Protein : Qrob_P0251500.2 Q. robur

Protein Identifier  ? Qrob_P0251500.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=23) KOG0252//KOG0253//KOG0254//KOG0255//KOG0569 - Inorganic phosphate transporter [Inorganic ion transport and metabolism]. // Synaptic vesicle transporter SV2 (major facilitator superfamily) [General function prediction only]. // Predicted transporter (major facilitator superfamily) [General function prediction only]. // Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily) [General function prediction only]. // Permease of the major facilitator superfamily [Carbohydrate transport and metabolism]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 738  

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

35 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa001957mg 1 727 + 727 Gaps:3 98.64 736 85.12 0.0 hypothetical protein
blastp_kegg lcl|pmum:103334621 1 727 + 727 Gaps:3 98.64 736 84.57 0.0 monosaccharide-sensing protein 2
blastp_kegg lcl|csv:101212786 1 736 + 736 Gaps:4 99.86 733 82.38 0.0 monosaccharide-sensing protein 2-like
blastp_kegg lcl|cmo:103490449 1 736 + 736 Gaps:4 99.86 733 82.24 0.0 monosaccharide-sensing protein 2
blastp_kegg lcl|rcu:RCOM_1386130 1 737 + 737 Gaps:7 100.00 740 84.05 0.0 sugar transporter putative (EC:1.3.1.74)
blastp_kegg lcl|pxb:103932878 1 737 + 737 Gaps:3 100.00 736 81.66 0.0 monosaccharide-sensing protein 2-like
blastp_kegg lcl|pxb:103926706 1 727 + 727 Gaps:3 98.64 736 83.06 0.0 monosaccharide-sensing protein 2-like
blastp_kegg lcl|pop:POPTR_0009s16960g 1 737 + 737 Gaps:7 100.00 740 82.57 0.0 POPTRDRAFT_1085904 transporter-related family protein
blastp_kegg lcl|pxb:103933526 1 727 + 727 Gaps:3 98.64 736 82.78 0.0 monosaccharide-sensing protein 2-like
blastp_kegg lcl|pvu:PHAVU_009G115500g 1 735 + 735 Gaps:10 99.46 739 80.14 0.0 hypothetical protein
blastp_uniprot_sprot sp|Q8LPQ8|MSSP2_ARATH 1 737 + 737 Gaps:21 99.86 729 78.71 0.0 Monosaccharide-sensing protein 2 OS Arabidopsis thaliana GN MSSP2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9SD00|MSSP3_ARATH 1 730 + 730 Gaps:60 98.49 729 67.69 0.0 Monosaccharide-sensing protein 3 OS Arabidopsis thaliana GN MSSP3 PE 2 SV 1
blastp_uniprot_sprot sp|Q96290|MSSP1_ARATH 1 732 + 732 Gaps:35 99.05 734 64.92 0.0 Monosaccharide-sensing protein 1 OS Arabidopsis thaliana GN MSSP1 PE 1 SV 2
blastp_uniprot_sprot sp|Q9ZQP6|INT3_ARATH 7 737 + 731 Gaps:19 74.66 580 37.41 2e-37 Probable inositol transporter 3 OS Arabidopsis thaliana GN INT3 PE 2 SV 1
blastp_uniprot_sprot sp|C0SPB2|YWTG_BACSU 12 722 + 711 Gaps:25 92.78 457 35.85 8e-36 Putative metabolite transport protein YwtG OS Bacillus subtilis (strain 168) GN ywtG PE 3 SV 1
blastp_uniprot_sprot sp|O23492|INT4_ARATH 7 729 + 723 Gaps:17 72.68 582 37.83 8e-35 Inositol transporter 4 OS Arabidopsis thaliana GN INT4 PE 1 SV 1
blastp_uniprot_sprot sp|Q9C757|INT2_ARATH 7 722 + 716 Gaps:16 69.66 580 39.36 3e-34 Probable inositol transporter 2 OS Arabidopsis thaliana GN INT2 PE 1 SV 1
blastp_uniprot_sprot sp|P94493|YNCC_BACSU 6 724 + 719 Gaps:16 94.06 471 32.28 2e-32 Putative metabolite transport protein YncC OS Bacillus subtilis (strain 168) GN yncC PE 3 SV 2
blastp_uniprot_sprot sp|Q96QE2|MYCT_HUMAN 6 724 + 719 Gaps:14 61.42 648 35.68 3e-32 Proton myo-inositol cotransporter OS Homo sapiens GN SLC2A13 PE 1 SV 3
blastp_uniprot_sprot sp|Q8VZ80|PLT5_ARATH 4 725 + 722 Gaps:39 85.16 539 32.90 4e-32 Polyol transporter 5 OS Arabidopsis thaliana GN PLT5 PE 1 SV 2
rpsblast_cdd gnl|CDD|200987 7 724 + 718 Gaps:27 98.44 449 33.48 1e-42 pfam00083 Sugar_tr Sugar (and other) transporter.
rpsblast_cdd gnl|CDD|162084 4 720 + 717 Gaps:27 94.80 481 36.18 3e-38 TIGR00879 SP MFS transporter sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083).
rpsblast_cdd gnl|CDD|182225 7 718 + 712 Gaps:45 92.28 479 31.00 2e-30 PRK10077 xylE D-xylose transporter XylE Provisional.
rpsblast_cdd gnl|CDD|162097 53 209 + 157 Gaps:14 29.11 505 37.41 2e-21 TIGR00898 2A0119 cation transport protein.
rpsblast_cdd gnl|CDD|119392 9 710 + 702 Gaps:44 98.86 352 38.79 5e-20 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
rpsblast_cdd gnl|CDD|191813 12 713 + 702 Gaps:25 50.87 346 41.48 1e-14 pfam07690 MFS_1 Major Facilitator Superfamily.
rpsblast_cdd gnl|CDD|130366 46 208 + 163 Gaps:25 22.91 742 35.29 2e-13 TIGR01299 synapt_SV2 synaptic vesicle protein SV2. This model describes a tightly conserved subfamily of the larger family of sugar (and other) transporters described by PFAM HMM pfam00083. Members of this subfamily include closely related forms SV2A and SV2B of synaptic vesicle protein from vertebrates and a more distantly related homolog (below trusted cutoff) from Drosophila melanogaster. Members are predicted to have two sets of six transmembrane helices.
rpsblast_cdd gnl|CDD|162095 6 204 + 199 Gaps:16 48.99 398 29.74 3e-13 TIGR00895 2A0115 benzoate transport.
rpsblast_cdd gnl|CDD|188094 14 189 + 176 Gaps:28 49.24 394 22.68 1e-10 TIGR00883 2A0106 metabolite-proton symporter. This model represents the metabolite:H+ symport subfamily of the major facilitator superfamily (pfam00083) including citrate-H+ symporters dicarboxylate:H+ symporters the proline/glycine-betaine transporter ProP etc.
rpsblast_cdd gnl|CDD|162085 46 188 + 143 Gaps:18 100.00 141 30.50 1e-10 TIGR00880 2_A_01_02 Multidrug resistance protein.

43 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 19 19 SIGNAL_PEPTIDE none Signal peptide region none
Phobius 592 613 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 43 67 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 243 249 7 PTHR24063 none none none
Phobius 658 678 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 581 591 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
ProSitePatterns 63 80 18 PS00216 none Sugar transport proteins signature 1. IPR005829
Phobius 3 14 12 SIGNAL_PEPTIDE_H_REGION none Hydrophobic region of a signal peptide. none
Phobius 165 185 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 122 164 43 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 1 2 2 SIGNAL_PEPTIDE_N_REGION none N-terminal region of a signal peptide. none
Phobius 74 92 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 494 718 225 SSF103473 none none IPR020846
SUPERFAMILY 6 212 207 SSF103473 none none IPR020846
Phobius 20 42 23 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
ProSitePatterns 105 130 26 PS00217 none Sugar transport proteins signature 2. IPR005829
Phobius 15 19 5 SIGNAL_PEPTIDE_C_REGION none C-terminal region of a signal peptide. none
Gene3D 10 189 180 G3DSA:1.20.1250.20 none none none
Gene3D 520 715 196 G3DSA:1.20.1250.20 none none none
Phobius 679 683 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 186 560 375 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PRINTS 625 646 22 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 648 660 13 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 15 25 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 100 119 20 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 526 536 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
Phobius 98 121 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
ProSiteProfiles 7 713 707 PS50850 none Major facilitator superfamily (MFS) profile. IPR020846
Pfam 7 219 213 PF00083 none Sugar (and other) transporter IPR005828
Pfam 502 722 221 PF00083 none Sugar (and other) transporter IPR005828

11 Localization

Analysis Start End Length
TMHMM 10 32 22
TMHMM 44 66 22
TMHMM 658 680 22
TMHMM 165 187 22
TMHMM 685 707 22
TMHMM 562 584 22
TMHMM 623 645 22
TMHMM 99 121 22
TMHMM 136 158 22
TMHMM 70 92 22
TMHMM 591 613 22

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 19   Secretory pathway 2 0.848 0.048 NON-PLANT 19