Protein : Qrob_P0240720.2 Q. robur
Protein Identifier  ? Qrob_P0240720.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) 1.5.1.5 - Methylenetetrahydrofolate dehydrogenase (NADP(+)). Code Enzyme  EC:3.5.4.9, EC:1.5.1.5
Gene Prediction Quality  validated Protein length 

Sequence

Length: 366  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.
GO:0009396 folic acid-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_017732 6 364 + 359 Gaps:3 96.76 370 74.86 0.0 Amino acid dehydrogenase family protein isoform 1
blastp_kegg lcl|fve:101291841 5 365 + 361 Gaps:9 99.18 365 74.31 0.0 c-1-tetrahydrofolate synthase cytoplasmic-like
blastp_kegg lcl|vvi:100250136 10 365 + 356 Gaps:8 99.72 355 76.27 0.0 bifunctional protein FolD-like
blastp_kegg lcl|pxb:103960158 6 365 + 360 Gaps:6 98.91 366 74.59 0.0 bifunctional protein FolD 1 mitochondrial
blastp_kegg lcl|mdm:103433804 6 365 + 360 Gaps:6 98.91 366 74.31 0.0 bifunctional protein FolD 1 mitochondrial
blastp_kegg lcl|pmum:103342355 18 365 + 348 Gaps:5 96.19 367 74.50 0.0 bifunctional protein FolD 1 mitochondrial
blastp_kegg lcl|cit:102625176 15 365 + 351 Gaps:15 96.74 368 74.44 0.0 bifunctional protein FolD 1 mitochondrial-like
blastp_kegg lcl|pper:PRUPE_ppa007447mg 6 365 + 360 Gaps:7 98.91 367 73.55 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1323540 5 364 + 360 Gaps:24 96.09 358 77.33 0.0 methylenetetrahydrofolate dehydrogenase putative (EC:3.5.4.9)
blastp_kegg lcl|cmo:103501504 31 364 + 334 none 86.53 386 76.05 0.0 bifunctional protein FolD 1 mitochondrial
blastp_pdb 4a26_B 73 361 + 289 Gaps:3 97.33 300 52.05 9e-95 mol:protein length:300 PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE CYTOP
blastp_pdb 4a26_A 73 361 + 289 Gaps:3 97.33 300 52.05 9e-95 mol:protein length:300 PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE CYTOP
blastp_pdb 4a5o_D 73 363 + 291 Gaps:8 98.95 286 50.88 5e-84 mol:protein length:286 BIFUNCTIONAL PROTEIN FOLD
blastp_pdb 4a5o_C 73 363 + 291 Gaps:8 98.95 286 50.88 5e-84 mol:protein length:286 BIFUNCTIONAL PROTEIN FOLD
blastp_pdb 4a5o_B 73 363 + 291 Gaps:8 98.95 286 50.88 5e-84 mol:protein length:286 BIFUNCTIONAL PROTEIN FOLD
blastp_pdb 4a5o_A 73 363 + 291 Gaps:8 98.95 286 50.88 5e-84 mol:protein length:286 BIFUNCTIONAL PROTEIN FOLD
blastp_pdb 1a4i_B 74 360 + 287 Gaps:3 96.35 301 46.21 2e-83 mol:protein length:301 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / MET
blastp_pdb 1a4i_A 74 360 + 287 Gaps:3 96.35 301 46.21 2e-83 mol:protein length:301 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / MET
blastp_pdb 1dig_B 74 360 + 287 Gaps:3 94.77 306 46.21 3e-83 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYC
blastp_pdb 1dig_A 74 360 + 287 Gaps:3 94.77 306 46.21 3e-83 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYC
blastp_uniprot_sprot sp|A2RVV7|FOLD1_ARATH 23 362 + 340 Gaps:7 94.60 352 69.07 9e-166 Bifunctional protein FolD 1 mitochondrial OS Arabidopsis thaliana GN FOLD1 PE 1 SV 1
blastp_uniprot_sprot sp|O65271|FOLD4_ARATH 74 364 + 291 none 80.83 360 69.76 6e-147 Bifunctional protein FolD 4 chloroplastic OS Arabidopsis thaliana GN FOLD4 PE 1 SV 1
blastp_uniprot_sprot sp|Q9LHH7|FOLD2_ARATH 69 362 + 294 none 98.33 299 61.56 4e-129 Bifunctional protein FolD 2 OS Arabidopsis thaliana GN FOLD2 PE 1 SV 1
blastp_uniprot_sprot sp|O65269|FOLD3_ARATH 74 364 + 291 Gaps:36 82.26 310 66.67 1e-112 Bifunctional protein FolD 3 chloroplastic OS Arabidopsis thaliana GN FOLD3 PE 3 SV 1
blastp_uniprot_sprot sp|Q8Y7C5|FOLD_LISMO 76 362 + 287 Gaps:9 97.89 284 53.96 3e-98 Bifunctional protein FolD OS Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|B8DFW8|FOLD_LISMH 76 362 + 287 Gaps:9 97.89 284 53.96 1e-97 Bifunctional protein FolD OS Listeria monocytogenes serotype 4a (strain HCC23) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|C1L2R6|FOLD_LISMC 76 362 + 287 Gaps:9 97.89 284 53.60 1e-97 Bifunctional protein FolD OS Listeria monocytogenes serotype 4b (strain CLIP80459) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|Q71ZW2|FOLD_LISMF 76 362 + 287 Gaps:9 97.89 284 53.60 4e-97 Bifunctional protein FolD OS Listeria monocytogenes serotype 4b (strain F2365) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|Q92BZ4|FOLD_LISIN 76 362 + 287 Gaps:9 97.89 284 53.60 2e-96 Bifunctional protein FolD OS Listeria innocua serovar 6a (strain CLIP 11262) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|A0AIG1|FOLD_LISW6 76 362 + 287 Gaps:9 97.89 284 53.24 6e-92 Bifunctional protein FolD OS Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334) GN folD PE 3 SV 1

15 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 213 343 131 G3DSA:3.40.50.720 none none IPR016040
Pfam 195 361 167 PF02882 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IPR020631
ProSitePatterns 339 347 9 PS00767 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. IPR020867
PRINTS 146 173 28 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 318 334 17 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 105 127 23 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 277 306 30 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 228 248 21 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 181 202 22 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 335 353 19 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
Gene3D 78 212 135 G3DSA:3.40.192.10 none none none
SUPERFAMILY 74 193 120 SSF53223 none none none
SUPERFAMILY 194 360 167 SSF51735 none none none
PANTHER 44 362 319 PTHR10025 none none none
Pfam 76 192 117 PF00763 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IPR020630

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Bourran2_2014_nEpiBC_A4 Qrob_Chr07 7 s_2FI9D9_500 s_1AXDMJ_325 12,26 0 34,9 lod 2,2306 6,1

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 27   Mitochondrion 2 0.102 0.745 NON-PLANT 27