.66 | 0.0 | Fatty acid hydroxylase superfamily isoform 2 |
blastp_kegg | lcl|vvi:100259071 | 5 | 1012 | + | 1008 | Gaps:4 | 100.00 | 1006 | 78.93 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_kegg | lcl|cit:102627207 | 11 | 1012 | + | 1002 | Gaps:10 | 99.20 | 1004 | 79.22 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_kegg | lcl|pop:POPTR_0007s09730g | 10 | 1012 | + | 1003 | Gaps:8 | 99.01 | 1011 | 79.62 | 0.0 | hypothetical protein |
blastp_kegg | lcl|pxb:103967794 | 27 | 1012 | + | 986 | Gaps:6 | 97.44 | 1016 | 79.49 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_kegg | lcl|mdm:103418267 | 27 | 1012 | + | 986 | Gaps:6 | 97.44 | 1016 | 79.09 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_kegg | lcl|fve:101297194 | 27 | 1012 | + | 986 | Gaps:7 | 92.82 | 1059 | 78.84 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_kegg | lcl|gmx:100806748 | 5 | 1012 | + | 1008 | Gaps:8 | 100.00 | 1012 | 77.47 | 0.0 | lysosomal alpha-mannosidase-like |
blastp_pdb | 1o7d_A | 34 | 327 | + | 294 | Gaps:4 | 99.33 | 298 | 47.97 | 8e-88 | mol:protein length:298 LYSOSOMAL ALPHA-MANNOSIDASE |
blastp_pdb | 1hxk_A | 29 | 828 | + | 800 | Gaps:92 | 80.59 | 1015 | 29.58 | 3e-87 | mol:protein length:1015 ALPHA-MANNOSIDASE II |
blastp_pdb | 1hww_A | 29 | 828 | + | 800 | Gaps:92 | 80.59 | 1015 | 29.58 | 3e-87 | mol:protein length:1015 ALPHA-MANNOSIDASE II |
blastp_pdb | 1hty_A | 29 | 828 | + | 800 | Gaps:92 | 80.59 | 1015 | 29.58 | 3e-87 | mol:protein length:1015 ALPHA-MANNOSIDASE II |
blastp_pdb | 3eju_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_pdb | 3ejt_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_pdb | 3ejs_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_pdb | 3ejr_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_pdb | 3ejq_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_pdb | 3ejp_A | 29 | 828 | + | 800 | Gaps:92 | 78.28 | 1045 | 29.58 | 4e-87 | mol:protein length:1045 Alpha-mannosidase 2 |
blastp_uniprot_sprot | sp|O09159|MA2B1_MOUSE | 16 | 1009 | + | 994 | Gaps:63 | 95.66 | 1013 | 41.69 | 0.0 | Lysosomal alpha-mannosidase OS Mus musculus GN Man2b1 PE 2 SV 4 |
blastp_uniprot_sprot | sp|Q8VHC8|MA2B1_CAVPO | 34 | 1009 | + | 976 | Gaps:87 | 94.24 | 1007 | 42.68 | 0.0 | Lysosomal alpha-mannosidase OS Cavia porcellus GN MAN2B1 PE 1 SV 1 |
blastp_uniprot_sprot | sp|O46432|MA2B1_FELCA | 34 | 1009 | + | 976 | Gaps:66 | 93.94 | 1007 | 41.97 | 0.0 | Lysosomal alpha-mannosidase OS Felis catus GN MAN2B1 PE 2 SV 1 |
blastp_uniprot_sprot | sp|O00754|MA2B1_HUMAN | 34 | 1009 | + | 976 | Gaps:62 | 93.97 | 1011 | 41.89 | 0.0 | Lysosomal alpha-mannosidase OS Homo sapiens GN MAN2B1 PE 1 SV 3 |
blastp_uniprot_sprot | sp|Q60HE9|MA2B1_MACFA | 34 | 1009 | + | 976 | Gaps:62 | 93.87 | 1012 | 41.68 | 0.0 | Lysosomal alpha-mannosidase OS Macaca fascicularis GN MAN2B1 PE 2 SV 1 |
blastp_uniprot_sprot | sp|Q29451|MA2B1_BOVIN | 34 | 1009 | + | 976 | Gaps:88 | 93.89 | 999 | 42.64 | 0.0 | Lysosomal alpha-mannosidase OS Bos taurus GN MAN2B1 PE 1 SV 4 |
blastp_uniprot_sprot | sp|P34098|MANA_DICDI | 45 | 1010 | + | 966 | Gaps:86 | 95.64 | 1010 | 39.75 | 0.0 | Lysosomal alpha-mannosidase OS Dictyostelium discoideum GN manA PE 1 SV 2 |
blastp_uniprot_sprot | sp|Q16706|MA2A1_HUMAN | 45 | 831 | + | 787 | Gaps:101 | 70.63 | 1144 | 28.47 | 4e-87 | Alpha-mannosidase 2 OS Homo sapiens GN MAN2A1 PE 1 SV 2 |
blastp_uniprot_sprot | sp|P49641|MA2A2_HUMAN | 45 | 1012 | + | 968 | Gaps:126 | 85.57 | 1150 | 29.17 | 4e-87 | Alpha-mannosidase 2x OS Homo sapiens GN MAN2A2 PE 2 SV 3 |
blastp_uniprot_sprot | sp|Q24451|MAN2_DROME | 29 | 828 | + | 800 | Gaps:92 | 73.83 | 1108 | 29.58 | 1e-86 | Alpha-mannosidase 2 OS Drosophila melanogaster GN alpha-Man-II PE 1 SV 2 |
19 Domain Motifs
Analysis | Begin | End | Length | Domain Identifier | Cross Ref | Description | Inter Pro |
---|---|---|---|---|---|---|---|
Phobius | 1 | 25 | 25 | SIGNAL_PEPTIDE | none | Signal peptide region | none |
SUPERFAMILY | 361 | 455 | 95 | SSF88688 | none | none | IPR028995 |
Pfam | 496 | 1009 | 514 | PF07748 | none | Glycosyl hydrolases family 38 C-terminal domain | IPR011682 |
PANTHER | 26 | 1012 | 987 | PTHR11607:SF18 | none | none | none |
Phobius | 1 | 7 | 7 | SIGNAL_PEPTIDE_N_REGION | none | N-terminal region of a signal peptide. | none |
Phobius | 22 | 25 | 4 | SIGNAL_PEPTIDE_C_REGION | none | C-terminal region of a signal peptide. | none |
Pfam | 46 | 357 | 312 | PF01074 | none | Glycosyl hydrolases family 38 N-terminal domain | IPR000602 |
Gene3D | 29 | 359 | 331 | G3DSA:3.20.110.10 | none | none | IPR027291 |
Gene3D | 895 | 1012 | 118 | G3DSA:2.60.40.1360 | none | none | none |
Gene3D | 614 | 871 | 258 | G3DSA:2.70.98.30 | none | none | none |
Phobius | 26 | 1012 | 987 | NON_CYTOPLASMIC_DOMAIN | none | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | none |
SUPERFAMILY | 464 | 1012 | 549 | SSF74650 | none | none | IPR011013 |
SMART | 362 | 436 | 75 | SM00872 | none | Alpha mannosidase, middle domain | IPR015341 |
Phobius | 8 | 21 | 14 | SIGNAL_PEPTIDE_H_REGION | none | Hydrophobic region of a signal peptide. | none |
Pfam | 363 | 436 | 74 | PF09261 | none | Alpha mannosidase, middle domain | IPR015341 |
Gene3D | 471 | 613 | 143 | G3DSA:2.60.40.1180 | none | none | IPR013780 |
PANTHER | 26 | 1012 | 987 | PTHR11607 | none | none | none |
SUPERFAMILY | 34 | 358 | 325 | SSF88713 | none | none | IPR011330 |
Gene3D | 361 | 462 | 102 | G3DSA:1.20.1270.50 | none | none | IPR015341 |