Protein : Qrob_P0324710.2 Q. robur
Protein Identifier  ? Qrob_P0324710.2 Organism . Name  Quercus robur
Score  96.0 Score Type  egn
Protein Description  (M=3) 1.1.1.42 - Isocitrate dehydrogenase (NADP(+)). Code Enzyme  EC:1.1.1.42
Gene Prediction Quality  validated Protein length 

Sequence

Length: 431  
Kegg Orthology  K00031
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0051287 NAD binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
GO:0004450 isocitrate dehydrogenase (NADP+) activity Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.
GO:0006102 isocitrate metabolic process The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.
GO:0000287 magnesium ion binding Interacting selectively and non-covalently with magnesium (Mg) ions.

39 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pop:POPTR_0004s07320g 1 429 + 429 Gaps:18 99.28 414 94.16 0.0 POPTRDRAFT_648243 isocitrate dehydrogenase family protein
blastp_kegg lcl|rcu:RCOM_0113200 1 429 + 429 Gaps:18 99.52 413 93.92 0.0 NADP-specific isocitrate dehydrogenase putative (EC:1.1.1.42)
blastp_kegg lcl|cit:102609279 1 429 + 429 Gaps:18 99.28 414 93.67 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|cic:CICLE_v10001314mg 1 429 + 429 Gaps:18 99.28 414 92.94 0.0 hypothetical protein
blastp_kegg lcl|vvi:100261578 1 429 + 429 Gaps:18 99.76 412 92.70 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|pop:POPTR_0017s01410g 1 429 + 429 Gaps:22 99.27 410 94.35 0.0 isocitrate dehydrogenase family protein
blastp_kegg lcl|tcc:TCM_016778 1 429 + 429 Gaps:18 89.15 461 92.21 0.0 Cytosolic NADP+-dependent isocitrate dehydrogenase isoform 1
blastp_kegg lcl|mus:103980394 1 429 + 429 Gaps:20 99.76 410 92.91 0.0 cytosolic isocitrate dehydrogenase [NADP]
blastp_kegg lcl|cam:101490353 1 429 + 429 Gaps:18 99.76 412 90.27 0.0 isocitrate dehydrogenase [NADP] chloroplastic-like
blastp_kegg lcl|pxb:103956814 1 429 + 429 Gaps:18 99.76 412 90.27 0.0 isocitrate dehydrogenase [NADP]
blastp_pdb 1lwd_B 2 428 + 427 Gaps:21 99.27 413 69.27 0.0 mol:protein length:413 Isocitrate Dehydrogenase
blastp_pdb 1lwd_A 2 428 + 427 Gaps:21 99.27 413 69.27 0.0 mol:protein length:413 Isocitrate Dehydrogenase
blastp_pdb 2cmv_B 12 429 + 418 Gaps:19 97.80 410 66.58 0.0 mol:protein length:410 ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC
blastp_pdb 2cmv_A 12 429 + 418 Gaps:19 97.80 410 66.58 0.0 mol:protein length:410 ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC
blastp_pdb 2cmj_B 12 429 + 418 Gaps:19 97.80 410 66.58 0.0 mol:protein length:410 ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC
blastp_pdb 2cmj_A 12 429 + 418 Gaps:19 97.80 410 66.58 0.0 mol:protein length:410 ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC
blastp_pdb 3us8_B 5 429 + 425 Gaps:26 93.91 427 69.83 0.0 mol:protein length:427 Isocitrate dehydrogenase [NADP]
blastp_pdb 3us8_A 5 429 + 425 Gaps:26 93.91 427 69.83 0.0 mol:protein length:427 Isocitrate dehydrogenase [NADP]
blastp_pdb 1t0l_D 12 429 + 418 Gaps:19 96.86 414 66.33 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t0l_C 12 429 + 418 Gaps:19 96.86 414 66.33 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_uniprot_sprot sp|P50218|IDHC_TOBAC 1 428 + 428 Gaps:18 98.80 415 89.51 0.0 Isocitrate dehydrogenase [NADP] OS Nicotiana tabacum PE 2 SV 1
blastp_uniprot_sprot sp|P50217|IDHC_SOLTU 1 428 + 428 Gaps:19 98.80 416 89.54 0.0 Isocitrate dehydrogenase [NADP] OS Solanum tuberosum GN ICDH-1 PE 2 SV 1
blastp_uniprot_sprot sp|Q06197|IDHC_SOYBN 2 429 + 428 Gaps:18 99.27 413 89.27 0.0 Isocitrate dehydrogenase [NADP] OS Glycine max GN IDH1 PE 1 SV 2
blastp_uniprot_sprot sp|Q40345|IDHP_MEDSA 1 429 + 429 Gaps:18 94.92 433 88.56 0.0 Isocitrate dehydrogenase [NADP] chloroplastic (Fragment) OS Medicago sativa PE 1 SV 1
blastp_uniprot_sprot sp|Q9SRZ6|ICDHC_ARATH 1 429 + 429 Gaps:20 99.76 410 89.98 0.0 Cytosolic isocitrate dehydrogenase [NADP] OS Arabidopsis thaliana GN CICDH PE 2 SV 1
blastp_uniprot_sprot sp|Q9SLK0|ICDHX_ARATH 1 428 + 428 Gaps:19 98.32 416 87.29 0.0 Peroxisomal isocitrate dehydrogenase [NADP] OS Arabidopsis thaliana GN ICDH PE 1 SV 1
blastp_uniprot_sprot sp|Q8LPJ5|ICDHP_ARATH 4 428 + 425 Gaps:19 83.71 485 79.80 0.0 Isocitrate dehydrogenase [NADP] chloroplastic/mitochondrial OS Arabidopsis thaliana GN At5g14590 PE 1 SV 1
blastp_uniprot_sprot sp|P33198|IDHP_PIG 2 428 + 427 Gaps:21 97.39 421 69.27 0.0 Isocitrate dehydrogenase [NADP] mitochondrial (Fragment) OS Sus scrofa GN IDH2 PE 1 SV 1
blastp_uniprot_sprot sp|P54071|IDHP_MOUSE 2 428 + 427 Gaps:21 90.71 452 69.27 0.0 Isocitrate dehydrogenase [NADP] mitochondrial OS Mus musculus GN Idh2 PE 1 SV 3
blastp_uniprot_sprot sp|Q4R502|IDHP_MACFA 2 428 + 427 Gaps:21 90.71 452 69.51 0.0 Isocitrate dehydrogenase [NADP] mitochondrial OS Macaca fascicularis GN IDH2 PE 2 SV 1

10 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 247 247 PTHR11822 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268";signature_desc=NADP-SPECIFIC ISOCITRATE DEHYDROGENASE none IPR004790
PANTHER 266 429 164 PTHR11822 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268";signature_desc=NADP-SPECIFIC ISOCITRATE DEHYDROGENASE none IPR004790
TIGRFAM 5 429 425 TIGR00127 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268" nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent IPR004790
Pfam 7 420 414 PF00180 none Isocitrate/isopropylmalate dehydrogenase IPR024084
Coils 238 245 8 Coil none none none
Gene3D 4 427 424 G3DSA:3.40.718.10 none none IPR024084
ProSitePatterns 291 310 20 PS00470 "Reactome:REACT_1046" Isocitrate and isopropylmalate dehydrogenases signature. IPR019818
Coils 266 270 5 Coil none none none
SUPERFAMILY 3 428 426 SSF53659 none none none
PIRSF 1 430 430 PIRSF000108 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268" none IPR004790

0 Localization

9 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran_2000_2002_QTL2_Delta.F Qrob_Chr02 2 s_1CSO13_1244 s_1AVEUF_1540 55.44 46,71 63,68 lod 7.3232 0.058
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03

0 Targeting