GRS - Genome Report System

Sclerotinia sclerotiorum GRS

Functional annotation

SS1G_00919.1

Gene Identifier

Domain/Motif (Interproscan results)

Localization / Targeting

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ssl:SS1G_00919	1	559	559	n/a	100.00	559	88.19	0.00	0.0	hypothetical protein
	bfu:BC1G_10036	1	558	558	n/a	96.88	576	77.78	3.58	0.0	hypothetical protein
	ure:UREG_03377	4	558	555	Gaps:15	94.57	571	49.81	16.11	1e-147	hypothetical protein
	cim:CIMG_08993	8	556	549	Gaps:16	93.67	569	50.47	16.14	1e-144	hypothetical protein
	afm:AFUA_1G16910	41	558	518	Gaps:9	90.73	561	51.28	14.93	1e-134	MFS multidrug transporter
	fgr:FG04188.1	15	558	544	Gaps:9	95.25	568	46.21	14.97	1e-130	hypothetical protein
	pan:PODANSg8452	47	553	507	Gaps:8	86.33	578	49.50	15.63	1e-127	hypothetical protein
	aor:AO090011000097	40	544	505	Gaps:18	96.94	523	47.53	16.96	1e-123	predicted transporter (major facilitator superfamily)
	afv:AFLA_039180	40	544	505	Gaps:18	96.94	523	47.34	17.16	1e-123	MFS gliotoxin efflux transporter GliA
	aor:AO090010000407	5	543	539	Gaps:22	94.54	549	44.51	17.53	1e-120	predicted transporter (major facilitator superfamily)
blastp_uniprot_sprot	sp\|Q00357\|TOXA_COCCA	57	555	499	Gaps:19	90.51	548	33.27	17.14	5e-60	Putative HC-toxin efflux carrier TOXA OS Cochliobolus carbonum GN TOXA PE 3 SV 1
	sp\|O42922\|YBIH_SCHPO	2	457	456	Gaps:7	75.63	599	25.83	16.78	7e-39	Uncharacterized MFS-type transporter C16A3.17c OS Schizosaccharomyces pombe GN SPBC16A3.17c PE 2 SV 1
	sp\|Q10072\|YAN6_SCHPO	21	513	493	Gaps:24	82.68	589	27.72	19.10	1e-38	Uncharacterized transporter C3H1.06c OS Schizosaccharomyces pombe GN SPAC3H1.06c PE 2 SV 1
	sp\|P36172\|VBA5_YEAST	47	457	411	Gaps:44	77.49	582	27.05	15.52	7e-37	Vacuolar basic amino acid transporter 5 OS Saccharomyces cerevisiae GN VBA5 PE 3 SV 1
	sp\|Q9HE13\|YI32_SCHPO	4	513	510	Gaps:16	87.95	589	26.83	16.99	2e-35	Uncharacterized MFS-type transporter C1399.02 OS Schizosaccharomyces pombe GN SPAC1399.02 PE 2 SV 1
	sp\|O32182\|YUSP_BACSU	56	457	402	Gaps:11	72.27	541	28.90	18.67	3e-31	Uncharacterized MFS-type transporter yusP OS Bacillus subtilis GN yusP PE 3 SV 1
	sp\|P96712\|BMR3_BACSU	67	457	391	Gaps:11	74.22	512	26.32	20.26	2e-29	Multidrug resistance protein 3 OS Bacillus subtilis GN bmr3 PE 1 SV 1
	sp\|P25594\|VBA3_YEAST	175	457	283	Gaps:44	70.52	458	28.79	14.24	7e-26	Vacuolar basic amino acid transporter 3 OS Saccharomyces cerevisiae GN VBA3 PE 1 SV 1
	sp\|P50080\|AZR1_YEAST	22	457	436	Gaps:52	79.61	613	25.20	15.16	2e-25	Azole resistance protein 1 OS Saccharomyces cerevisiae GN AZR1 PE 1 SV 1
	sp\|O07753\|Y1877_MYCTU	56	456	401	Gaps:10	56.91	687	26.85	14.83	7e-23	Uncharacterized MFS-type transporter Rv1877/MT1926 OS Mycobacterium tuberculosis GN Rv1877 PE 3 SV 1
blastp_pdb	no results
rpsblast_cdd	gnl\|CDD\|129794	55	474	420	Gaps:15	84.74	485	26.76	18.00	1e-39	TIGR00711 efflux_EmrB drug resistance transporter EmrB/QacA subfamily. This subfamily of drug efflux proteins a part of the major faciliator family is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae TcmA (tetracenomycin C resistance) in Streptomyces glaucescens etc. In most cases the efflux pump is described as having a second component encoded in the same operon such as EmrA of E. coli.
	gnl\|CDD\|148990	61	351	291	Gaps:9	86.96	345	23.00	17.67	4e-19	pfam07690 MFS_1 Major Facilitator Superfamily.
	gnl\|CDD\|170483	66	367	302	Gaps:15	61.78	471	28.52	17.87	2e-18	PRK10504 PRK10504 multidrug efflux system protein MdtE Provisional.
	gnl\|CDD\|119392	51	467	417	Gaps:72	100.00	352	41.76	25.57	2e-18	cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
	gnl\|CDD\|32643	49	268	220	Gaps:1	56.09	394	18.55	17.19	2e-12	COG2814 AraJ Arabinose efflux permease [Carbohydrate transport and metabolism].
	gnl\|CDD\|162085	120	232	113	n/a	80.14	141	30.09	15.93	2e-10	TIGR00880 2_A_01_02 Multidrug resistance protein.
	gnl\|CDD\|115279	190	474	285	Gaps:15	48.83	598	22.60	21.92	1e-09	pfam06609 TRI12 Fungal trichothecene efflux pump (TRI12). This family consists of several fungal specific trichothecene efflux pump proteins. Many of the genes involved in trichothecene toxin biosynthesis in Fusarium sporotrichioides are present within a gene cluster.It has been suggested that TRI12 may play a role in F. sporotrichioides self-protection against trichothecenes.
	gnl\|CDD\|162095	55	398	344	Gaps:41	79.65	398	25.55	16.40	3e-08	TIGR00895 2A0115 benzoate transport.
	gnl\|CDD\|167630	71	218	148	Gaps:16	30.49	492	27.33	20.67	4e-08	PRK03893 PRK03893 putative sialic acid transporter Provisional.
	gnl\|CDD\|162094	70	234	165	Gaps:3	41.60	399	23.49	15.06	2e-07	TIGR00893 2A0114 d-galactonate transporter.
rpsblast_kog	gnl\|CDD\|35475	30	441	412	Gaps:36	77.19	513	16.67	17.42	5e-17	KOG0254 KOG0254 KOG0254 Predicted transporter (major facilitator superfamily) [General function prediction only].
	gnl\|CDD\|35476	90	473	384	Gaps:34	67.95	521	18.08	15.54	8e-11	KOG0255 KOG0255 KOG0255 Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily) [General function prediction only].
	gnl\|CDD\|36544	42	234	193	Gaps:3	39.35	493	22.68	20.10	3e-09	KOG1330 KOG1330 KOG1330 Sugar transporter/spinster transmembrane protein [Carbohydrate transport and metabolism].
	gnl\|CDD\|37744	54	462	409	Gaps:58	76.16	495	20.95	15.12	4e-07	KOG2533 KOG2533 KOG2533 Permease of the major facilitator superfamily [Carbohydrate transport and metabolism].

Other analysis

Functional Gbrowse

Ortholog