GRS - Genome Report System

Botrytis cinerea B0510 GRS

Functional annotation

BC1G_10936.1

Gene Identifier

Domain/Motif (Interproscan results)

Localization / Targeting

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	bfu:BC1G_10936	1	448	448	n/a	100.00	448	95.54	0.00	0.0	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
	ssl:SS1G_08916	1	448	448	Gaps:1	87.66	535	88.70	3.41	1e-126	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
	ncr:NCU08216	9	445	437	Gaps:30	81.82	528	71.53	10.19	4e-90	cystathionine beta-synthase K01697 cystathionine beta-synthase [EC:4.2.1.22]
	pan:PODANSg4727	13	445	433	Gaps:25	79.36	533	73.05	9.93	1e-89	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
	fgr:FG06544.1	16	445	430	Gaps:20	80.66	517	70.74	13.43	2e-86	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
	pno:SNOG_12735	1	445	445	Gaps:24	85.77	534	64.63	12.66	2e-83	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
	mgr:MGG_07384	16	447	432	Gaps:29	82.58	528	69.95	11.70	4e-83	MG07384.4 similar to cystathionine beta synthase K01697 cystathionine beta-synthase [EC:4.2.1.22]
	afv:AFLA_047240	1	445	445	Gaps:26	92.82	529	59.27	13.65	2e-82	cystathionine beta-synthase putative K01697 cystathionine beta-synthase [EC:4.2.1.22]
	aor:AO090011000931	1	248	248	Gaps:18	78.47	339	60.15	10.53	3e-82	cysteine synthase K01697 cystathionine beta-synthase [EC:4.2.1.22]
	ani:AN5820.2	1	447	447	Gaps:8	84.11	535	64.44	12.22	2e-81	hypothetical protein K01697 cystathionine beta-synthase [EC:4.2.1.22]
blastp_uniprot_sprot	sp\|P32582\|CBS_YEAST	19	442	424	Gaps:37	71.60	507	54.55	16.25	9e-63	Cystathionine beta-synthase OS Saccharomyces cerevisiae GN CYS4 PE 1 SV 1
	sp\|P46794\|CBS_DICDI	21	444	424	Gaps:55	67.27	498	60.00	16.72	8e-62	Cystathionine beta-synthase OS Dictyostelium discoideum GN cysB PE 2 SV 2
	sp\|P32232\|CBS_RAT	5	349	345	Gaps:13	52.76	561	53.38	16.55	1e-61	Cystathionine beta-synthase OS Rattus norvegicus GN Cbs PE 1 SV 3
	sp\|Q91WT9\|CBS_MOUSE	21	349	329	Gaps:13	49.91	561	55.71	16.43	3e-61	Cystathionine beta-synthase OS Mus musculus GN Cbs PE 2 SV 3
	sp\|P35520\|CBS_HUMAN	5	447	443	Gaps:58	65.52	551	48.48	17.73	4e-61	Cystathionine beta-synthase OS Homo sapiens GN CBS PE 1 SV 2
	sp\|Q9N0V7\|CBS_RABIT	8	442	435	Gaps:58	64.07	551	49.58	18.98	1e-60	Cystathionine beta-synthase OS Oryctolagus cuniculus GN CBS PE 2 SV 3
	sp\|Q58H57\|CBS_MACFA	5	354	350	Gaps:13	54.99	551	52.48	16.83	5e-60	Cystathionine beta-synthase OS Macaca fascicularis GN CBS PE 2 SV 3
	sp\|Q7D8W0\|Y1077_MYCTU	13	178	166	Gaps:4	35.34	464	51.22	14.02	4e-37	Putative cystathionine beta-synthase Rv1077 OS Mycobacterium tuberculosis GN cbs PE 1 SV 1
	sp\|Q7DDL5\|CYSK_NEIMB	13	178	166	Gaps:6	52.26	310	51.23	17.90	2e-36	Cysteine synthase OS Neisseria meningitidis serogroup B GN cysK PE 1 SV 1
	sp\|P73410\|CYSK_SYNY3	13	179	167	Gaps:4	52.88	312	49.09	16.97	2e-35	Cysteine synthase OS Synechocystis sp. (strain PCC 6803) GN cysK PE 3 SV 2
blastp_pdb	1m54_F	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1m54_E	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1m54_D	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1m54_C	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1m54_B	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1m54_A	5	180	176	n/a	48.48	363	63.64	16.48	4e-62	mol:protein length:363 CYSTATHIONINE BETA-SYNTHASE
	1jbq_F	5	180	176	n/a	40.46	435	63.64	16.48	2e-61	mol:protein length:435 CYSTATHIONINE BETA-SYNTHASE
	1jbq_E	5	180	176	n/a	40.46	435	63.64	16.48	2e-61	mol:protein length:435 CYSTATHIONINE BETA-SYNTHASE
	1jbq_D	5	180	176	n/a	40.46	435	63.64	16.48	2e-61	mol:protein length:435 CYSTATHIONINE BETA-SYNTHASE
	1jbq_C	5	180	176	n/a	40.46	435	63.64	16.48	2e-61	mol:protein length:435 CYSTATHIONINE BETA-SYNTHASE
rpsblast_cdd	gnl\|CDD\|162220	16	442	427	Gaps:62	79.96	454	58.40	15.70	4e-90	TIGR01137 cysta_beta cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven.
	gnl\|CDD\|107204	22	213	192	Gaps:3	64.95	291	60.85	12.17	3e-84	cd01561 CBS_like CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine..
	gnl\|CDD\|30381	16	213	198	Gaps:5	65.00	300	56.41	14.36	3e-69	COG0031 CysK Cysteine synthase [Amino acid transport and metabolism].
	gnl\|CDD\|162219	18	217	200	Gaps:5	65.22	299	54.36	13.85	6e-67	TIGR01136 cysKM cysteine synthases. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff.
	gnl\|CDD\|170656	18	213	196	Gaps:8	59.46	333	48.48	17.17	1e-61	PRK10717 PRK10717 cysteine synthase A Provisional.
	gnl\|CDD\|162221	18	216	199	Gaps:7	65.10	298	52.06	15.46	4e-60	TIGR01139 cysK cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate.
	gnl\|CDD\|171272	19	213	195	Gaps:12	64.07	295	50.26	14.81	1e-57	PRK11761 cysM cysteine synthase B Provisional.
	gnl\|CDD\|107202	24	213	190	Gaps:10	74.59	244	42.86	15.93	1e-50	cd00640 Trp-synth-beta_II Tryptophan synthase beta superfamily (fold type II) this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD) tryptophan synthase beta chain (Trp-synth_B) cystathionine beta-synthase (CBS) O-acetylserine sulfhydrylase (CS) serine dehydratase (Ser-dehyd) threonine dehydratase (Thr-dehyd) diaminopropionate ammonia lyase (DAL) and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha beta-elimination reaction of both L- and D-alpha beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine..
	gnl\|CDD\|130208	19	217	199	Gaps:6	66.55	290	48.19	16.06	3e-50	TIGR01138 cysM cysteine synthase B. Alternate name: O-acetylserine (thiol)-lyase.
	gnl\|CDD\|166206	13	213	201	Gaps:8	61.18	322	49.75	14.72	5e-46	PLN02565 PLN02565 O-acetylserine (thiol) lyase.
rpsblast_kog	gnl\|CDD\|36466	7	213	207	Gaps:3	56.91	362	57.28	12.14	3e-71	KOG1252 KOG1252 KOG1252 Cystathionine beta-synthase and related enzymes [Amino acid transport and metabolism].
	gnl\|CDD\|36694	19	210	192	Gaps:9	49.87	391	44.10	13.85	5e-45	KOG1481 KOG1481 KOG1481 Cysteine synthase [Amino acid transport and metabolism].
	gnl\|CDD\|36464	12	207	196	Gaps:28	40.26	457	29.35	13.59	4e-10	KOG1250 KOG1250 KOG1250 Threonine/serine dehydratases [Amino acid transport and metabolism].
	gnl\|CDD\|36465	19	213	195	Gaps:15	56.35	323	31.32	15.38	2e-07	KOG1251 KOG1251 KOG1251 Serine racemase [Signal transduction mechanisms Amino acid transport and metabolism].

Other analysis

Functional Gbrowse

Ortholog