Protein : Qrob_P0141470.2 Q. robur
Protein Identifier  ? Qrob_P0141470.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=1) PTHR11702:SF4 - NUCLEOLAR GTP-BINDING PROTEIN 1 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 452  
Kegg Orthology  K06943
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005525 GTP binding Interacting selectively and non-covalently with GTP, guanosine triphosphate.
GO:0015093 ferrous iron transmembrane transporter activity Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
GO:0015684 ferrous iron transport The directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

34 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103331450 1 442 + 442 Gaps:8 98.64 440 78.80 0.0 nucleolar GTP-binding protein 1
blastp_kegg lcl|pxb:103929741 1 450 + 450 Gaps:8 99.55 444 76.47 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pxb:103932039 1 450 + 450 Gaps:8 99.55 444 76.24 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|vvi:100263244 1 447 + 447 Gaps:7 98.88 445 76.14 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pper:PRUPE_ppa005854mg 1 442 + 442 Gaps:8 98.64 440 78.11 0.0 hypothetical protein
blastp_kegg lcl|pxb:103965497 1 450 + 450 Gaps:29 99.57 465 73.22 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|pop:POPTR_0002s13590g 1 447 + 447 Gaps:8 98.88 446 75.06 0.0 POPTRDRAFT_1072086 hypothetical protein
blastp_kegg lcl|rcu:RCOM_0658890 1 447 + 447 Gaps:9 99.77 443 75.79 0.0 nucleolar GTP-binding protein putative
blastp_kegg lcl|sot:102606333 1 450 + 450 Gaps:9 99.55 443 73.47 0.0 nucleolar GTP-binding protein 1-like
blastp_kegg lcl|tcc:TCM_011917 1 442 + 442 Gaps:11 98.18 439 75.64 0.0 P-loop containing nucleoside triphosphate hydrolases superfamily protein isoform 1
blastp_pdb 2e87_A 85 446 + 362 Gaps:21 96.64 357 27.83 2e-34 mol:protein length:357 Hypothetical protein PH1320
blastp_pdb 2qu8_A 236 378 + 143 Gaps:10 60.96 228 35.25 6e-23 mol:protein length:228 Putative nucleolar GTP-binding protein 1
blastp_uniprot_sprot sp|Q8SVJ8|NOG1_ENCCU 83 379 + 297 Gaps:28 54.36 528 34.49 3e-34 Nucleolar GTP-binding protein 1 OS Encephalitozoon cuniculi (strain GB-M1) GN NOG1 PE 3 SV 1
blastp_uniprot_sprot sp|Q9BZE4|NOG1_HUMAN 85 451 + 367 Gaps:24 55.68 634 28.61 3e-32 Nucleolar GTP-binding protein 1 OS Homo sapiens GN GTPBP4 PE 1 SV 3
blastp_uniprot_sprot sp|Q99ME9|NOG1_MOUSE 85 451 + 367 Gaps:24 55.68 634 28.61 3e-32 Nucleolar GTP-binding protein 1 OS Mus musculus GN Gtpbp4 PE 2 SV 3
blastp_uniprot_sprot sp|Q99P77|NOG1_RAT 85 451 + 367 Gaps:24 55.42 637 28.61 4e-32 Nucleolar GTP-binding protein 1 OS Rattus norvegicus GN Gtpbp4 PE 2 SV 3
blastp_uniprot_sprot sp|Q9V411|NOG1_DROME 85 433 + 349 Gaps:28 51.69 652 30.86 6e-32 Probable nucleolar GTP-binding protein 1 OS Drosophila melanogaster GN CG8801 PE 2 SV 1
blastp_uniprot_sprot sp|O44411|NOG1_CAEEL 85 451 + 367 Gaps:36 52.42 681 28.01 1e-30 Probable nucleolar GTP-binding protein 1 OS Caenorhabditis elegans GN T07A9.9 PE 3 SV 1
blastp_uniprot_sprot sp|Q9U6A9|NOG1_TRYBB 79 439 + 361 Gaps:32 53.28 655 30.66 8e-30 Nucleolar GTP-binding protein 1 OS Trypanosoma brucei brucei GN NOG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q6FRV0|NOG1_CANGA 84 380 + 297 Gaps:22 45.12 645 29.21 3e-29 Nucleolar GTP-binding protein 1 OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) GN NOG1 PE 3 SV 1
blastp_uniprot_sprot sp|Q02892|NOG1_YEAST 84 380 + 297 Gaps:22 44.98 647 28.18 1e-28 Nucleolar GTP-binding protein 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN NOG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9C6I8|NOG1_ARATH 140 444 + 305 Gaps:22 45.16 671 29.04 1e-28 Nucleolar GTP-binding protein 1 OS Arabidopsis thaliana GN At1g50920 PE 2 SV 1
rpsblast_cdd gnl|CDD|206684 247 431 + 185 Gaps:19 99.40 167 40.96 5e-50 cd01897 NOG Nucleolar GTP-binding protein (NOG). NOG1 is a nucleolar GTP-binding protein present in eukaryotes ranging from trypanosomes to humans. NOG1 is functionally linked to ribosome biogenesis and found in association with the nuclear pore complexes and identified in many preribosomal complexes. Thus defects in NOG1 can lead to defects in 60S biogenesis. The S. cerevisiae NOG1 gene is essential for cell viability and mutations in the predicted G motifs abrogate function. It is a member of the ODN family of GTP-binding proteins that also includes the bacterial Obg and DRG proteins.
rpsblast_cdd gnl|CDD|31281 82 378 + 297 Gaps:10 84.10 346 31.96 9e-49 COG1084 COG1084 Predicted GTPase [General function prediction only].
rpsblast_cdd gnl|CDD|206668 251 431 + 181 Gaps:25 99.40 167 31.93 1e-19 cd01881 Obg_like Obg-like family of GTPases consist of five subfamilies: Obg DRG YyaF/YchF Ygr210 and NOG1. The Obg-like subfamily consists of five well-delimited ancient subfamilies namely Obg DRG YyaF/YchF Ygr210 and NOG1. Four of these groups (Obg DRG YyaF/YchF and Ygr210) are characterized by a distinct glycine-rich motif immediately following the Walker B motif (G3 box). Obg/CgtA is an essential gene that is involved in the initiation of sporulation and DNA replication in the bacteria Caulobacter and Bacillus but its exact molecular role is unknown. Furthermore several OBG family members possess a C-terminal RNA-binding domain the TGS domain which is also present in threonyl-tRNA synthetase and in bacterial guanosine polyphosphatase SpoT. Nog1 is a nucleolar protein that might function in ribosome assembly. The DRG and Nog1 subfamilies are ubiquitous in archaea and eukaryotes the Ygr210 subfamily is present in archaea and fungi and the Obg and YyaF/YchF subfamilies are ubiquitous in bacteria and eukaryotes. The Obg/Nog1 and DRG subfamilies appear to form one major branch of the Obg family and the Ygr210 and YchF subfamilies form another branch. No GEFs GAPs or GDIs for Obg have been identified.
rpsblast_cdd gnl|CDD|115510 320 377 + 58 none 100.00 58 39.66 3e-15 pfam06858 NOG1 Nucleolar GTP-binding protein 1 (NOG1). This family represents a conserved region of approximately 60 residues in length within nucleolar GTP-binding protein 1 (NOG1). In S. cerevisiae the NOG1 gene has been shown to be essential for cell viability suggesting that NOG1 may play an important role in nucleolar functions. Family members include eukaryotic bacterial and archaeal proteins.
rpsblast_cdd gnl|CDD|30882 242 446 + 205 Gaps:29 53.12 369 29.08 1e-13 COG0536 Obg Predicted GTPase [General function prediction only].
rpsblast_cdd gnl|CDD|202050 248 375 + 128 Gaps:15 100.00 117 34.19 4e-12 pfam01926 MMR_HSR1 50S ribosome-binding GTPase. The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides with a preference for guanine nucleotide.
rpsblast_cdd gnl|CDD|183416 251 441 + 191 Gaps:40 45.90 390 30.73 1e-10 PRK12298 obgE GTPase CgtA Reviewed.
rpsblast_cdd gnl|CDD|206685 251 431 + 181 Gaps:39 97.65 170 33.73 6e-10 cd01898 Obg Obg GTPase. The Obg nucleotide binding protein subfamily has been implicated in stress response chromosome partitioning replication initiation mycelium development and sporulation. Obg proteins are among a large group of GTP binding proteins conserved from bacteria to humans. The E. coli homolog ObgE is believed to function in ribosomal biogenesis. Members of the subfamily contain two equally and highly conserved domains a C-terminal GTP binding domain and an N-terminal glycine-rich domain.

8 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 320 377 58 PF06858 none Nucleolar GTP-binding protein 1 (NOG1) IPR010674
Pfam 248 312 65 PF02421 none Ferrous iron transport protein B IPR011619
Gene3D 246 446 201 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 247 438 192 SSF52540 none none IPR027417
PANTHER 78 438 361 PTHR11702 none none none
PANTHER 78 438 361 PTHR11702:SF4 none none none
PRINTS 304 319 16 PR00326 none GTP1/OBG GTP-binding protein family signature IPR006073
PRINTS 249 269 21 PR00326 none GTP1/OBG GTP-binding protein family signature IPR006073

0 Localization

0 Qtllist

0 Targeting