Protein : Qrob_P0336150.2 Q. robur

Protein Identifier  ? Qrob_P0336150.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=1) 2.7.1.105 - 6-phosphofructo-2-kinase. Code Enzyme  EC:2.7.1.105, EC:3.1.3.46
Gene Prediction Quality  validated Protein length 

Sequence

Length: 596  
Kegg Orthology  K01103

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0 Synonyms

8 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0030246 carbohydrate binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:2001070 starch binding Interacting selectively and non-covalently with starch.
GO:0006003 fructose 2,6-bisphosphate metabolic process The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
GO:0003873 6-phosphofructo-2-kinase activity Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).
GO:0006000 fructose metabolic process The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.

34 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100244966 1 574 + 574 Gaps:18 78.31 756 83.11 0.0 6-phosphofructo-2-kinase/fructose-2 6-biphosphatase 3-like
blastp_kegg lcl|pop:POPTR_0001s28590g 1 574 + 574 Gaps:28 78.07 748 82.53 0.0 POPTRDRAFT_815458 FRUCTOSE-2 family protein
blastp_kegg lcl|cic:CICLE_v10027872mg 1 574 + 574 Gaps:23 84.26 699 81.66 0.0 hypothetical protein
blastp_kegg lcl|cmo:103502919 1 575 + 575 Gaps:24 78.32 752 81.83 0.0 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase
blastp_kegg lcl|tcc:TCM_042176 1 574 + 574 Gaps:37 77.75 737 82.55 0.0 Fructose-2 6-bisphosphatase isoform 1
blastp_kegg lcl|rcu:RCOM_1668120 1 569 + 569 Gaps:32 81.04 712 82.67 0.0 fructose-6-phosphate 2-kinase/fructose-2 6-bisphosphatase putative (EC:3.1.3.46)
blastp_kegg lcl|pper:PRUPE_ppa001820mg 1 574 + 574 Gaps:22 78.42 760 80.20 0.0 hypothetical protein
blastp_kegg lcl|pmum:103321282 1 574 + 574 Gaps:22 78.42 760 80.20 0.0 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase
blastp_kegg lcl|pop:POPTR_0009s07790g 1 574 + 574 Gaps:27 78.05 747 80.62 0.0 POPTRDRAFT_557657 POPTRDRAFT_821351 hypothetical protein
blastp_kegg lcl|csv:101214487 1 573 + 573 Gaps:25 78.03 751 81.74 0.0 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase-like
blastp_pdb 1k6m_B 357 574 + 218 Gaps:29 54.86 432 42.62 8e-51 mol:protein length:432 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 1k6m_A 357 574 + 218 Gaps:29 54.86 432 42.62 8e-51 mol:protein length:432 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 3qpw_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-bisphos
blastp_pdb 3qpv_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-bisphos
blastp_pdb 3qpu_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 2i1v_B 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 2dwp_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 2dwo_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 2axn_A 348 574 + 227 Gaps:32 47.88 520 41.77 1e-49 mol:protein length:520 6-phosphofructo-2-kinase/fructose-2 6-biphosp
blastp_pdb 3bif_A 357 574 + 218 Gaps:32 50.85 468 42.86 2e-47 mol:protein length:468 PROTEIN (6-PHOSPHOFRUCTO-2-KINASE/ FRUCTOSE-2
blastp_uniprot_sprot sp|Q9MB58|F26_ARATH 1 574 + 574 Gaps:30 77.96 744 73.62 0.0 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase OS Arabidopsis thaliana GN FKFBP PE 1 SV 1
blastp_uniprot_sprot sp|P16118|F261_HUMAN 357 574 + 218 Gaps:29 50.32 471 43.04 5e-51 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 1 OS Homo sapiens GN PFKFB1 PE 1 SV 3
blastp_uniprot_sprot sp|P49872|F261_BOVIN 357 574 + 218 Gaps:29 50.32 471 42.62 3e-50 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 1 OS Bos taurus GN PFKFB1 PE 2 SV 1
blastp_uniprot_sprot sp|Q21122|F26_CAEEL 357 578 + 222 Gaps:34 54.27 457 41.53 1e-49 Probable 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase OS Caenorhabditis elegans GN K02B2.1 PE 3 SV 2
blastp_uniprot_sprot sp|P07953|F261_RAT 357 574 + 218 Gaps:29 50.32 471 42.19 1e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 1 OS Rattus norvegicus GN Pfkfb1 PE 1 SV 3
blastp_uniprot_sprot sp|P70266|F261_MOUSE 357 574 + 218 Gaps:29 50.32 471 42.19 3e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 1 OS Mus musculus GN Pfkfb1 PE 2 SV 2
blastp_uniprot_sprot sp|Q16875|F263_HUMAN 348 574 + 227 Gaps:32 47.88 520 41.77 5e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 3 OS Homo sapiens GN PFKFB3 PE 1 SV 1
blastp_uniprot_sprot sp|Q28901|F263_BOVIN 348 574 + 227 Gaps:31 54.00 463 40.80 5e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 3 (Fragment) OS Bos taurus GN PFKFB3 PE 2 SV 2
blastp_uniprot_sprot sp|Q5R9C1|F263_PONAB 348 574 + 227 Gaps:32 48.44 514 41.77 5e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 3 OS Pongo abelii GN PFKFB3 PE 2 SV 2
blastp_uniprot_sprot sp|O35552|F263_RAT 348 574 + 227 Gaps:32 44.86 555 41.77 8e-49 6-phosphofructo-2-kinase/fructose-2 6-bisphosphatase 3 OS Rattus norvegicus GN Pfkfb3 PE 2 SV 1

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 355 537 183 G3DSA:3.40.50.300 none none IPR027417
PANTHER 12 574 563 PTHR10606 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474";signature_desc=6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE none IPR003094
PIRSF 19 575 557 PIRSF000709 none none none
Gene3D 29 113 85 G3DSA:2.60.40.10 none none IPR013783
Gene3D 544 576 33 G3DSA:3.40.50.1240 none none IPR029033
Coils 484 505 22 Coil none none none
SUPERFAMILY 353 545 193 SSF52540 none none IPR027417
Pfam 345 544 200 PF01591 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474" 6-phosphofructo-2-kinase IPR013079
PRINTS 446 460 15 PR00991 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474" 6-phosphofructo-2-kinase family signature IPR003094
PRINTS 525 546 22 PR00991 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474" 6-phosphofructo-2-kinase family signature IPR003094
PRINTS 547 569 23 PR00991 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474" 6-phosphofructo-2-kinase family signature IPR003094
PRINTS 421 435 15 PR00991 "KEGG:00051+2.7.1.105+3.1.3.46","Reactome:REACT_474" 6-phosphofructo-2-kinase family signature IPR003094
SUPERFAMILY 545 576 32 SSF53254 none none IPR029033
Pfam 49 113 65 PF00686 none Starch binding domain IPR002044
SMART 29 121 93 SM01065 none Starch binding domain IPR002044
ProSiteProfiles 24 129 106 PS51166 none CBM20 (carbohydrate binding type-20) domain profile. IPR002044
PANTHER 12 574 563 PTHR10606:SF32 none none none
ProSitePatterns 549 558 10 PS00175 "UniPathway:UPA00109" Phosphoglycerate mutase family phosphohistidine signature. IPR001345
SUPERFAMILY 27 116 90 SSF49452 none none IPR013784

0 Localization

0 Qtllist

0 Targeting