GO:0005524
|
ATP binding
|
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
GO:0005634
|
nucleus
|
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
GO:0003682
|
chromatin binding
|
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
GO:0006270
|
DNA replication initiation
|
The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action. |
GO:0003678
|
DNA helicase activity
|
Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix. |
GO:0042555
|
MCM complex
|
A hexameric protein complex required for the initiation and regulation of DNA replication. |
GO:0003688
|
DNA replication origin binding
|
Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. |