Protein : Qrob_P0252880.2 Q. robur
Protein Identifier  ? Qrob_P0252880.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K02370 - alpha-1,4-N-acetylglucosaminyltransferase EXTL3 [EC:2.4.1.223 2.4.1.224] Code Enzyme  EC:2.4.1.223
Gene Prediction Quality  validated Protein length 

Sequence

Length: 330  
Kegg Orthology  K02370
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0006024 glycosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
GO:0015012 heparan sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103320132 7 329 + 323 Gaps:14 95.17 352 69.25 3e-164 exostosin-like 3
blastp_kegg lcl|mdm:103441199 1 329 + 329 Gaps:13 96.87 351 67.94 4e-164 exostosin-like 3
blastp_kegg lcl|pxb:103964512 1 329 + 329 Gaps:13 99.71 341 67.65 5e-163 exostosin-like 3
blastp_kegg lcl|fve:101310373 1 329 + 329 Gaps:15 100.00 342 68.71 1e-162 exostosin-like 3-like isoform 1
blastp_kegg lcl|rcu:RCOM_0476310 21 328 + 308 Gaps:8 89.97 349 71.97 1e-162 transferase transferring glycosyl groups putative (EC:2.4.1.223)
blastp_kegg lcl|pper:PRUPE_ppa008992mg 26 329 + 304 Gaps:8 99.68 311 70.97 2e-159 hypothetical protein
blastp_kegg lcl|mdm:103456066 1 329 + 329 Gaps:16 100.00 341 65.69 1e-158 exostosin-like 3
blastp_kegg lcl|cic:CICLE_v10010680mg 22 328 + 307 Gaps:5 91.45 339 70.97 2e-155 hypothetical protein
blastp_kegg lcl|cit:102619904 22 328 + 307 Gaps:5 88.07 352 70.97 5e-155 exostosin-like 3-like
blastp_kegg lcl|vvi:100245636 20 328 + 309 Gaps:11 93.29 328 67.65 2e-149 exostosin-1-like
blastp_pdb 1on8_B 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on8_A 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on6_B 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1on6_A 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omz_B 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omz_A 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omx_B 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_pdb 1omx_A 34 302 + 269 Gaps:42 87.03 293 28.63 4e-15 mol:protein length:293 Alpha-1 4-N-acetylhexosaminyltransferase EXTL
blastp_uniprot_sprot sp|Q9WVL6|EXTL3_MOUSE 39 307 + 269 Gaps:29 26.36 918 34.71 2e-28 Exostosin-like 3 OS Mus musculus GN Extl3 PE 2 SV 2
blastp_uniprot_sprot sp|O43909|EXTL3_HUMAN 42 307 + 266 Gaps:29 26.01 919 35.15 2e-28 Exostosin-like 3 OS Homo sapiens GN EXTL3 PE 1 SV 1
blastp_uniprot_sprot sp|O01705|EXT2_CAEEL 42 303 + 262 Gaps:32 28.50 814 33.62 2e-24 Exostosin-2 OS Caenorhabditis elegans GN rib-2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9XZ08|EXT3_DROME 42 300 + 259 Gaps:31 24.07 972 36.75 1e-23 Exostosin-3 OS Drosophila melanogaster GN botv PE 1 SV 1
blastp_uniprot_sprot sp|Q5IGR8|EXT1A_DANRE 57 300 + 244 Gaps:32 30.41 730 33.33 9e-21 Exostosin-1a OS Danio rerio GN ext1a PE 2 SV 1
blastp_uniprot_sprot sp|Q5IGR6|EXT1C_DANRE 57 302 + 246 Gaps:47 32.97 737 32.92 1e-20 Exostosin-1c OS Danio rerio GN ext1c PE 2 SV 1
blastp_uniprot_sprot sp|Q5IGR7|EXT1B_DANRE 57 300 + 244 Gaps:32 29.96 741 32.88 1e-19 Exostosin-1b OS Danio rerio GN ext1b PE 2 SV 1
blastp_uniprot_sprot sp|Q9JK82|EXT1_CRIGR 57 300 + 244 Gaps:28 29.76 746 33.33 3e-19 Exostosin-1 OS Cricetulus griseus GN EXT1 PE 1 SV 1
blastp_uniprot_sprot sp|Q16394|EXT1_HUMAN 57 300 + 244 Gaps:28 29.76 746 33.33 3e-19 Exostosin-1 OS Homo sapiens GN EXT1 PE 1 SV 2
blastp_uniprot_sprot sp|A5D7I4|EXT1_BOVIN 57 300 + 244 Gaps:28 29.76 746 33.78 4e-19 Exostosin-1 OS Bos taurus GN EXT1 PE 2 SV 1
rpsblast_cdd gnl|CDD|192236 44 308 + 265 Gaps:27 98.36 244 42.50 8e-71 pfam09258 Glyco_transf_64 Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate.
rpsblast_kog gnl|CDD|37475 42 302 + 261 Gaps:29 25.80 907 35.04 5e-33 KOG2264 KOG2264 KOG2264 Exostosin EXT1L [Signal transduction mechanisms].

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 20 329 310 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 102 302 201 PTHR11062 none none none
Phobius 7 15 9 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Phobius 1 6 6 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Gene3D 40 319 280 G3DSA:3.90.550.10 none none IPR029044
Phobius 1 19 19 SIGNAL_PEPTIDE none Signal peptide region none
Pfam 44 311 268 PF09258 none Glycosyl transferase family 64 domain IPR015338
Phobius 16 19 4 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
SUPERFAMILY 44 303 260 SSF53448 none none IPR029044

2 Localization

Analysis Start End Length
SignalP_EUK 1 19 18
TMHMM 7 24 17

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran2_2015_nSecLBD_3P Qrob_Chr12 12 s_A4YYC_633 s_2F1IZB_703 18,64 18,01 21,53 lod 6.5 17.2

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 19   Secretory pathway 2 0.847 0.094 NON-PLANT 19