Protein : Qrob_P0009880.2 Q. robur
Protein Identifier  ? Qrob_P0009880.2 Organism . Name  Quercus robur
Score  28.0 Score Type  egn
Protein Description  (M=1) KOG0044//KOG1992//KOG4223 - Ca2+ sensor (EF-Hand superfamily) [Signal transduction mechanisms]. // Nuclear export receptor CSE1/CAS (importin beta superfamily) [Nuclear structure Intracellular trafficking secretion and vesicular transport]. // Reticulocalbin calumenin DNA supercoiling factor and related Ca2+-binding proteins of the CREC family (EF-Hand protein superfamily) [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 510  
Kegg Orthology  K18423
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0006886 intracellular protein transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
GO:0005509 calcium ion binding Interacting selectively and non-covalently with calcium ions (Ca2+).

29 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa000879mg 123 374 + 252 Gaps:26 27.57 972 63.43 5e-97 hypothetical protein
blastp_kegg lcl|pmum:103332192 123 374 + 252 Gaps:26 27.57 972 63.43 7e-97 exportin-2
blastp_kegg lcl|pop:POPTR_0014s09550g 158 374 + 217 Gaps:21 24.56 969 67.65 3e-96 POPTRDRAFT_664131 Importin-alpha re-exporter family protein
blastp_kegg lcl|rcu:RCOM_0716980 158 374 + 217 Gaps:21 24.56 969 66.39 6e-96 importin-alpha re-exporter putative
blastp_kegg lcl|brp:103866460 158 374 + 217 Gaps:21 24.51 971 65.97 7e-96 exportin-2
blastp_kegg lcl|eus:EUTSA_v10001293mg 158 374 + 217 Gaps:21 24.49 972 65.13 8e-96 hypothetical protein
blastp_kegg lcl|cic:CICLE_v10018709mg 121 374 + 254 Gaps:26 27.69 975 63.33 2e-95 hypothetical protein
blastp_kegg lcl|mdm:103417637 158 374 + 217 Gaps:21 24.51 971 66.81 4e-95 exportin-2-like
blastp_kegg lcl|pop:POPTR_0002s17340g 158 374 + 217 Gaps:21 24.56 969 68.07 5e-95 POPTRDRAFT_644596 Importin-alpha re-exporter family protein
blastp_kegg lcl|cit:102626753 121 374 + 254 Gaps:26 27.69 975 62.96 9e-95 exportin-2-like
blastp_pdb 1wa5_C 158 373 + 216 Gaps:30 25.62 960 30.08 3e-25 mol:protein length:960 IMPORTIN ALPHA RE-EXPORTER
blastp_pdb 1z3h_B 158 373 + 216 Gaps:30 25.41 968 30.08 3e-25 mol:protein length:968 Importin alpha re-exporter
blastp_pdb 1z3h_A 158 373 + 216 Gaps:30 25.41 968 30.08 3e-25 mol:protein length:968 Importin alpha re-exporter
blastp_uniprot_sprot sp|Q9ZPY7|XPO2_ARATH 125 374 + 250 Gaps:27 27.47 972 60.67 5e-93 Exportin-2 OS Arabidopsis thaliana GN CAS PE 2 SV 1
blastp_uniprot_sprot sp|Q9ERK4|XPO2_MOUSE 162 373 + 212 Gaps:24 24.30 971 37.29 7e-40 Exportin-2 OS Mus musculus GN Cse1l PE 2 SV 1
blastp_uniprot_sprot sp|Q5R9J2|XPO2_PONAB 162 373 + 212 Gaps:24 24.30 971 37.29 2e-39 Exportin-2 OS Pongo abelii GN CSE1L PE 2 SV 1
blastp_uniprot_sprot sp|A5D785|XPO2_BOVIN 162 373 + 212 Gaps:24 24.30 971 37.29 2e-39 Exportin-2 OS Bos taurus GN CSE1L PE 2 SV 1
blastp_uniprot_sprot sp|P55060|XPO2_HUMAN 162 373 + 212 Gaps:24 24.30 971 37.29 3e-39 Exportin-2 OS Homo sapiens GN CSE1L PE 1 SV 3
blastp_uniprot_sprot sp|Q8AY73|XPO2_ORENI 163 373 + 211 Gaps:24 24.20 971 37.02 3e-39 Exportin-2 OS Oreochromis niloticus GN cse1l PE 2 SV 1
blastp_uniprot_sprot sp|Q9XZU1|XPO2_DROME 163 400 + 238 Gaps:35 28.00 975 34.43 3e-38 Exportin-2 OS Drosophila melanogaster GN Cas PE 2 SV 2
blastp_uniprot_sprot sp|Q9PTU3|XPO2_PAGMA 163 373 + 211 Gaps:24 24.20 971 35.74 8e-38 Exportin-2 OS Pagrus major GN cse1l PE 2 SV 1
blastp_uniprot_sprot sp|Q6GMY9|XPO2_XENLA 162 367 + 206 Gaps:24 23.69 971 36.52 6e-37 Exportin-2 OS Xenopus laevis GN cse1l PE 2 SV 1
blastp_uniprot_sprot sp|Q7SZC2|XPO2_DANRE 162 367 + 206 Gaps:24 23.69 971 36.52 1e-35 Exportin-2 OS Danio rerio GN cse1l PE 2 SV 1
rpsblast_cdd gnl|CDD|117083 161 315 + 155 Gaps:23 48.11 370 44.38 3e-50 pfam08506 Cse1 Cse1. This domain is present in Cse1 nuclear export receptor proteins. Cse1 mediates the nuclear export of importin alpha. This domain contains HEAT repeats.
rpsblast_cdd gnl|CDD|190619 316 371 + 56 none 12.87 435 51.79 4e-18 pfam03378 CAS_CSE1 CAS/CSE protein C-terminus. Mammalian cellular apoptosis susceptibility (CAS) proteins are homologous to the yeast chromosome-segregation protein CSE1. This family aligns the C-terminal halves (approximately). CAS is involved in both cellular apoptosis and proliferation. Apoptosis is inhibited in CAS-depleted cells while the expression of CAS correlates to the degree of cellular proliferation. Like CSE1 it is essential for the mitotic checkpoint in the cell cycle (CAS depletion blocks the cell in the G2 phase) and has been shown to be associated with the microtubule network and the mitotic spindle as is the protein MEK which is thought to regulate the intracellular localisation (predominantly nuclear vs. predominantly cytosolic) of CAS. In the nucleus CAS acts as a nuclear transport factor in the importin pathway. The importin pathway mediates the nuclear transport of several proteins that are necessary for mitosis and further progression. CAS is therefore thought to affect the cell cycle through its effect on the nuclear transport of these proteins. Since apoptosis also requires the nuclear import of several proteins (such as P53 and transcription factors) it has been suggested that CAS also enables apoptosis by facilitating the nuclear import of at least a subset of these essential proteins.
rpsblast_cdd gnl|CDD|35216 163 378 + 216 Gaps:30 24.08 947 18.42 2e-07 COG5657 CSE1 CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning].
rpsblast_kog gnl|CDD|37203 161 378 + 218 Gaps:30 25.21 960 41.74 3e-61 KOG1992 KOG1992 KOG1992 Nuclear export receptor CSE1/CAS (importin beta superfamily) [Nuclear structure Intracellular trafficking secretion and vesicular transport].
rpsblast_kog gnl|CDD|39424 347 508 + 162 Gaps:21 43.38 325 34.75 9e-28 KOG4223 KOG4223 KOG4223 Reticulocalbin calumenin DNA supercoiling factor and related Ca2+-binding proteins of the CREC family (EF-Hand protein superfamily) [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport].
rpsblast_kog gnl|CDD|35267 341 482 + 142 Gaps:38 64.25 193 33.06 2e-09 KOG0044 KOG0044 KOG0044 Ca2+ sensor (EF-Hand superfamily) [Signal transduction mechanisms].

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSiteProfiles 456 491 36 PS50222 none EF-hand calcium-binding domain profile. IPR002048
PANTHER 163 378 216 PTHR10997:SF8 none none none
Pfam 423 482 60 PF13499 none EF-hand domain pair IPR011992
Pfam 161 272 112 PF08506 none Cse1 IPR013713
Gene3D 365 483 119 G3DSA:1.10.238.10 none none IPR011992
PANTHER 163 378 216 PTHR10997 none none none
Gene3D 161 364 204 G3DSA:1.25.10.10 none none IPR011989
ProSitePatterns 430 442 13 PS00018 none EF-hand calcium-binding domain. IPR018247
ProSiteProfiles 380 402 23 PS50222 none EF-hand calcium-binding domain profile. IPR002048
ProSitePatterns 469 481 13 PS00018 none EF-hand calcium-binding domain. IPR018247
SUPERFAMILY 163 405 243 SSF48371 none none IPR016024
SUPERFAMILY 356 487 132 SSF47473 none none none
ProSitePatterns 380 392 13 PS00018 none EF-hand calcium-binding domain. IPR018247
ProSiteProfiles 417 452 36 PS50222 none EF-hand calcium-binding domain profile. IPR002048
Pfam 316 373 58 PF03378 none CAS/CSE protein, C-terminus IPR005043
Pfam 380 397 18 PF13833 none EF-hand domain pair none

0 Localization

12 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
Bourran2_2004_QTL9_peak_Bud_burst_3P Qrob_Chr02 2 s_1C34E9_788 v_12238_322 50 25 75 lod 4,4 10,1
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran_2000_2002_QTL2_Delta.F Qrob_Chr02 2 s_1CSO13_1244 s_1AVEUF_1540 55.44 46,71 63,68 lod 7.3232 0.058
Bourran2_2002_QTL7_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 29 52 lod 8,1 16
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL6_d13Cf Qrob_Chr02 2 s_1AEP21_172 v_6048_204 46.33 22,5 65,23 lod 4.972 0.03

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 12   Mitochondrion 4 0.022 0.749 NON-PLANT 12