GRS - Genome Report System

Botrytis cinerea T4 GRS

Functional annotation

BofuT4_P046910.1

Located on : bt4_SuperContig_34_1

Analysis	Type	ID	RefStart	RefEnd
egn5_orf	gene	BofuT4_G046910.1	666532	672607
	mRNA	BofuT4_T046910.1	666532	672607
	polypeptide	BofuT4_P046910.1	666532	672607

>BofuT4_P046910.1 | 1990 aa 
MEDGFQDDQNFYSRSFPQSEAQSPAQSQSQSQYSSDLTLQHRQIPPSTTCESPHFSQRFDFDPAPPHPPKLPLLTTSNLQLQTTNTHGYMNSSDDGGEPDDFYRDYQPLQQTNGPPDQLLDMAATTSDVRPASSTMRSSNTSSPPKQTPSTSRTTTRPPFGSNLSHAESNQKQSTKPLVNGYGKPSQKPSVKDLLKRFDQNNDQSLPMPRKPSVRTKDSAGISSGYMRDRSNPYSARVASNPGPTTTSSTLRASNTMREPGSTRVKSPSSSTRAMQRPRFATEDQQSSNASLGSARSMRTRNTPSTKSSSTSKSMNNLSPASQAQPPPAVPEKRPLFGEVSTLGQGTFEAGYGIPTATRRTSESGLPSVISTEQRSRTDADISPTSPTAWYLGVTPSLGDVEPNKPRRSGHNRAHSDFADTKVNTMHNVNRSSFLLPESPVNAKDSDPNIALDSSHVEAEGGFELQPPKLSSRLPIALKRSSTQSDGSSSPSTRASSPLTGKRALHGKVPRDHRPWSPAGRSMTSATRSVPPNSRAKTRSPDKVSSSGSLKAYISAPPAKNSPPLRSSRPRQPVSAATTASSRQKAVDGSASPHDTRAGIKATRASGTHETKGRKTTNTEPVNYAARRAQITRAYTKSIHESELQKIRASHAHHVNEQSTRATNGDKSPKSEHGNTSSSGDQIPDMPSPGPESLQILTSFDPQISPPPVEHQIVMDQDSPTLGVTNGMPGAFIEEDVPMSAISNISATTFIENEAQTEAARLARIPSIKLADSVAVPAQVFEVDDVTPEDRAKITTDSYRISVEETSIGTTPKEDFSKALPESIDHDLTSEASESPSNVVTYDDQAKDIVTDLPSAKKLASEIFNPTSMHHMNFEAAAPASINHDIVQPTGLGLYDESSQQLVDIPIRIEEDTDSSQLHSESDTYSGEGPRLELPALRTALAESLSPLENDRQPDLYTPTDIEYESSDDNRAGNTGNTSEQEDLYGPSYDQNRELYLTSDTYHRENRNSAWTDFSVATTDDPVSQDENQKWINTKISLPELQKAPTPPPKLPPSPGPLRLIEDTSSENSSRLELPPLTSHNGFGLGFDSDTIYSVPTVPVWSDLTPPLISEHTSRKDAIAKLGPPNRTPPPPAMQDSRPQSGTDQISQNTTSRHAESRRPSDDIVSPRPSLSTPSIFTPRSSMQISQEDVSLNNSYPAPKVPLLPLTEEEQAIAKKKSARLFTRRKIIEEIIDTESAYLKDMNVVEEIYKGTAEACPKLDFGDIKTIFRNTDEIIAFSTTLLDDLKKAGAAVYTSKARARQSKATSTTTTAANTPASLGPNDSSSDPPEFNDFNEERDRKTYIGYTFGKHLRRMQEVYTEFLKNSELAADRLKILSADPAVNVWLIECNNVAKDLTAAWDLDALMVKPVQRVTRYQLLIDNLVRHTAEDHPDFNALSIAARETLNLLQTIDRLKERISVVGKIVGRKRKESEVRLGIAKAFGRRSEKLTSNVVRPHDDEVFVKLHEKFGHDYLRLQVVMRDVEYYTRQVATWVNDFLRFLSAMEVVMRHSPSSHPEMEARWTQFNLSMRDMGSVALESHVGQIRKEVIEPIEAVIRLYSGPTEFMKKRAKRRVDYEKLMAVKANGKKPDEKLQLLAKEYDALNETLKTDMPRLSVLTAQIGQTILAKLIFSQTAWYYIWQEKVKTVLDANQIPMNENDILQSFERDYKYVLAQTQELRLINGTLEADCFLDRLDSTPVTSIKDNESIKTKGRLSDSSARPRVLSLAAPHDTSPCLPTPDFAKRHSGQFSFSPILSNGPGFPAHAPYQPAAYSVGHSRAGSGSPATPDASAPRLYGSTRPSTSRSITSDNGGMSRISTDLGHRRESSSTQASASYMVDGPLRDQRPFSGIFHSAMPLPDGPEDSVRSSRASSVDRAHRSRYNVIYLAASLFEFNIAATKTEAGYPYLTYSPGEIFDVIGEKGELWLAKNQDDGSDQVGWIWSKHFARLAMD

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	bfu:BC1G_00322	90	1990	1901	n/a	100.00	1901	92.53	0.00	0.0	hypothetical protein
	ssl:SS1G_04044	90	1990	1901	Gaps:28	100.00	1795	71.70	7.02	0.0	hypothetical protein
	mgr:MGG_11178	176	1988	1813	Gaps:240	73.80	2004	39.15	15.35	0.0	hypothetical protein
	pan:PODANSg10032	190	1988	1799	Gaps:139	58.44	2031	41.20	16.34	1e-173	hypothetical protein
	ncr:NCU10282	1216	1988	773	Gaps:86	36.47	2251	42.14	15.96	1e-165	hypothetical protein
	tml:GSTUM_00011040001	1221	1987	767	Gaps:68	42.58	1900	34.36	16.81	1e-131	hypothetical protein
	ani:AN3754.2	1220	1984	765	Gaps:26	26.25	2259	41.65	18.72	1e-108	hypothetical protein
	ang:An13g01180	1176	1988	813	Gaps:32	33.80	1938	40.76	19.85	1e-107	hypothetical protein
	afm:AFUA_7G04600	1170	1988	819	Gaps:44	34.79	1940	39.85	20.30	1e-107	Rho guanyl nucleotide exchange factor
	nfi:NFIA_025560	1186	1988	803	Gaps:28	33.57	1939	40.25	20.74	1e-106	Rho guanyl nucleotide exchange factor putative
blastp_uniprot_sprot	sp\|Q6XZF7\|DNMBP_HUMAN	1214	1726	513	Gaps:94	29.87	1577	25.69	21.23	6e-21	Dynamin-binding protein OS Homo sapiens GN DNMBP PE 1 SV 1
	sp\|Q6TXD4\|DNMBP_MOUSE	1221	1726	506	Gaps:75	29.56	1580	24.84	21.63	9e-20	Dynamin-binding protein OS Mus musculus GN Dnmbp PE 1 SV 2
	sp\|Q09763\|GEF1_SCHPO	1188	1605	418	Gaps:75	51.93	753	23.79	23.53	2e-16	Rho guanine nucleotide exchange factor gef1 OS Schizosaccharomyces pombe GN gef1 PE 1 SV 1
	sp\|A1IGU5\|ARH37_HUMAN	1221	1664	444	Gaps:84	58.37	675	23.10	22.08	2e-10	Rho guanine nucleotide exchange factor 37 OS Homo sapiens GN ARHGEF37 PE 2 SV 2
	sp\|Q96PE2\|ARHGH_HUMAN	1357	1457	101	Gaps:7	4.65	2063	37.50	22.92	1e-07	Rho guanine nucleotide exchange factor 17 OS Homo sapiens GN ARHGEF17 PE 1 SV 1
	sp\|Q553D3\|GXCJJ_DICDI	1356	1464	109	Gaps:3	9.04	1173	28.30	29.25	2e-07	Rac guanine nucleotide exchange factor JJ OS Dictyostelium discoideum GN gxcJJ PE 1 SV 1
	sp\|Q80U35\|ARHGH_MOUSE	1357	1457	101	Gaps:7	4.67	2057	37.50	22.92	2e-07	Rho guanine nucleotide exchange factor 17 OS Mus musculus GN Arhgef17 PE 1 SV 2
blastp_pdb	no results
rpsblast_cdd	gnl\|CDD\|153273	1496	1683	188	Gaps:3	94.87	195	35.68	24.86	2e-60	cd07589 BAR_DNMBP The Bin/Amphiphysin/Rvs (BAR) domain of Dynamin Binding Protein. BAR domains are dimerization lipid binding and curvature sensing modules found in many different proteins with diverse functions. DyNamin Binding Protein (DNMBP) also called Tuba is a Cdc42-specific Guanine nucleotide Exchange Factor (GEF) that binds dynamin and various actin regulatory proteins. It serves as a link between dynamin function Rho GTPase signaling and actin dynamics. It plays an important role in regulating cell junction configuration. DNMBP contains BAR and SH3 domains as well as a Dbl Homology domain (DH domain) which harbors GEF activity. BAR domains form dimers that bind to membranes induce membrane bending and curvature and may also be involved in protein-protein interactions. The BAR domain of DNMBP may be involved in binding to membranes. The gene encoding DNMBP is a candidate gene for late onset Alzheimer's disease.
	gnl\|CDD\|144276	1228	1451	224	Gaps:51	99.44	178	31.64	20.34	2e-26	pfam00621 RhoGEF RhoGEF domain. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that pfam00169 domains invariably occur C-terminal to RhoGEF/DH domains.
	gnl\|CDD\|29100	1224	1451	228	Gaps:49	100.00	181	27.07	23.20	3e-24	cd00160 RhoGEF Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains..
	gnl\|CDD\|128620	1227	1452	226	Gaps:48	100.00	180	30.56	23.33	1e-23	smart00325 RhoGEF Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases. Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains. Improved coverage.
	gnl\|CDD\|153283	1498	1686	189	Gaps:25	98.15	216	20.75	20.28	3e-09	cd07599 BAR_Rvs167p The Bin/Amphiphysin/Rvs (BAR) domain of Saccharomyces cerevisiae Reduced viability upon starvation protein 167 and similar proteins. BAR domains are dimerization lipid binding and curvature sensing modules found in many different proteins with diverse functions. This subfamily is composed of fungal proteins with similarity to Saccharomyces cerevisiae Reduced viability upon starvation protein 167 (Rvs167p) and Schizosaccharomyces pombe Hob1 (homolog of Bin1). S. cerevisiae Rvs167p plays a role in regulation of the actin cytoskeleton endocytosis and sporulation. It forms a heterodimer with another BAR domain protein Rvs161p. Rvs161p and Rvs167p share common functions but are not interchangeable. Their BAR domains cannot be replaced with each other and the overexpression of one cannot suppress the mutant phenotypes of the other. Rvs167p also interacts with the GTPase activating protein (GAP) Gyp5p which is involved in ER to Golgi vesicle trafficking. BAR domains form dimers that bind to membranes induce membrane bending and curvature and may also be involved in protein-protein interactions.
	gnl\|CDD\|145973	1500	1677	178	Gaps:52	90.43	230	17.31	21.63	2e-08	pfam03114 BAR BAR domain. BAR domains are dimerization lipid binding and curvature sensing modules found in many different protein families. A BAR domain with an additional N-terminal amphipathic helix (an N-BAR) can drive membrane curvature. These N-BAR domains are found in amphiphysin endophilin BRAP and Nadrin. BAR domains are also frequently found alongside domains that determine lipid specificity like pfam00169 and pfam00787 domains in beta centaurins and sorting nexins respectively.
rpsblast_kog	no results

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
RepeatMasker_ALL_Repbase	no results
TRF	no results
REPET	no results
sim4_Bot_allest	no results
sim4_Bot_allest4_clctg	no results
sim4_Ss_allest	no results
blastx_uniprot_sprot	no results
blastx_uniprot_trembl	A4RK43	666541	672316	2004	37.57	94.16	n/a	Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea)
	Q2HE55	666541	672328	1977	36.99	95.45	n/a	Putative uncharacterized protein - Chaetomium globosum (Soil fungus)
	A1CDE5	666541	672313	1955	30.79	95.86	n/a	Rho guanyl nucleotide exchange factor putative - Aspergillus clavatus
	A7UW66	666699	672316	2251	33.22	78.10	n/a	Predicted protein - Neurospora crassa
	A2R1G8	666541	672346	1938	33.55	72.45	n/a	Contig An13c0050 complete genome - Aspergillus niger
	A1DCC3	666541	669274	1939	35.00	45.38	n/a	Rho guanyl nucleotide exchange factor putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q1DQ79	666541	671824	1893	35.85	70.73	n/a	Putative uncharacterized protein - Coccidioides immitis
	Q0CPN5	666541	672418	1898	34.00	73.60	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
blastx_FNG30_prot	SS1G_04044.1	666535	672340	1795	77.94	100.00	n/a	sclerotinia_sclerotiorum hypothetical protein translation 1796 aa
	MGG_11178.5	666541	672316	2004	37.57	94.16	n/a	magnaporthe_grisea hypothetical protein translation 2005 aa
	CHG01499.1	666541	672328	1977	36.99	95.45	n/a	Chaetomium globosum hypothetical protein translation 1978 aa
	jgi:Triree:39002	666541	672373	1990	39.08	74.57	n/a	Trichoderma reesei
	NCU10282.2	666699	672316	2251	33.22	78.10	n/a	Neurospora crassa predicted protein translation 2252 aa
	gi:70987140:ref:XP_749050.1:	666541	671884	1940	33.18	67.58	n/a	Aspergillus fumigatus Af293 Rho guanyl nucleotide exchange factor
	AN10442	666541	672316	1921	33.17	75.01	n/a	Aspergillus nidulans AN10442.3 conserved hypothetical protein translation 1922 aa
	CIMG_07534.2	666541	671824	1893	35.85	70.73	n/a	Coccidioides immitis hypothetical protein translation 1894 aa
	AO090005000152	667865	671824	1538	34.87	55.01	n/a	Aspergillus oryzae invasion-inducing protein TIAM1/CDC24 and related RhoGEF GTPases
	SNU03468.1	666699	669418	1754	26.84	51.20	n/a	Stagonospora nodorum hypothetical protein translation
sim4_B0510_genes	BC1G_00322.1	666532	672340	5706	100.00	100.00	n/a	n/a
sim4_B0510_genes	BC1G_00322.1	666532	672340	5706	100.00	100.00	n/a	n/a
sim4_SS_genes	SS1G_04044.1	666532	672340	5388	84.11	74.15	n/a	n/a
sim4_SS_genes	SS1G_04044.1	666532	672340	5388	84.11	74.15	n/a	n/a
blastn_b0510_supercontig	B0510_supercontig_1.1	666072	673056	1306028	100.00	n/a	n/a	n/a
blastn_SS_supercontig	SS_supercontig_1.5	667868	668680	2230026	85.61	n/a	n/a	n/a
	SS_supercontig_1.5	671650	672328	2230026	82.77	n/a	n/a	n/a
	SS_supercontig_1.5	667087	667813	2230026	80.61	n/a	n/a	n/a
	SS_supercontig_1.5	669305	669838	2230026	81.65	n/a	n/a	n/a
	SS_supercontig_1.5	666696	667046	2230026	84.62	n/a	n/a	n/a
	SS_supercontig_1.5	668702	669018	2230026	85.49	n/a	n/a	n/a
	SS_supercontig_1.5	670796	671219	2230026	80.90	n/a	n/a	n/a
	SS_supercontig_1.5	666534	666652	2230026	94.12	n/a	n/a	n/a
	SS_supercontig_1.5	671246	671410	2230026	87.88	n/a	n/a	n/a
	SS_supercontig_1.5	670333	670485	2230026	84.97	n/a	n/a	n/a
	SS_supercontig_1.5	672473	672550	2230026	92.31	n/a	n/a	n/a
	SS_supercontig_1.5	672566	672874	2230026	83.55	n/a	n/a	n/a
blat_oligo	botrytisP00072235	668009	668068	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:9.15 . min_over_threshold:0.52 . percent_hyb_over_threshold:85.71 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072236	667742	667801	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:13.48 . min_over_threshold:0.62 . percent_hyb_over_threshold:92.85 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072237	667688	667747	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:13.56 . min_over_threshold:0.64 . percent_hyb_over_threshold:92.85 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072238	667562	667621	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:20.28 . min_over_threshold:0.82 . percent_hyb_over_threshold:92.85 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072239	667250	667309	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:31.54 . min_over_threshold:0.98 . percent_hyb_over_threshold:96.42 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072240	667087	667146	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:28.7 . min_over_threshold:1.02 . percent_hyb_over_threshold:100 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072241	666990	667049	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:28.02 . min_over_threshold:1.68 . percent_hyb_over_threshold:100 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:1
	botrytisP00072242	666890	666949	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:31.1 . min_over_threshold:0.89 . percent_hyb_over_threshold:96.42 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0
	botrytisP00072243	666767	666826	60	n/a	n/a	n/a	array_gene:BofuT4_P046910_1 . max_over_threshold:21.45 . min_over_threshold:0.95 . percent_hyb_over_threshold:96.42 . flag_cross_hyb_gene:0 . flag_cross_hyb_organism:0

Current manual annotation

Ortholog