Protein : Qrob_P0004330.2 Q. robur

Protein Identifier  ? Qrob_P0004330.2 Organism . Name  Quercus robur
Score  29.2 Score Type  egn
Protein Description  (M=4) K08150 - MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 506  
Kegg Orthology  K08150

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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

38 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100246301 15 501 + 487 none 84.40 577 75.56 0.0 probable inositol transporter 2-like
blastp_kegg lcl|pmum:103325149 15 501 + 487 none 84.40 577 74.95 0.0 probable inositol transporter 2
blastp_kegg lcl|tcc:TCM_029440 15 504 + 490 none 84.78 578 74.49 0.0 Inositol transporter 2 isoform 1
blastp_kegg lcl|pper:PRUPE_ppa023920mg 15 501 + 487 none 84.40 577 74.74 0.0 hypothetical protein
blastp_kegg lcl|cmo:103487832 15 501 + 487 Gaps:1 83.79 580 72.63 0.0 probable inositol transporter 2
blastp_kegg lcl|csv:101213737 15 501 + 487 Gaps:1 82.79 587 73.05 0.0 probable inositol transporter 2-like
blastp_kegg lcl|cit:102620399 15 495 + 481 none 83.07 579 74.01 0.0 probable inositol transporter 2-like
blastp_kegg lcl|cic:CICLE_v10014738mg 15 495 + 481 none 83.07 579 74.22 0.0 hypothetical protein
blastp_kegg lcl|mus:103983530 15 504 + 490 Gaps:1 84.60 578 71.78 0.0 probable inositol transporter 2
blastp_kegg lcl|atr:s00092p00111470 3 501 + 499 Gaps:12 88.37 576 68.96 0.0 AMTR_s00092p00111470 hypothetical protein
blastp_uniprot_sprot sp|Q9C757|INT2_ARATH 15 501 + 487 none 83.97 580 68.38 0.0 Probable inositol transporter 2 OS Arabidopsis thaliana GN INT2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9ZQP6|INT3_ARATH 1 482 + 482 Gaps:13 83.97 580 55.03 0.0 Probable inositol transporter 3 OS Arabidopsis thaliana GN INT3 PE 2 SV 1
blastp_uniprot_sprot sp|O23492|INT4_ARATH 15 482 + 468 Gaps:11 81.27 582 57.51 0.0 Inositol transporter 4 OS Arabidopsis thaliana GN INT4 PE 1 SV 1
blastp_uniprot_sprot sp|Q96QE2|MYCT_HUMAN 3 484 + 482 Gaps:25 74.85 648 40.41 3e-112 Proton myo-inositol cotransporter OS Homo sapiens GN SLC2A13 PE 1 SV 3
blastp_uniprot_sprot sp|Q3UHK1|MYCT_MOUSE 17 484 + 468 Gaps:27 73.94 637 40.13 2e-106 Proton myo-inositol cotransporter OS Mus musculus GN Slc2a13 PE 2 SV 2
blastp_uniprot_sprot sp|Q921A2|MYCT_RAT 17 484 + 468 Gaps:27 73.94 637 39.92 2e-106 Proton myo-inositol cotransporter OS Rattus norvegicus GN Slc2a13 PE 2 SV 2
blastp_uniprot_sprot sp|Q8VZR6|INT1_ARATH 1 503 + 503 Gaps:6 82.91 509 56.64 2e-97 Inositol transporter 1 OS Arabidopsis thaliana GN INT1 PE 1 SV 1
blastp_uniprot_sprot sp|Q0P4G6|GTR10_XENTR 3 489 + 487 Gaps:51 85.77 555 32.77 2e-63 Solute carrier family 2 facilitated glucose transporter member 10 OS Xenopus tropicalis GN slc2a10 PE 2 SV 1
blastp_uniprot_sprot sp|Q6GN01|GTR10_XENLA 3 484 + 482 Gaps:38 84.63 553 29.49 4e-58 Solute carrier family 2 facilitated glucose transporter member 10 OS Xenopus laevis GN slc2a10 PE 2 SV 1
blastp_uniprot_sprot sp|Q5J316|GTR12_BOVIN 3 484 + 482 Gaps:41 77.46 621 30.56 6e-58 Solute carrier family 2 facilitated glucose transporter member 12 OS Bos taurus GN SLC2A12 PE 1 SV 1
rpsblast_cdd gnl|CDD|200987 1 481 + 481 Gaps:15 88.20 449 39.90 4e-71 pfam00083 Sugar_tr Sugar (and other) transporter.
rpsblast_cdd gnl|CDD|162084 1 477 + 477 Gaps:9 83.78 481 40.45 5e-65 TIGR00879 SP MFS transporter sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083).
rpsblast_cdd gnl|CDD|182225 2 485 + 484 Gaps:36 85.59 479 35.12 5e-50 PRK10077 xylE D-xylose transporter XylE Provisional.
rpsblast_cdd gnl|CDD|162095 2 282 + 281 Gaps:22 68.09 398 29.52 3e-21 TIGR00895 2A0115 benzoate transport.
rpsblast_cdd gnl|CDD|162097 5 284 + 280 Gaps:19 52.87 505 28.46 5e-21 TIGR00898 2A0119 cation transport protein.
rpsblast_cdd gnl|CDD|119392 1 134 + 134 Gaps:3 75.00 352 30.68 1e-19 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
rpsblast_cdd gnl|CDD|191813 3 284 + 282 Gaps:40 70.52 346 27.05 2e-17 pfam07690 MFS_1 Major Facilitator Superfamily.
rpsblast_cdd gnl|CDD|188094 7 283 + 277 Gaps:66 64.72 394 28.24 8e-12 TIGR00883 2A0106 metabolite-proton symporter. This model represents the metabolite:H+ symport subfamily of the major facilitator superfamily (pfam00083) including citrate-H+ symporters dicarboxylate:H+ symporters the proline/glycine-betaine transporter ProP etc.
rpsblast_cdd gnl|CDD|179668 9 144 + 136 Gaps:17 27.22 496 27.41 5e-11 PRK03893 PRK03893 putative sialic acid transporter Provisional.
rpsblast_cdd gnl|CDD|162085 4 136 + 133 Gaps:2 94.33 141 29.32 3e-10 TIGR00880 2_A_01_02 Multidrug resistance protein.

40 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 72 82 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 1 24 24 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 25 43 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 262 267 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 289 378 90 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 111 133 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 437 447 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Coils 159 180 22 Coil none none none
PANTHER 1 293 293 PTHR24063:SF299 none none none
PANTHER 371 505 135 PTHR24063:SF299 none none none
Phobius 106 110 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 201 290 90 G3DSA:1.20.1250.20 none none none
Gene3D 376 478 103 G3DSA:1.20.1250.20 none none none
Gene3D 4 142 139 G3DSA:1.20.1250.20 none none none
Phobius 448 466 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
TIGRFAM 2 294 293 TIGR00879 "Reactome:REACT_15518" SP: MFS transporter, sugar porter (SP) family IPR003663
SUPERFAMILY 3 289 287 SSF103473 none none IPR020846
SUPERFAMILY 376 479 104 SSF103473 none none IPR020846
Phobius 83 105 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 49 71 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
ProSitePatterns 55 80 26 PS00217 none Sugar transport proteins signature 2. IPR005829
Pfam 2 293 292 PF00083 none Sugar (and other) transporter IPR005828
Pfam 374 480 107 PF00083 none Sugar (and other) transporter IPR005828
Phobius 201 223 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 134 200 67 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 415 436 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PRINTS 50 69 20 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 405 417 13 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 382 403 22 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 211 221 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663

10 Localization

Analysis Start End Length
TMHMM 410 432 22
TMHMM 200 222 22
TMHMM 442 464 22
TMHMM 268 290 22
TMHMM 237 259 22
TMHMM 49 71 22
TMHMM 381 403 22
TMHMM 111 133 22
TMHMM 25 44 19
TMHMM 84 106 22

11 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran_2000_2002_QTL3_Delta.F Qrob_Chr08 8 s_1A3EF7_1406 s_1AIWYC_607 30.17 21,01 40,21 lod 6.8553 0.055
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nPriLBD_A4 Qrob_Chr08 8 PIE175 v_9164_159 31,85 15,39 48,29 lod 2,8308 6,8
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL3_d13Cf Qrob_Chr08 8 v_5216_549 v_11625_20 37.08 12,26 54,9 lod 6.5888 0.04

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 41   Secretory pathway 3 0.766 0.142 NON-PLANT 41