GO:0003677
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DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0003676
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nucleic acid binding
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Interacting selectively and non-covalently with any nucleic acid. |
GO:0000166
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nucleotide binding
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Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
GO:0006260
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DNA replication
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The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
GO:0003887
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DNA-directed DNA polymerase activity
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Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. |
GO:0008408
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3'-5' exonuclease activity
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Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end. |