Protein : Qrob_P0083090.2 Q. robur
Protein Identifier  ? Qrob_P0083090.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K16812 - targeting protein for Xklp2 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 794  
Kegg Orthology  K16812
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0007067 mitotic nuclear division A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
GO:0005874 microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
GO:0005819 spindle The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

16 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_008153 17 786 + 770 Gaps:47 97.49 758 74.56 0.0 Targeting protein for XKLP2 putative isoform 1
blastp_kegg lcl|mdm:103444442 5 786 + 782 Gaps:66 98.10 791 71.01 0.0 protein TPX2
blastp_kegg lcl|cic:CICLE_v10014346mg 14 789 + 776 Gaps:40 97.81 777 71.58 0.0 hypothetical protein
blastp_kegg lcl|cit:102608685 14 789 + 776 Gaps:40 97.81 777 71.58 0.0 protein TPX2-like
blastp_kegg lcl|pmum:103328467 20 786 + 767 Gaps:78 95.04 746 74.05 0.0 protein TPX2
blastp_kegg lcl|csv:101211649 20 784 + 765 Gaps:47 96.09 768 71.68 0.0 uncharacterized LOC101211649
blastp_kegg lcl|cmo:103495480 20 785 + 766 Gaps:44 96.12 774 70.97 0.0 protein TPX2
blastp_kegg lcl|vvi:100262517 18 786 + 769 Gaps:75 97.64 805 69.47 0.0 uncharacterized LOC100262517
blastp_kegg lcl|fve:101292238 10 793 + 784 Gaps:92 99.88 825 66.26 0.0 protein TPX2-like
blastp_kegg lcl|pop:POPTR_0007s01050g 15 786 + 772 Gaps:70 94.04 755 73.10 0.0 POPTRDRAFT_763736 hypothetical protein
blastp_uniprot_sprot sp|F4I2H7|TPX2_ARATH 12 786 + 775 Gaps:42 92.78 790 64.12 0.0 Protein TPX2 OS Arabidopsis thaliana GN TPX2 PE 1 SV 1
blastp_uniprot_sprot sp|E2RYF8|TPX2_PATPE 326 754 + 429 Gaps:108 45.01 891 29.68 7e-13 Targeting protein for Xklp2 homolog OS Patiria pectinifera GN TPX2 PE 2 SV 1
blastp_uniprot_sprot sp|A2APB8|TPX2_MOUSE 365 754 + 390 Gaps:96 47.52 745 31.92 2e-08 Targeting protein for Xklp2 OS Mus musculus GN Tpx2 PE 1 SV 1
blastp_uniprot_sprot sp|Q6DDV8|TPX2B_XENLA 460 775 + 316 Gaps:76 41.12 715 31.97 6e-06 Targeting protein for Xklp2-B OS Xenopus laevis GN tpx2-b PE 2 SV 1
rpsblast_cdd gnl|CDD|192955 358 539 + 182 Gaps:2 100.00 176 53.98 3e-41 pfam12214 TPX2_importin Cell cycle regulated microtubule associated protein. This domain is found in eukaryotes. This domain is typically between 127 to 182 amino acids in length. This domain is found associated with pfam06886. This domain is found in the protein TPX2 (a.k.a p100) which is involved in cell cycling. It is only expressed between the start of the S phase and completion of cytokinesis. The microtubule-associated protein TPX2 has been reported to be crucial for mitotic spindle formation. This domain is close to the C terminal of TPX2. The protein importin alpha regulates the activity of TPX2 by binding to the nuclear localisation signal in this domain.
rpsblast_cdd gnl|CDD|191634 695 751 + 57 none 100.00 57 50.88 7e-12 pfam06886 TPX2 Targeting protein for Xklp2 (TPX2). This family represents a conserved region approximately 60 residues long within the eukaryotic targeting protein for Xklp2 (TPX2). Xklp2 is a kinesin-like protein localised on centrosomes throughout the cell cycle and on spindle pole microtubules during metaphase. In Xenopus it has been shown that Xklp2 protein is required for centrosome separation and maintenance of spindle bi-polarity. TPX2 is a microtubule-associated protein that mediates the binding of the C-terminal domain of Xklp2 to microtubules. It is phosphorylated during mitosis in a microtubule-dependent way.

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Coils 636 670 35 Coil none none none
Pfam 359 533 175 PF12214 none Cell cycle regulated microtubule associated protein IPR027330
PANTHER 13 789 777 PTHR14326:SF9 none none none
Pfam 695 751 57 PF06886 none Targeting protein for Xklp2 (TPX2) IPR027329
PANTHER 13 789 777 PTHR14326 none none IPR009675
Coils 704 725 22 Coil none none none

0 Localization

16 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran_2000_2002_QTL3_Delta.F Qrob_Chr08 8 s_1A3EF7_1406 s_1AIWYC_607 30.17 21,01 40,21 lod 6.8553 0.055
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Bourran2_2014_nPriLBD_A4 Qrob_Chr08 8 PIE175 v_9164_159 31,85 15,39 48,29 lod 2,8308 6,8
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL3_d13Cf Qrob_Chr08 8 v_5216_549 v_11625_20 37.08 12,26 54,9 lod 6.5888 0.04
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting