Protein : Qrob_P0284250.2 Q. robur
Protein Identifier  ? Qrob_P0284250.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) 1.1.1.42 - Isocitrate dehydrogenase (NADP(+)). Code Enzyme  EC:1.1.1.42
Gene Prediction Quality  validated Protein length 

Sequence

Length: 417  
Kegg Orthology  K00031
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0051287 NAD binding Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
GO:0004450 isocitrate dehydrogenase (NADP+) activity Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.
GO:0006102 isocitrate metabolic process The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.
GO:0000287 magnesium ion binding Interacting selectively and non-covalently with magnesium (Mg) ions.

40 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cit:102609279 1 414 + 414 none 100.00 414 90.82 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|pper:PRUPE_ppa006334mg 3 416 + 414 none 99.28 417 90.10 0.0 hypothetical protein
blastp_kegg lcl|fve:101303399 2 416 + 415 none 99.52 417 89.88 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|pop:POPTR_0004s07320g 1 414 + 414 none 100.00 414 90.34 0.0 POPTRDRAFT_648243 isocitrate dehydrogenase family protein
blastp_kegg lcl|pmum:103325562 3 416 + 414 none 99.28 417 89.86 0.0 isocitrate dehydrogenase [NADP]
blastp_kegg lcl|rcu:RCOM_0113200 1 411 + 411 none 99.52 413 91.24 0.0 NADP-specific isocitrate dehydrogenase putative (EC:1.1.1.42)
blastp_kegg lcl|pop:POPTR_0010s18360g 1 416 + 416 none 97.20 428 89.66 0.0 POPTRDRAFT_770098 NADP-dependent isocitrate dehydrogenase family protein
blastp_kegg lcl|vvi:100243260 1 416 + 416 none 100.00 416 89.18 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|mdm:103435343 2 416 + 415 none 86.46 480 89.16 0.0 isocitrate dehydrogenase [NADP]-like
blastp_kegg lcl|cic:CICLE_v10001314mg 1 414 + 414 none 100.00 414 90.10 0.0 hypothetical protein
blastp_pdb 1lwd_B 4 410 + 407 Gaps:3 98.79 413 70.10 0.0 mol:protein length:413 Isocitrate Dehydrogenase
blastp_pdb 1lwd_A 4 410 + 407 Gaps:3 98.79 413 70.10 0.0 mol:protein length:413 Isocitrate Dehydrogenase
blastp_pdb 1t0l_D 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t0l_C 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t0l_B 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t0l_A 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t09_B 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 1t09_A 12 416 + 405 Gaps:2 97.83 414 69.38 0.0 mol:protein length:414 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 3mas_B 12 416 + 405 Gaps:2 96.66 419 69.38 0.0 mol:protein length:419 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_pdb 3inm_C 12 416 + 405 Gaps:2 95.29 425 69.14 0.0 mol:protein length:425 Isocitrate dehydrogenase [NADP] cytoplasmic
blastp_uniprot_sprot sp|P50218|IDHC_TOBAC 1 410 + 410 none 98.80 415 87.80 0.0 Isocitrate dehydrogenase [NADP] OS Nicotiana tabacum PE 2 SV 1
blastp_uniprot_sprot sp|P50217|IDHC_SOLTU 1 410 + 410 Gaps:1 98.80 416 87.10 0.0 Isocitrate dehydrogenase [NADP] OS Solanum tuberosum GN ICDH-1 PE 2 SV 1
blastp_uniprot_sprot sp|Q06197|IDHC_SOYBN 2 411 + 410 none 99.27 413 87.07 0.0 Isocitrate dehydrogenase [NADP] OS Glycine max GN IDH1 PE 1 SV 2
blastp_uniprot_sprot sp|Q40345|IDHP_MEDSA 1 411 + 411 none 94.92 433 86.62 0.0 Isocitrate dehydrogenase [NADP] chloroplastic (Fragment) OS Medicago sativa PE 1 SV 1
blastp_uniprot_sprot sp|Q9SLK0|ICDHX_ARATH 1 410 + 410 Gaps:1 98.32 416 87.04 0.0 Peroxisomal isocitrate dehydrogenase [NADP] OS Arabidopsis thaliana GN ICDH PE 1 SV 1
blastp_uniprot_sprot sp|Q9SRZ6|ICDHC_ARATH 1 411 + 411 Gaps:2 99.76 410 86.06 0.0 Cytosolic isocitrate dehydrogenase [NADP] OS Arabidopsis thaliana GN CICDH PE 2 SV 1
blastp_uniprot_sprot sp|Q8LPJ5|ICDHP_ARATH 2 410 + 409 Gaps:1 84.12 485 77.21 0.0 Isocitrate dehydrogenase [NADP] chloroplastic/mitochondrial OS Arabidopsis thaliana GN At5g14590 PE 1 SV 1
blastp_uniprot_sprot sp|P33198|IDHP_PIG 4 406 + 403 Gaps:3 95.96 421 70.54 0.0 Isocitrate dehydrogenase [NADP] mitochondrial (Fragment) OS Sus scrofa GN IDH2 PE 1 SV 1
blastp_uniprot_sprot sp|Q04467|IDHP_BOVIN 4 406 + 403 Gaps:3 89.38 452 70.30 0.0 Isocitrate dehydrogenase [NADP] mitochondrial OS Bos taurus GN IDH2 PE 1 SV 2
blastp_uniprot_sprot sp|Q9XSG3|IDHC_BOVIN 4 416 + 413 Gaps:3 99.52 414 69.42 0.0 Isocitrate dehydrogenase [NADP] cytoplasmic OS Bos taurus GN IDH1 PE 2 SV 1

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSitePatterns 273 292 20 PS00470 "Reactome:REACT_1046" Isocitrate and isopropylmalate dehydrogenases signature. IPR019818
SUPERFAMILY 3 410 408 SSF53659 none none none
PANTHER 1 416 416 PTHR11822 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268";signature_desc=NADP-SPECIFIC ISOCITRATE DEHYDROGENASE none IPR004790
Gene3D 4 409 406 G3DSA:3.40.718.10 none none IPR024084
TIGRFAM 4 411 408 TIGR00127 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268" nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent IPR004790
PIRSF 1 413 413 PIRSF000108 "KEGG:00020+1.1.1.42","KEGG:00480+1.1.1.42","KEGG:00720+1.1.1.42","MetaCyc:PWY-5913","MetaCyc:PWY-6549","MetaCyc:PWY-6728","MetaCyc:PWY-6969","MetaCyc:PWY-7124","MetaCyc:PWY-7254","MetaCyc:PWY-7268" none IPR004790
Pfam 7 402 396 PF00180 none Isocitrate/isopropylmalate dehydrogenase IPR024084

0 Localization

12 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2014_nPriLBD*_3P Qrob_Chr11 11 v_12066_307 s_1B15GJ_447 3,37 0,57 16,17 lod 3,4299 6,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2002_QTL16_peak_Bud_burst_A4 Qrob_Chr11 11 s_A9OIA_166 s_1C6WBF_114 21,23 2,83 42,83 lod 5,1 7,2
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Champenoux_2015_nSecLBD_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 25,78 25,47 27,72 lod 6.3 16.6
Bourran2_2014_nP_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 7,9 0,09 30,09 lod 2,3636 5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9
Bourran1_2003_QTL6_peak_Bud_burst_A4 Qrob_Chr11 11 v_12066_307 s_1A9FKZ_348 3,59 0 20,89 lod 3,4 9,4
PM_1999_QTL17_peak_Bud_burst_3P Qrob_Chr11 11 s_1A9FKZ_348 v_11486_883 4,8 0 24,8 lod 3,5 6,2
Bourran2_2014_vEpiBC*_3P Qrob_Chr11 11 s_1A5GRX_415 v_4456_500 9,37 0 19,27 lod 3,513 9,3
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL1_d13Cf Qrob_Chr11 11 s_1A9FKZ_348 v_7268_36 13.33 3,98 19,87 lod 29.1377 0.18

0 Targeting