Protein : Qrob_P0343080.2 Q. robur
Protein Identifier  ? Qrob_P0343080.2 Organism . Name  Quercus robur
Score  8.2 Score Type  egn
Protein Description  (M=2) 1.1.1.291 - 2-hydroxymethylglutarate dehydrogenase. Code Enzyme  EC:1.1.1.291
Gene Prediction Quality  validated Protein length 

Sequence

Length: 658  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0016491 oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0051287 NAD binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103338684 17 637 + 621 Gaps:69 61.23 1367 67.86 0.0 uncharacterized LOC103338684
blastp_kegg lcl|pper:PRUPE_ppa000357mg 17 637 + 621 Gaps:63 58.03 1251 72.87 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0015s04720g 15 637 + 623 Gaps:46 56.98 1218 76.08 0.0 POPTRDRAFT_733116 hypothetical protein
blastp_kegg lcl|tcc:TCM_012876 4 637 + 634 Gaps:48 61.54 1373 66.63 0.0 Ketose-bisphosphate aldolase class-II family protein isoform 1
blastp_kegg lcl|mdm:103455635 17 637 + 621 Gaps:53 61.29 1369 66.39 0.0 uncharacterized LOC103455635
blastp_kegg lcl|cit:102621925 15 641 + 627 Gaps:52 64.45 1322 65.61 0.0 uncharacterized LOC102621925
blastp_kegg lcl|pxb:103950568 17 637 + 621 Gaps:53 61.29 1369 65.79 0.0 uncharacterized LOC103950568
blastp_kegg lcl|fve:101292421 17 637 + 621 Gaps:62 61.42 1371 64.96 0.0 uncharacterized protein LOC101292421
blastp_kegg lcl|crb:CARUB_v10011390mg 15 637 + 623 Gaps:46 61.62 1373 64.89 0.0 hypothetical protein
blastp_kegg lcl|aly:ARALYDRAFT_472044 15 637 + 623 Gaps:49 61.70 1376 64.43 0.0 ketose-bisphosphate aldolase class-II family protein
blastp_pdb 3g0o_A 105 391 + 287 Gaps:7 94.39 303 43.01 3e-62 mol:protein length:303 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 3cky_D 105 400 + 296 Gaps:4 97.67 301 36.39 4e-45 mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase
blastp_pdb 3cky_C 105 400 + 296 Gaps:4 97.67 301 36.39 4e-45 mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase
blastp_pdb 3cky_B 105 400 + 296 Gaps:4 97.67 301 36.39 4e-45 mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase
blastp_pdb 3cky_A 105 400 + 296 Gaps:4 97.67 301 36.39 4e-45 mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase
blastp_pdb 2gf2_D 106 388 + 283 Gaps:10 96.96 296 29.97 3e-35 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_C 106 388 + 283 Gaps:10 96.96 296 29.97 3e-35 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_B 106 388 + 283 Gaps:10 96.96 296 29.97 3e-35 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2gf2_A 106 388 + 283 Gaps:10 96.96 296 29.97 3e-35 mol:protein length:296 3-hydroxyisobutyrate dehydrogenase
blastp_pdb 2i9p_D 106 388 + 283 Gaps:10 89.97 319 29.97 7e-35 mol:protein length:319 3-hydroxyisobutyrate dehydrogenase
blastp_uniprot_sprot sp|Q46888|YGBJ_ECOLI 105 394 + 290 Gaps:3 95.70 302 42.91 9e-65 Uncharacterized oxidoreductase YgbJ OS Escherichia coli (strain K12) GN ygbJ PE 3 SV 1
blastp_uniprot_sprot sp|P44979|Y1010_HAEIN 106 394 + 289 Gaps:3 95.68 301 40.62 6e-59 Uncharacterized oxidoreductase HI_1010 OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN HI_1010 PE 3 SV 1
blastp_uniprot_sprot sp|Q0QLF5|HMGD_EUBBA 105 400 + 296 Gaps:4 97.67 301 36.39 1e-44 2-(hydroxymethyl)glutarate dehydrogenase OS Eubacterium barkeri GN Hgd PE 1 SV 1
blastp_uniprot_sprot sp|P31937|3HIDH_HUMAN 106 388 + 283 Gaps:10 85.42 336 29.97 5e-34 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Homo sapiens GN HIBADH PE 1 SV 2
blastp_uniprot_sprot sp|Q5R5E7|3HIDH_PONAB 106 388 + 283 Gaps:10 85.42 336 29.97 6e-34 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Pongo abelii GN HIBADH PE 2 SV 1
blastp_uniprot_sprot sp|P29266|3HIDH_RAT 106 388 + 283 Gaps:12 85.67 335 31.01 8e-34 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Rattus norvegicus GN Hibadh PE 1 SV 3
blastp_uniprot_sprot sp|Q99L13|3HIDH_MOUSE 106 388 + 283 Gaps:10 85.67 335 29.97 2e-33 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Mus musculus GN Hibadh PE 1 SV 1
blastp_uniprot_sprot sp|Q2HJD7|3HIDH_BOVIN 106 388 + 283 Gaps:10 85.42 336 30.31 4e-33 3-hydroxyisobutyrate dehydrogenase mitochondrial OS Bos taurus GN HIBADH PE 2 SV 1
blastp_uniprot_sprot sp|O34948|YKWC_BACSU 106 391 + 286 Gaps:6 97.22 288 31.43 2e-31 Uncharacterized oxidoreductase YkwC OS Bacillus subtilis (strain 168) GN ykwC PE 3 SV 1
blastp_uniprot_sprot sp|O33730|Y1503_SHEFN 105 391 + 287 Gaps:6 97.94 291 31.58 1e-29 Uncharacterized oxidoreductase Sfri_1503 OS Shewanella frigidimarina (strain NCIMB 400) GN Sfri_1503 PE 3 SV 2

10 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 72 433 362 PTHR22981:SF27 none none none
PANTHER 72 433 362 PTHR22981 none none none
SUPERFAMILY 437 635 199 SSF142764 none none none
SUPERFAMILY 104 261 158 SSF51735 none none none
Gene3D 105 264 160 G3DSA:3.40.50.720 none none IPR016040
SUPERFAMILY 270 395 126 SSF48179 none none IPR008927
ProSitePatterns 108 121 14 PS00895 none 3-hydroxyisobutyrate dehydrogenase signature. IPR002204
Gene3D 270 396 127 G3DSA:1.10.1040.10 none none IPR013328
Pfam 270 390 121 PF14833 none NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase IPR029154
Pfam 104 263 160 PF03446 none NAD binding domain of 6-phosphogluconate dehydrogenase IPR006115

0 Localization

0 Qtllist

0 Targeting