GRS - Genome Report System

Sclerotinia sclerotiorum GRS

Functional annotation

SS1G_03435.1

Gene Identifier

Domain/Motif (Interproscan results)

Localization / Targeting

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ssl:SS1G_03435	1	357	357	n/a	100.00	357	100.00	0.00	0.0	hypothetical protein
	bfu:BC1G_13892	59	312	254	Gaps:3	56.98	451	43.19	18.29	5e-54	hypothetical protein
	afv:AFLA_023550	65	349	285	Gaps:23	63.62	481	35.62	21.90	1e-47	MFS multidrug transporter putative
	aor:AO090001000505	59	349	291	n/a	52.63	551	38.62	20.00	8e-33	permeases of the major facilitator superfamily
	aor:AO090003001490	65	349	285	Gaps:2	50.87	574	36.99	24.32	9e-33	predicted transporter (major facilitator superfamily)
	ang:An04g10000	59	349	291	n/a	61.00	482	37.76	22.11	9e-33	hypothetical protein
	bfu:BC1G_11548	127	349	223	Gaps:7	66.09	348	32.61	23.48	8e-31	hypothetical protein
	fgr:FG04267.1	59	346	288	Gaps:20	64.50	462	31.54	19.80	9e-31	hypothetical protein
	mgr:MGCH7_ch7g429	59	341	283	Gaps:17	55.45	523	31.72	21.72	3e-28	MGG_ch7g429 hypothetical protein
	ncr:NCU09978	131	331	201	Gaps:7	81.57	255	36.06	18.27	8e-28	hypothetical protein
blastp_uniprot_sprot	sp\|Q9HE13\|YI32_SCHPO	59	135	77	n/a	13.07	589	37.66	23.38	1e-10	Uncharacterized MFS-type transporter C1399.02 OS Schizosaccharomyces pombe GN SPAC1399.02 PE 2 SV 1
	sp\|Q10072\|YAN6_SCHPO	59	135	77	n/a	13.07	589	37.66	23.38	3e-10	Uncharacterized transporter C3H1.06c OS Schizosaccharomyces pombe GN SPAC3H1.06c PE 2 SV 1
	sp\|P96712\|BMR3_BACSU	59	135	77	n/a	15.04	512	40.26	18.18	3e-10	Multidrug resistance protein 3 OS Bacillus subtilis GN bmr3 PE 1 SV 1
	sp\|O07753\|Y1877_MYCTU	59	151	93	Gaps:1	13.39	687	38.04	17.39	9e-10	Uncharacterized MFS-type transporter Rv1877/MT1926 OS Mycobacterium tuberculosis GN Rv1877 PE 3 SV 1
	sp\|P36172\|VBA5_YEAST	59	135	77	n/a	13.23	582	38.96	18.18	2e-09	Vacuolar basic amino acid transporter 5 OS Saccharomyces cerevisiae GN VBA5 PE 3 SV 1
	sp\|O32182\|YUSP_BACSU	1	135	135	Gaps:7	25.51	541	32.61	15.22	3e-09	Uncharacterized MFS-type transporter yusP OS Bacillus subtilis GN yusP PE 3 SV 1
	sp\|P25594\|VBA3_YEAST	63	135	73	n/a	15.94	458	38.36	19.18	1e-08	Vacuolar basic amino acid transporter 3 OS Saccharomyces cerevisiae GN VBA3 PE 1 SV 1
	sp\|P31474\|HSRA_ECOLI	64	135	72	n/a	15.16	475	38.89	19.44	2e-07	Probable transport protein hsrA OS Escherichia coli (strain K12) GN hsrA PE 1 SV 1
	sp\|P44903\|HSRA_HAEIN	59	135	77	n/a	16.63	463	37.66	18.18	1e-06	Probable transport protein hsrA OS Haemophilus influenzae GN hsrA PE 3 SV 1
blastp_pdb	no results
rpsblast_cdd	gnl\|CDD\|119392	59	284	226	Gaps:28	69.32	352	25.00	15.98	2e-15	cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
	gnl\|CDD\|148990	59	274	216	Gaps:55	76.23	345	20.53	16.35	4e-12	pfam07690 MFS_1 Major Facilitator Superfamily.
	gnl\|CDD\|129794	65	135	71	n/a	14.64	485	30.99	21.13	1e-08	TIGR00711 efflux_EmrB drug resistance transporter EmrB/QacA subfamily. This subfamily of drug efflux proteins a part of the major faciliator family is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae TcmA (tetracenomycin C resistance) in Streptomyces glaucescens etc. In most cases the efflux pump is described as having a second component encoded in the same operon such as EmrA of E. coli.
	gnl\|CDD\|162085	63	151	89	Gaps:1	62.41	141	31.82	13.64	4e-07	TIGR00880 2_A_01_02 Multidrug resistance protein.
	gnl\|CDD\|162095	59	133	75	n/a	18.84	398	30.67	14.67	8e-07	TIGR00895 2A0115 benzoate transport.
rpsblast_kog	no results

Other analysis

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