Protein : Qrob_P0201490.2 Q. robur
Protein Identifier  ? Qrob_P0201490.2 Organism . Name  Quercus robur
Score  98.0 Score Type  egn
Protein Description  (M=1) 6.3.5.3 - Phosphoribosylformylglycinamidine synthase. Code Enzyme  EC:6.3.5.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1412  
Kegg Orthology  K01952
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0006189 'de novo' IMP biosynthetic process The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
GO:0004642 phosphoribosylformylglycinamidine synthase activity Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa000243mg 1 1411 + 1411 Gaps:1 100.00 1412 87.75 0.0 hypothetical protein
blastp_kegg lcl|pxb:103960355 1 1411 + 1411 Gaps:1 100.00 1412 87.04 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_kegg lcl|pxb:103960350 1 1411 + 1411 Gaps:1 100.00 1412 87.04 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_kegg lcl|pxb:103960346 1 1411 + 1411 Gaps:1 100.00 1412 86.83 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_kegg lcl|pxb:103962592 1 1411 + 1411 Gaps:3 100.00 1414 86.92 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_kegg lcl|tcc:TCM_022107 1 1411 + 1411 Gaps:1 100.00 1412 86.26 0.0 Purine biosynthesis 4
blastp_kegg lcl|cit:102627776 1 1411 + 1411 Gaps:3 100.00 1414 85.93 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial-like
blastp_kegg lcl|cic:CICLE_v10030516mg 1 1411 + 1411 Gaps:3 100.00 1414 86.00 0.0 hypothetical protein
blastp_kegg lcl|pmum:103319406 1 1411 + 1411 Gaps:1 100.00 1410 86.81 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_kegg lcl|pmum:103336398 12 1411 + 1400 none 100.00 1400 87.43 0.0 probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial
blastp_pdb 1t3t_A 178 1408 + 1231 Gaps:53 93.32 1303 40.13 0.0 mol:protein length:1303 Phosphoribosylformylglycinamidine synthase
blastp_pdb 3viu_A 392 1062 + 671 Gaps:83 84.14 725 26.56 3e-21 mol:protein length:725 Phosphoribosylformylglycinamidine synthase 2
blastp_pdb 3d54_L 1141 1375 + 235 Gaps:51 88.26 213 32.98 9e-15 mol:protein length:213 Phosphoribosylformylglycinamidine synthase 1
blastp_pdb 3d54_H 1141 1375 + 235 Gaps:51 88.26 213 32.98 9e-15 mol:protein length:213 Phosphoribosylformylglycinamidine synthase 1
blastp_pdb 3d54_D 1141 1375 + 235 Gaps:51 88.26 213 32.98 9e-15 mol:protein length:213 Phosphoribosylformylglycinamidine synthase 1
blastp_pdb 3d54_I 389 734 + 346 Gaps:59 48.81 629 29.32 6e-12 mol:protein length:629 Phosphoribosylformylglycinamidine synthase II
blastp_pdb 3d54_E 389 734 + 346 Gaps:59 48.81 629 29.32 6e-12 mol:protein length:629 Phosphoribosylformylglycinamidine synthase II
blastp_pdb 3d54_A 389 734 + 346 Gaps:59 48.81 629 29.32 6e-12 mol:protein length:629 Phosphoribosylformylglycinamidine synthase II
blastp_pdb 2hs4_A 389 734 + 346 Gaps:59 50.91 603 29.32 7e-12 mol:protein length:603 Phosphoribosylformylglycinamidine synthase II
blastp_pdb 2hs3_A 389 734 + 346 Gaps:59 50.91 603 29.32 7e-12 mol:protein length:603 Phosphoribosylformylglycinamidine synthase II
blastp_uniprot_sprot sp|Q9M8D3|PUR4_ARATH 1 1409 + 1409 Gaps:10 99.72 1407 81.18 0.0 Probable phosphoribosylformylglycinamidine synthase chloroplastic/mitochondrial OS Arabidopsis thaliana GN At1g74260 PE 2 SV 3
blastp_uniprot_sprot sp|Q54JC8|PUR4_DICDI 90 1410 + 1321 Gaps:68 99.56 1355 52.93 0.0 Phosphoribosylformylglycinamidine synthase OS Dictyostelium discoideum GN purL PE 1 SV 1
blastp_uniprot_sprot sp|O15067|PUR4_HUMAN 90 1409 + 1320 Gaps:31 99.33 1338 51.54 0.0 Phosphoribosylformylglycinamidine synthase OS Homo sapiens GN PFAS PE 1 SV 4
blastp_uniprot_sprot sp|Q5SUR0|PUR4_MOUSE 90 1409 + 1320 Gaps:32 99.33 1337 51.13 0.0 Phosphoribosylformylglycinamidine synthase OS Mus musculus GN Pfas PE 2 SV 1
blastp_uniprot_sprot sp|P35421|PUR4_DROME 119 1410 + 1292 Gaps:61 97.42 1354 47.31 0.0 Phosphoribosylformylglycinamidine synthase OS Drosophila melanogaster GN ade2 PE 1 SV 2
blastp_uniprot_sprot sp|Q19311|PUR4_CAEEL 94 1410 + 1317 Gaps:91 99.70 1324 46.74 0.0 Probable phosphoribosylformylglycinamidine synthase OS Caenorhabditis elegans GN F10F2.2 PE 3 SV 3
blastp_uniprot_sprot sp|P74881|PUR4_SALTY 178 1408 + 1231 Gaps:53 93.90 1295 40.13 0.0 Phosphoribosylformylglycinamidine synthase OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN purL PE 1 SV 3
blastp_uniprot_sprot sp|Q3IHZ2|PUR4_PSEHT 175 1408 + 1234 Gaps:65 94.21 1296 40.05 0.0 Phosphoribosylformylglycinamidine synthase OS Pseudoalteromonas haloplanktis (strain TAC 125) GN purL PE 3 SV 1
blastp_uniprot_sprot sp|Q57LE6|PUR4_SALCH 178 1408 + 1231 Gaps:53 93.90 1295 40.05 0.0 Phosphoribosylformylglycinamidine synthase OS Salmonella choleraesuis (strain SC-B67) GN purL PE 3 SV 3
blastp_uniprot_sprot sp|Q8Z4L6|PUR4_SALTI 118 1408 + 1291 Gaps:65 97.61 1295 39.48 0.0 Phosphoribosylformylglycinamidine synthase OS Salmonella typhi GN purL PE 3 SV 3

19 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 1141 1410 270 PF13507 none CobB/CobQ-like glutamine amidotransferase domain none
PANTHER 87 1411 1325 PTHR10099 none none none
SUPERFAMILY 740 922 183 SSF55326 none none IPR016188
SUPERFAMILY 91 249 159 SSF82697 none none none
SUPERFAMILY 531 765 235 SSF56042 none none IPR010918
SUPERFAMILY 1140 1410 271 SSF52317 none none IPR029062
TIGRFAM 94 1409 1316 TIGR01735 "KEGG:00230+6.3.5.3","MetaCyc:PWY-6121","MetaCyc:PWY-6122","MetaCyc:PWY-6277","UniPathway:UPA00074" FGAM_synt: phosphoribosylformylglycinamidine synthase IPR010073
SUPERFAMILY 322 529 208 SSF55326 none none IPR016188
PANTHER 87 1411 1325 PTHR10099:SF1 none none none
SUPERFAMILY 928 1114 187 SSF56042 none none IPR010918
Gene3D 757 914 158 G3DSA:3.30.1330.10 none none IPR016188
Gene3D 313 522 210 G3DSA:3.30.1330.10 none none IPR016188
Pfam 385 493 109 PF00586 none AIR synthase related protein, N-terminal domain IPR000728
ProSiteProfiles 1143 1387 245 PS51273 "Reactome:REACT_1698" Glutamine amidotransferase type 1 domain profile. IPR017926
Gene3D 1141 1410 270 G3DSA:3.40.50.880 none none IPR029062
Pfam 534 687 154 PF02769 none AIR synthase related protein, C-terminal domain IPR010918
Pfam 941 1073 133 PF02769 none AIR synthase related protein, C-terminal domain IPR010918
SUPERFAMILY 254 321 68 SSF109736 none none none
Hamap 90 1411 1322 MF_00419 "KEGG:00230+6.3.5.3","MetaCyc:PWY-6121","MetaCyc:PWY-6122","MetaCyc:PWY-6277","UniPathway:UPA00074" Phosphoribosylformylglycinamidine synthase [purL]. IPR010073

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9

0 Targeting