Protein : Qrob_P0170620.2 Q. robur
Protein Identifier  ? Qrob_P0170620.2 Organism . Name  Quercus robur
Score  92.1 Score Type  egn
Protein Description  (M=1) K04710 - Acyl-CoA-dependent ceramide synthase [EC:2.3.1.24] Gene Prediction Quality  validated
Protein length 

Sequence

Length: 326  
Kegg Orthology  K04710
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005783 endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

24 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103942228 1 303 + 303 Gaps:25 97.92 288 76.60 2e-147 LAG1 longevity assurance homolog 2-like
blastp_kegg lcl|pxb:103941039 1 305 + 305 Gaps:25 98.61 288 75.35 2e-147 LAG1 longevity assurance homolog 2-like
blastp_kegg lcl|tcc:TCM_007062 4 305 + 302 Gaps:25 97.23 289 74.73 1e-146 Longevity assurance factor putative
blastp_kegg lcl|mdm:103436493 1 305 + 305 Gaps:25 98.61 288 75.35 4e-146 LAG1 longevity assurance homolog 2
blastp_kegg lcl|pper:PRUPE_ppa009536mg 1 303 + 303 Gaps:25 97.92 288 76.24 1e-144 hypothetical protein
blastp_kegg lcl|pmum:103335271 1 303 + 303 Gaps:25 97.92 288 76.24 4e-144 LAG1 longevity assurance homolog 2
blastp_kegg lcl|pmum:103335305 1 313 + 313 Gaps:29 90.80 326 73.99 2e-142 LAG1 longevity assurance homolog 2-like
blastp_kegg lcl|fve:101294739 1 302 + 302 Gaps:25 97.57 288 74.02 2e-141 LAG1 longevity assurance homolog 2-like
blastp_kegg lcl|cmo:103495235 2 304 + 303 Gaps:25 97.58 289 74.11 2e-136 LAG1 longevity assurance homolog 2
blastp_kegg lcl|csv:101205881 2 304 + 303 Gaps:25 97.58 289 73.40 2e-135 LAG1 longevity assurance homolog 2-like
blastp_uniprot_sprot sp|Q9LJK3|LAG12_ARATH 1 303 + 303 Gaps:32 97.64 296 64.71 2e-127 LAG1 longevity assurance homolog 2 OS Arabidopsis thaliana GN LAG2 PE 1 SV 1
blastp_uniprot_sprot sp|Q84QC0|ASCL3_ORYSJ 7 303 + 297 Gaps:24 96.83 284 58.55 6e-106 ASC1-like protein 3 OS Oryza sativa subsp. japonica GN Os03g0264000 PE 2 SV 1
blastp_uniprot_sprot sp|Q6NQI8|LAG13_ARATH 5 303 + 299 Gaps:36 93.18 308 48.78 1e-73 LAG1 longevity assurance homolog 3 OS Arabidopsis thaliana GN At1g13580 PE 2 SV 2
blastp_uniprot_sprot sp|Q6EUN0|ASCL1_ORYSJ 5 303 + 299 Gaps:41 91.91 309 47.89 1e-68 ASC1-like protein 1 OS Oryza sativa subsp. japonica GN Os02g0581300 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LDF2|LAG11_ARATH 21 303 + 283 Gaps:35 87.74 310 46.32 2e-68 LAG1 longevity assurance homolog 1 OS Arabidopsis thaliana GN LAG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8W4Y5|ASCL_SOLLC 13 303 + 291 Gaps:35 91.09 303 45.65 2e-64 ASC1-like protein OS Solanum lycopersicum PE 2 SV 1
blastp_uniprot_sprot sp|Q6YWS8|ASCL2_ORYSJ 8 311 + 304 Gaps:48 99.01 303 44.67 5e-64 ASC1-like protein 2 OS Oryza sativa subsp. japonica GN Os02g0728300 PE 3 SV 2
blastp_uniprot_sprot sp|Q9M6A3|ASC1_SOLLC 29 303 + 275 Gaps:30 84.74 308 44.83 2e-48 Protein ASC1 OS Solanum lycopersicum GN Asc-1 PE 2 SV 2
blastp_uniprot_sprot sp|Q96G23|CERS2_HUMAN 61 305 + 245 Gaps:37 56.84 380 37.50 2e-27 Ceramide synthase 2 OS Homo sapiens GN CERS2 PE 1 SV 1
blastp_uniprot_sprot sp|Q924Z4|CERS2_MOUSE 61 305 + 245 Gaps:35 56.84 380 36.57 4e-27 Ceramide synthase 2 OS Mus musculus GN Cers2 PE 1 SV 1
rpsblast_cdd gnl|CDD|128963 65 292 + 228 Gaps:30 99.51 205 35.78 8e-28 smart00724 TLC TRAM LAG1 and CLN8 homology domains. Protein domain with at least 5 transmembrane alpha-helices. Lag1p and Lac1p are essential for acyl-CoA-dependent ceramide synthesis TRAM is a subunit of the translocon and the CLN8 gene is mutated in Northern epilepsy syndrome. The family may possess multiple functions such as lipid trafficking metabolism or sensing. Trh homologues possess additional homeobox domains.
rpsblast_cdd gnl|CDD|202771 65 284 + 220 Gaps:29 99.49 198 31.98 2e-27 pfam03798 TRAM_LAG1_CLN8 TLC domain.
rpsblast_cdd gnl|CDD|34663 19 305 + 287 Gaps:44 65.57 395 28.19 4e-18 COG5058 LAG1 Protein transporter of the TRAM (translocating chain-associating membrane) superfamily longevity assurance factor [Intracellular trafficking and secretion].
rpsblast_kog gnl|CDD|36820 11 303 + 293 Gaps:27 83.65 318 40.23 9e-51 KOG1607 KOG1607 KOG1607 Protein transporter of the TRAM (translocating chain-associating membrane) superfamily [Intracellular trafficking secretion and vesicular transport].

22 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 161 174 14 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 140 160 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 175 194 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 95 113 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 134 139 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 292 302 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 33 72 40 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 260 291 32 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 66 284 219 PF03798 none TLC domain IPR006634
SMART 64 292 229 SM00724 none TRAM, LAG1 and CLN8 homology domains. IPR006634
Phobius 323 325 3 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 12 32 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 303 322 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 73 94 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 215 240 26 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 15 160 146 PTHR12560 "Reactome:REACT_22258";signature_desc=LONGEVITY ASSURANCE FACTOR 1 (LAG1) none IPR016439
PANTHER 183 303 121 PTHR12560 "Reactome:REACT_22258";signature_desc=LONGEVITY ASSURANCE FACTOR 1 (LAG1) none IPR016439
Phobius 195 214 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 241 259 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 114 133 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
ProSiteProfiles 64 292 229 PS50922 none TLC domain profile. IPR006634
Phobius 1 11 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none

3 Localization

Analysis Start End Length
TMHMM 15 32 17
TMHMM 219 241 22
TMHMM 261 283 22

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2002_QTL16_peak_Bud_burst_A4 Qrob_Chr11 11 s_A9OIA_166 s_1C6WBF_114 21,23 2,83 42,83 lod 5,1 7,2
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Champenoux_2015_nSecLBD_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 25,78 25,47 27,72 lod 6.3 16.6

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 28   Secretory pathway 3 0.764 0.051 NON-PLANT 28