Protein : Qrob_P0068280.2 Q. robur
Protein Identifier  ? Qrob_P0068280.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K13783 - MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 497  
Kegg Orthology  K13783
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.

37 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pop:POPTR_0018s12290g 1 496 + 496 Gaps:12 100.00 506 76.88 0.0 POPTRDRAFT_911228 glycerol-3-phosphate transporter family protein
blastp_kegg lcl|cic:CICLE_v10008087mg 1 496 + 496 Gaps:8 99.80 497 79.23 0.0 hypothetical protein
blastp_kegg lcl|pper:PRUPE_ppa004556mg 1 496 + 496 Gaps:9 100.00 503 78.33 0.0 hypothetical protein
blastp_kegg lcl|cit:102615792 1 496 + 496 Gaps:8 99.80 497 79.23 0.0 putative glycerol-3-phosphate transporter 5-like
blastp_kegg lcl|pmum:103341202 1 496 + 496 Gaps:9 100.00 503 78.53 0.0 putative glycerol-3-phosphate transporter 5
blastp_kegg lcl|pxb:103949143 1 487 + 487 Gaps:9 98.80 500 79.55 0.0 putative glycerol-3-phosphate transporter 5
blastp_kegg lcl|pxb:103930764 1 487 + 487 Gaps:7 98.80 498 79.47 0.0 putative glycerol-3-phosphate transporter 5
blastp_kegg lcl|vvi:100248238 1 487 + 487 Gaps:7 100.00 490 79.80 0.0 putative glycerol-3-phosphate transporter 5-like
blastp_kegg lcl|gmx:100813689 1 484 + 484 Gaps:8 99.59 492 78.78 0.0 putative glycerol-3-phosphate transporter 5-like
blastp_kegg lcl|tcc:TCM_038248 1 496 + 496 Gaps:7 100.00 497 79.28 0.0 Major facilitator superfamily protein isoform 1
blastp_pdb 1pw4_A 9 480 + 472 Gaps:59 96.01 451 25.87 7e-17 mol:protein length:451 Glycerol-3-phosphate transporter
blastp_uniprot_sprot sp|Q9SL56|GLPT5_ARATH 1 480 + 480 Gaps:4 97.36 493 74.79 0.0 Putative glycerol-3-phosphate transporter 5 OS Arabidopsis thaliana GN At2g13100 PE 2 SV 2
blastp_uniprot_sprot sp|Q9C5L3|GLPT1_ARATH 2 487 + 486 Gaps:25 95.03 523 56.54 0.0 Putative glycerol-3-phosphate transporter 1 OS Arabidopsis thaliana GN At3g47420 PE 2 SV 1
blastp_uniprot_sprot sp|Q9SA71|GLPT3_ARATH 14 480 + 467 Gaps:17 92.94 510 54.43 1e-177 Putative glycerol-3-phosphate transporter 3 OS Arabidopsis thaliana GN At1g30560 PE 3 SV 1
blastp_uniprot_sprot sp|Q9SB41|GLPT2_ARATH 28 483 + 456 Gaps:12 88.10 504 56.31 3e-171 Putative glycerol-3-phosphate transporter 2 OS Arabidopsis thaliana GN At4g25220 PE 2 SV 1
blastp_uniprot_sprot sp|O23596|GLPT4_ARATH 2 483 + 482 Gaps:45 95.77 544 51.25 8e-170 Putative glycerol-3-phosphate transporter 4 OS Arabidopsis thaliana GN At4g17550 PE 3 SV 2
blastp_uniprot_sprot sp|Q7SY29|SPX2_DANRE 7 481 + 475 Gaps:23 96.76 494 47.70 4e-140 Sugar phosphate exchanger 2 OS Danio rerio GN slc37a2 PE 2 SV 1
blastp_uniprot_sprot sp|Q58CV5|SPX2_BOVIN 26 487 + 462 Gaps:28 97.35 491 48.54 4e-135 Sugar phosphate exchanger 2 OS Bos taurus GN SLC37A2 PE 2 SV 1
blastp_uniprot_sprot sp|Q9WU81|SPX2_MOUSE 32 479 + 448 Gaps:21 92.02 501 48.81 1e-133 Sugar phosphate exchanger 2 OS Mus musculus GN Slc37a2 PE 1 SV 1
blastp_uniprot_sprot sp|Q8TED4|SPX2_HUMAN 31 479 + 449 Gaps:29 92.22 501 49.35 5e-132 Sugar phosphate exchanger 2 OS Homo sapiens GN SLC37A2 PE 2 SV 2
blastp_uniprot_sprot sp|Q8AVC3|SPX2_XENLA 7 480 + 474 Gaps:29 96.79 499 47.62 2e-130 Sugar phosphate exchanger 2 OS Xenopus laevis GN slc37a2 PE 2 SV 1
rpsblast_cdd gnl|CDD|32452 23 481 + 459 Gaps:55 93.75 448 28.81 1e-41 COG2271 UhpC Sugar phosphate permease [Carbohydrate transport and metabolism].
rpsblast_cdd gnl|CDD|162086 85 457 + 373 Gaps:39 91.82 379 29.89 1e-30 TIGR00881 2A0104 phosphoglycerate transporter family protein.
rpsblast_cdd gnl|CDD|129795 85 480 + 396 Gaps:28 85.84 438 25.27 6e-23 TIGR00712 glpT glycerol-3-phosphate transporter. This model describes a very hydrophobic protein predicted to span the membrane at least 8 times. The two members confirmed experimentally as glycerol-3-phosphate transporters from E. coli and B. subtilis share more than 50 % amino acid identity. Proteins of the hexose phosphate and phosphoglycerate transport systems are also quite similar.
rpsblast_cdd gnl|CDD|181950 82 480 + 399 Gaps:67 83.94 467 27.55 3e-20 PRK09556 uhpT sugar phosphate antiporter Reviewed.
rpsblast_cdd gnl|CDD|191813 91 442 + 352 Gaps:47 88.73 346 22.15 3e-17 pfam07690 MFS_1 Major Facilitator Superfamily.
rpsblast_cdd gnl|CDD|183266 92 472 + 381 Gaps:64 81.80 434 28.17 6e-17 PRK11663 PRK11663 regulatory protein UhpC Provisional.
rpsblast_cdd gnl|CDD|162094 91 448 + 358 Gaps:32 83.71 399 25.75 1e-16 TIGR00893 2A0114 D-galactonate transporter.
rpsblast_cdd gnl|CDD|183068 95 482 + 388 Gaps:44 81.42 452 25.54 8e-15 PRK11273 glpT sn-glycerol-3-phosphate transporter Provisional.
rpsblast_cdd gnl|CDD|119392 91 475 + 385 Gaps:78 88.35 352 27.01 9e-14 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..

32 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PIRSF 18 487 470 PIRSF002808 none none IPR000849
Phobius 44 113 70 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 171 181 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 476 496 21 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 202 206 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 382 410 29 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 268 482 215 SSF103473 none none IPR020846
SUPERFAMILY 22 239 218 SSF103473 none none IPR020846
Phobius 287 308 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 328 349 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 114 135 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 411 421 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 182 201 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 25 43 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 136 140 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 280 478 199 G3DSA:1.20.1250.20 none none none
Pfam 87 410 324 PF07690 none Major Facilitator Superfamily IPR011701
Phobius 309 327 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 30 234 205 G3DSA:1.20.1250.20 none none none
Phobius 207 229 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 377 381 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 230 286 57 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 28 479 452 PTHR11662:SF153 none none none
ProSiteProfiles 34 478 445 PS50850 none Major facilitator superfamily (MFS) profile. IPR020846
Phobius 456 475 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 422 444 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 356 376 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 445 455 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 28 479 452 PTHR11662 none none none
Phobius 350 355 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none

11 Localization

Analysis Start End Length
TMHMM 25 44 19
TMHMM 114 136 22
TMHMM 356 378 22
TMHMM 423 445 22
TMHMM 290 312 22
TMHMM 146 168 22
TMHMM 327 349 22
TMHMM 388 410 22
TMHMM 181 203 22
TMHMM 455 472 17
TMHMM 207 229 22

0 Qtllist

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 41   Secretory pathway 5 0.625 0.052 NON-PLANT 41