Protein : Qrob_P0052900.2 Q. robur
Protein Identifier  ? Qrob_P0052900.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) 2.7.1.130 - Tetraacyldisaccharide 4'-kinase. Code Enzyme  EC:2.7.1.130
Gene Prediction Quality  validated Protein length 

Sequence

Length: 399  
Kegg Orthology  K00912
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0009029 tetraacyldisaccharide 4'-kinase activity Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a).
GO:0009245 lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of six fatty acyl chains linked to two glucosamine residues.

25 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa006670mg 1 398 + 398 Gaps:2 99.50 400 71.11 0.0 hypothetical protein
blastp_kegg lcl|pmum:103326438 1 391 + 391 Gaps:2 98.74 396 70.59 0.0 probable tetraacyldisaccharide 4'-kinase mitochondrial
blastp_kegg lcl|cit:102624214 1 393 + 393 Gaps:1 100.00 392 69.39 0.0 probable tetraacyldisaccharide 4'-kinase mitochondrial-like
blastp_kegg lcl|mdm:103448393 1 389 + 389 Gaps:4 100.00 389 67.87 0.0 probable tetraacyldisaccharide 4'-kinase mitochondrial
blastp_kegg lcl|fve:101303894 1 391 + 391 Gaps:2 100.00 389 67.61 0.0 tetraacyldisaccharide 4'-kinase-like
blastp_kegg lcl|pop:POPTR_0001s44470g 1 398 + 398 Gaps:2 99.50 398 67.17 0.0 tetraacyldisaccharide 4'-kinase family protein
blastp_kegg lcl|vvi:100245200 1 393 + 393 Gaps:5 85.34 464 67.68 0.0 tetraacyldisaccharide 4'-kinase-like
blastp_kegg lcl|tcc:TCM_030849 1 378 + 378 Gaps:40 95.39 434 62.80 2e-180 Tetraacyldisaccharide 4'-kinase family protein putative isoform 1
blastp_kegg lcl|mtr:MTR_3g052590 1 398 + 398 Gaps:4 100.00 400 60.75 6e-176 Tetraacyldisaccharide 4'-kinase
blastp_kegg lcl|gmx:100789612 1 397 + 397 Gaps:1 99.00 400 62.12 2e-174 probable tetraacyldisaccharide 4'-kinase mitochondrial-like
blastp_uniprot_sprot sp|Q8LEA0|LPXK_ARATH 1 394 + 394 Gaps:3 98.99 395 58.06 1e-155 Probable tetraacyldisaccharide 4'-kinase mitochondrial OS Arabidopsis thaliana GN LPXK PE 2 SV 1
blastp_uniprot_sprot sp|Q2LVL1|LPXK_SYNAS 31 391 + 361 Gaps:40 92.78 374 35.16 1e-38 Tetraacyldisaccharide 4'-kinase OS Syntrophus aciditrophicus (strain SB) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|B8CZC3|LPXK_HALOH 12 350 + 339 Gaps:37 88.54 384 32.94 8e-36 Tetraacyldisaccharide 4'-kinase OS Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|Q6ALV8|LPXK_DESPS 36 346 + 311 Gaps:34 84.77 348 33.90 2e-30 Tetraacyldisaccharide 4'-kinase OS Desulfotalea psychrophila (strain LSv54 / DSM 12343) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|B2KC48|LPXK_ELUMP 36 320 + 285 Gaps:51 74.33 374 30.58 2e-29 Tetraacyldisaccharide 4'-kinase OS Elusimicrobium minutum (strain Pei191) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|B3QLP5|LPXK_CHLP8 31 349 + 319 Gaps:42 83.38 361 31.89 3e-29 Tetraacyldisaccharide 4'-kinase OS Chlorobaculum parvum (strain NCIB 8327) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|A0KLY1|LPXK_AERHH 38 346 + 309 Gaps:82 79.58 333 35.09 4e-29 Tetraacyldisaccharide 4'-kinase OS Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / NCIB 9240) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|Q8A6K1|LPXK_BACTN 35 349 + 315 Gaps:35 81.05 380 30.52 6e-29 Tetraacyldisaccharide 4'-kinase OS Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|A1AXA3|LPXK_RUTMC 36 320 + 285 Gaps:33 80.00 315 32.54 2e-28 Tetraacyldisaccharide 4'-kinase OS Ruthia magnifica subsp. Calyptogena magnifica GN lpxK PE 3 SV 1
blastp_uniprot_sprot sp|Q3J7R7|LPXK_NITOC 31 346 + 316 Gaps:81 80.18 338 35.06 2e-28 Tetraacyldisaccharide 4'-kinase OS Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN lpxK PE 3 SV 1
rpsblast_cdd gnl|CDD|145645 32 391 + 360 Gaps:80 98.74 318 39.81 2e-60 pfam02606 LpxK Tetraacyldisaccharide-1-P 4'-kinase. This family consists of tetraacyldisaccharide-1-P 4'-kinase also known as Lipid-A 4'-kinase or Lipid A biosynthesis protein LpxK EC:2.7.1.130. This enzyme catalyzes the reaction: ATP + 2 3-bis(3-hydroxytetradecanoyl)-D -glucosaminyl-(beta-D-1 6)-2 3-bis(3-hydroxytetradecanoyl)-D-glu cosam inyl beta-phosphate < > ADP + 2 3 2' 3'-tetrakis(3-hydroxytetradecanoyl)-D- glucosaminyl-1 6-beta-D-glucosamine 1 4'-bisphosphate. This enzyme is involved in the synthesis of lipid A portion of the bacterial lipopolysaccharide layer (LPS). The family contains a P-loop motif at the N terminus.
rpsblast_cdd gnl|CDD|179082 24 347 + 324 Gaps:83 85.67 328 38.08 1e-40 PRK00652 lpxK tetraacyldisaccharide 4'-kinase Reviewed.
rpsblast_cdd gnl|CDD|31849 27 347 + 321 Gaps:76 83.63 336 33.10 4e-37 COG1663 LpxK Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis outer membrane].
rpsblast_cdd gnl|CDD|161995 36 347 + 312 Gaps:48 87.46 311 32.72 2e-32 TIGR00682 lpxK tetraacyldisaccharide 4'-kinase. Also called lipid-A 4'-kinase. This essential gene encodes an enzyme in the pathway of lipid A biosynthesis in Gram-negative organisms. A single copy of this protein is found in Gram-negative bacteria. PSI-BLAST converges on this set of apparent orthologs without identifying any other homologs.
rpsblast_cdd gnl|CDD|179349 36 346 + 311 Gaps:79 79.88 338 30.74 3e-22 PRK01906 PRK01906 tetraacyldisaccharide 4'-kinase Provisional.

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 391 391 PTHR30160:SF0 none none none
Phobius 1 26 26 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 46 398 353 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Hamap 7 391 385 MF_00409 "KEGG:00540+2.7.1.130","UniPathway:UPA00359" Tetraacyldisaccharide 4'-kinase [lpxK]. IPR003758
PANTHER 1 391 391 PTHR30160 none none none
Pfam 31 383 353 PF02606 "KEGG:00540+2.7.1.130","UniPathway:UPA00359" Tetraacyldisaccharide-1-P 4'-kinase IPR003758
Phobius 27 45 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

1 Localization

Analysis Start End Length
TMHMM 21 43 22

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting