Protein : Qrob_P0004360.2 Q. robur
Protein Identifier  ? Qrob_P0004360.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=4) K08150 - MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 579  
Kegg Orthology  K08150
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

38 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103325149 1 574 + 574 none 99.48 577 78.22 0.0 probable inositol transporter 2
blastp_kegg lcl|pper:PRUPE_ppa023920mg 1 574 + 574 none 99.48 577 78.05 0.0 hypothetical protein
blastp_kegg lcl|vvi:100246301 1 574 + 574 none 99.48 577 77.00 0.0 probable inositol transporter 2-like
blastp_kegg lcl|tcc:TCM_029440 1 577 + 577 Gaps:1 100.00 578 76.47 0.0 Inositol transporter 2 isoform 1
blastp_kegg lcl|cit:102620399 1 568 + 568 Gaps:3 98.62 579 78.46 0.0 probable inositol transporter 2-like
blastp_kegg lcl|mus:103983530 1 577 + 577 Gaps:1 99.65 578 76.04 0.0 probable inositol transporter 2
blastp_kegg lcl|cic:CICLE_v10014738mg 1 568 + 568 Gaps:3 98.62 579 78.11 0.0 hypothetical protein
blastp_kegg lcl|cmo:103487832 1 574 + 574 Gaps:1 98.79 580 75.74 0.0 probable inositol transporter 2
blastp_kegg lcl|csv:101213737 13 574 + 562 Gaps:1 95.57 587 77.18 0.0 probable inositol transporter 2-like
blastp_kegg lcl|atr:s00092p00111470 1 574 + 574 Gaps:4 100.00 576 75.52 0.0 AMTR_s00092p00111470 hypothetical protein
blastp_uniprot_sprot sp|Q9C757|INT2_ARATH 1 576 + 576 Gaps:2 99.66 580 73.01 0.0 Probable inositol transporter 2 OS Arabidopsis thaliana GN INT2 PE 1 SV 1
blastp_uniprot_sprot sp|O23492|INT4_ARATH 1 555 + 555 Gaps:11 96.22 582 59.29 0.0 Inositol transporter 4 OS Arabidopsis thaliana GN INT4 PE 1 SV 1
blastp_uniprot_sprot sp|Q9ZQP6|INT3_ARATH 24 555 + 532 Gaps:11 92.59 580 56.42 0.0 Probable inositol transporter 3 OS Arabidopsis thaliana GN INT3 PE 2 SV 1
blastp_uniprot_sprot sp|Q96QE2|MYCT_HUMAN 12 557 + 546 Gaps:28 84.26 648 40.11 1e-124 Proton myo-inositol cotransporter OS Homo sapiens GN SLC2A13 PE 1 SV 3
blastp_uniprot_sprot sp|Q8VZR6|INT1_ARATH 1 572 + 572 Gaps:11 97.05 509 57.29 2e-123 Inositol transporter 1 OS Arabidopsis thaliana GN INT1 PE 1 SV 1
blastp_uniprot_sprot sp|Q3UHK1|MYCT_MOUSE 12 557 + 546 Gaps:30 85.71 637 40.84 3e-117 Proton myo-inositol cotransporter OS Mus musculus GN Slc2a13 PE 2 SV 2
blastp_uniprot_sprot sp|Q921A2|MYCT_RAT 12 557 + 546 Gaps:30 85.71 637 40.84 4e-117 Proton myo-inositol cotransporter OS Rattus norvegicus GN Slc2a13 PE 2 SV 2
blastp_uniprot_sprot sp|Q0P4G6|GTR10_XENTR 19 562 + 544 Gaps:63 95.32 555 32.33 2e-71 Solute carrier family 2 facilitated glucose transporter member 10 OS Xenopus tropicalis GN slc2a10 PE 2 SV 1
blastp_uniprot_sprot sp|Q6GN01|GTR10_XENLA 30 559 + 530 Gaps:47 92.77 553 30.99 2e-69 Solute carrier family 2 facilitated glucose transporter member 10 OS Xenopus laevis GN slc2a10 PE 2 SV 1
blastp_uniprot_sprot sp|P46333|CSBC_BACSU 31 554 + 524 Gaps:13 93.06 461 41.96 2e-68 Probable metabolite transport protein CsbC OS Bacillus subtilis (strain 168) GN csbC PE 1 SV 3
rpsblast_cdd gnl|CDD|200987 29 554 + 526 Gaps:23 100.00 449 39.87 2e-75 pfam00083 Sugar_tr Sugar (and other) transporter.
rpsblast_cdd gnl|CDD|162084 22 550 + 529 Gaps:12 95.63 481 41.30 3e-73 TIGR00879 SP MFS transporter sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083).
rpsblast_cdd gnl|CDD|182225 22 553 + 532 Gaps:58 97.29 479 34.76 1e-57 PRK10077 xylE D-xylose transporter XylE Provisional.
rpsblast_cdd gnl|CDD|162095 23 360 + 338 Gaps:23 81.66 398 29.85 3e-26 TIGR00895 2A0115 benzoate transport.
rpsblast_cdd gnl|CDD|119392 25 207 + 183 Gaps:7 99.72 352 28.77 8e-22 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
rpsblast_cdd gnl|CDD|162097 78 356 + 279 Gaps:19 52.28 505 32.20 3e-20 TIGR00898 2A0119 cation transport protein.
rpsblast_cdd gnl|CDD|191813 35 366 + 332 Gaps:44 84.39 346 25.34 1e-16 pfam07690 MFS_1 Major Facilitator Superfamily.
rpsblast_cdd gnl|CDD|179668 28 230 + 203 Gaps:38 40.12 496 26.13 3e-12 PRK03893 PRK03893 putative sialic acid transporter Provisional.
rpsblast_cdd gnl|CDD|183424 31 216 + 186 Gaps:10 42.72 426 29.67 6e-12 PRK12307 PRK12307 putative sialic acid transporter Provisional.
rpsblast_cdd gnl|CDD|183191 73 227 + 155 Gaps:8 38.18 406 32.90 7e-12 PRK11551 PRK11551 putative 3-hydroxyphenylpropionic transporter MhpT Provisional.

45 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSitePatterns 128 153 26 PS00217 none Sugar transport proteins signature 2. IPR005829
Phobius 274 296 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 19 362 344 SSF103473 none none IPR020846
SUPERFAMILY 449 552 104 SSF103473 none none IPR020846
Phobius 335 340 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 444 578 135 PTHR24063 none none none
PANTHER 1 366 366 PTHR24063 none none none
TIGRFAM 21 370 350 TIGR00879 "Reactome:REACT_15518" SP: MFS transporter, sugar porter (SP) family IPR003663
Phobius 98 116 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 145 155 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 488 509 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PRINTS 37 47 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 123 142 20 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 455 476 22 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 478 490 13 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 284 294 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
Phobius 184 206 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 515 539 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 297 310 14 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 156 178 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 29 54 26 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 207 273 67 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 510 514 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 362 451 90 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 55 65 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 341 361 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 477 487 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 452 476 25 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 274 363 90 G3DSA:1.20.1250.20 none none none
Gene3D 449 551 103 G3DSA:1.20.1250.20 none none none

12 Localization

Analysis Start End Length
TMHMM 29 51 22
TMHMM 273 295 22
TMHMM 123 145 22
TMHMM 483 505 22
TMHMM 97 119 22
TMHMM 341 363 22
TMHMM 515 537 22
TMHMM 152 174 22
TMHMM 310 332 22
TMHMM 184 206 22
TMHMM 454 476 22
TMHMM 66 88 22

11 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran_2000_2002_QTL3_Delta.F Qrob_Chr08 8 s_1A3EF7_1406 s_1AIWYC_607 30.17 21,01 40,21 lod 6.8553 0.055
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nPriLBD_A4 Qrob_Chr08 8 PIE175 v_9164_159 31,85 15,39 48,29 lod 2,8308 6,8
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL3_d13Cf Qrob_Chr08 8 v_5216_549 v_11625_20 37.08 12,26 54,9 lod 6.5888 0.04

0 Targeting