Protein : Qrob_P0137450.2 Q. robur
Protein Identifier  ? Qrob_P0137450.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PTHR13202 - MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT Gene Prediction Quality  validated
Protein length 

Sequence

Length: 95  
Kegg Orthology  K12946
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0008233 peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0005787 signal peptidase complex A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
GO:0006465 signal peptide processing The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.

22 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|csv:101211317 2 94 + 93 none 100.00 93 79.57 8e-50 probable signal peptidase complex subunit 1-like
blastp_kegg lcl|cmo:103488895 2 94 + 93 none 100.00 93 80.65 8e-50 probable signal peptidase complex subunit 1
blastp_kegg lcl|fve:101306007 2 93 + 92 none 97.87 94 81.52 3e-49 probable signal peptidase complex subunit 1-like
blastp_kegg lcl|cit:102628157 2 80 + 79 none 85.87 92 91.14 5e-47 probable signal peptidase complex subunit 1-like
blastp_kegg lcl|mtr:MTR_3g085510 2 94 + 93 none 100.00 93 78.49 5e-47 hypothetical protein
blastp_kegg lcl|gmx:100777545 2 94 + 93 none 100.00 93 76.34 2e-46 probable signal peptidase complex subunit 1-like
blastp_kegg lcl|pvu:PHAVU_002G174400g 2 94 + 93 none 100.00 93 76.34 1e-45 hypothetical protein
blastp_kegg lcl|gmx:100526911 2 94 + 93 none 100.00 93 75.27 2e-45 uncharacterized LOC100526911
blastp_kegg lcl|pmum:103322051 2 85 + 84 none 90.32 93 85.71 3e-45 probable signal peptidase complex subunit 1
blastp_kegg lcl|pxb:103961474 2 85 + 84 none 90.32 93 84.52 4e-45 probable signal peptidase complex subunit 1
blastp_uniprot_sprot sp|Q944J0|SPCS1_ARATH 2 94 + 93 Gaps:1 100.00 92 71.74 2e-38 Probable signal peptidase complex subunit 1 OS Arabidopsis thaliana GN At2g22425 PE 2 SV 1
blastp_uniprot_sprot sp|Q3T134|SPCS1_BOVIN 2 77 + 76 Gaps:3 77.45 102 44.30 1e-15 Signal peptidase complex subunit 1 OS Bos taurus GN SPCS1 PE 3 SV 1
blastp_uniprot_sprot sp|B0FWK4|SPCS1_PIG 2 77 + 76 Gaps:3 77.45 102 44.30 2e-15 Signal peptidase complex subunit 1 OS Sus scrofa GN SPCS1 PE 3 SV 1
blastp_uniprot_sprot sp|Q5RF96|SPCS1_PONAB 2 77 + 76 Gaps:3 77.45 102 44.30 2e-15 Signal peptidase complex subunit 1 OS Pongo abelii GN SPCS1 PE 3 SV 1
blastp_uniprot_sprot sp|Q9Y6A9|SPCS1_HUMAN 2 77 + 76 Gaps:3 77.45 102 44.30 2e-15 Signal peptidase complex subunit 1 OS Homo sapiens GN SPCS1 PE 1 SV 4
blastp_uniprot_sprot sp|Q9D958|SPCS1_MOUSE 2 68 + 67 none 41.61 161 47.76 9e-15 Signal peptidase complex subunit 1 OS Mus musculus GN Spcs1 PE 2 SV 3
blastp_uniprot_sprot sp|Q54Y83|SPCS1_DICDI 2 72 + 71 none 88.75 80 33.80 1e-10 Signal peptidase complex subunit 1 OS Dictyostelium discoideum GN spcs1 PE 3 SV 1
blastp_uniprot_sprot sp|Q9VAL0|SPCS1_DROME 2 70 + 69 none 70.41 98 34.78 3e-09 Signal peptidase complex subunit 1 OS Drosophila melanogaster GN Spase12 PE 1 SV 2
blastp_uniprot_sprot sp|Q61CQ8|SPCS1_CAEBR 2 70 + 69 Gaps:1 61.95 113 35.71 8e-09 Probable signal peptidase complex subunit 1 OS Caenorhabditis briggsae GN CBG12804 PE 3 SV 1
blastp_uniprot_sprot sp|O44953|SPCS1_CAEEL 2 71 + 70 Gaps:1 67.62 105 32.39 2e-07 Probable signal peptidase complex subunit 1 OS Caenorhabditis elegans GN C34B2.10 PE 3 SV 1
rpsblast_cdd gnl|CDD|191571 2 75 + 74 none 97.37 76 47.30 1e-23 pfam06645 SPC12 Microsomal signal peptidase 12 kDa subunit (SPC12). This family consists of several microsomal signal peptidase 12 kDa subunit proteins. Translocation of polypeptide chains across the endoplasmic reticulum (ER) membrane is triggered by signal sequences. Subsequently signal recognition particle interacts with its membrane receptor and the ribosome-bound nascent chain is targeted to the ER where it is transferred into a protein-conducting channel. At some point a second signal sequence recognition event takes place in the membrane and translocation of the nascent chain through the membrane occurs. The signal sequence of most secretory and membrane proteins is cleaved off at this stage. Cleavage occurs by the signal peptidase complex (SPC) as soon as the lumenal domain of the translocating polypeptide is large enough to expose its cleavage site to the enzyme. The signal peptidase complex is possibly also involved in proteolytic events in the ER membrane other than the processing of the signal sequence for example the further digestion of the cleaved signal peptide or the degradation of membrane proteins. Mammalian signal peptidase is as a complex of five different polypeptide chains. This family represents the 12 kDa subunit (SPC12).
rpsblast_kog gnl|CDD|39315 2 94 + 93 Gaps:9 83.17 101 36.90 6e-14 KOG4112 KOG4112 KOG4112 Signal peptidase subunit [Intracellular trafficking secretion and vesicular transport].

8 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 94 94 PTHR13202:SF0 none none none
Pfam 2 74 73 PF06645 none Microsomal signal peptidase 12 kDa subunit (SPC12) IPR009542
PANTHER 1 94 94 PTHR13202 none none IPR009542
Phobius 39 60 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 61 94 34 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 11 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 33 38 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 12 32 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

2 Localization

Analysis Start End Length
TMHMM 13 35 22
TMHMM 39 61 22

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
PM_1999_QTL14_peak_Bud_burst_3P Qrob_Chr03 3 s_2F0SI1_756 v_6056_735 11,78 3,78 50,78 lod 2,5 4,5

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 29   Secretory pathway 1 0.992 0.018 NON-PLANT 29