GRS - Genome Report System

Botrytis cinerea B0510 GRS

Functional annotation

BC1G_09723.1

Gene Identifier

Domain/Motif (Interproscan results)

Localization / Targeting

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	bfu:BC1G_09723	1	366	366	n/a	100.00	366	96.72	0.00	0.0	hypothetical protein
	ssl:SS1G_01347	1	335	335	n/a	51.38	652	100.00	0.00	0.0	hypothetical protein
	fgr:FG06165.1	1	335	335	n/a	50.91	658	88.36	5.67	1e-178	hypothetical protein
	ani:AN5865.2	1	335	335	n/a	51.07	656	87.16	7.16	1e-178	hypothetical protein
	ang:An02g03520	1	335	335	n/a	51.15	655	87.16	6.87	1e-177	hypothetical protein
	aor:AO090026000495	1	335	335	n/a	51.15	655	85.37	8.66	1e-176	GTP-binding protein CRFG/NOG1 (ODN superfamily)
	act:ACLA_070470	1	335	335	n/a	51.15	655	86.57	6.87	1e-176	nucleolar GTP-binding protein
	nfi:NFIA_086760	1	335	335	n/a	51.15	655	86.27	7.46	1e-176	nucleolar GTP-binding protein
	cim:CIMG_08196	1	335	335	n/a	51.07	656	87.76	4.78	1e-176	hypothetical protein
	ure:UREG_02446	1	335	335	Gaps:17	52.30	673	83.24	4.83	1e-172	nucleolar GTP-binding protein 1
blastp_uniprot_sprot	sp\|Q74ZK6\|NOG1_ASHGO	1	335	335	n/a	52.18	642	70.45	13.43	1e-145	Nucleolar GTP-binding protein 1 OS Ashbya gossypii GN NOG1 PE 3 SV 1
	sp\|O94659\|NOG1_SCHPO	3	335	333	n/a	51.87	642	70.57	12.31	1e-142	Probable nucleolar GTP-binding protein 1 OS Schizosaccharomyces pombe GN nog1 PE 1 SV 2
	sp\|Q02892\|NOG1_YEAST	1	335	335	n/a	51.78	647	68.96	13.73	1e-141	Nucleolar GTP-binding protein 1 OS Saccharomyces cerevisiae GN NOG1 PE 1 SV 1
	sp\|Q6FRV0\|NOG1_CANGA	1	335	335	n/a	51.94	645	69.25	13.13	1e-141	Nucleolar GTP-binding protein 1 OS Candida glabrata GN NOG1 PE 3 SV 1
	sp\|Q6CM00\|NOG1_KLULA	1	335	335	n/a	52.10	643	67.46	14.63	1e-139	Nucleolar GTP-binding protein 1 OS Kluyveromyces lactis GN NOG1 PE 3 SV 1
	sp\|Q9V411\|NOG1_DROME	4	335	332	n/a	50.92	652	60.54	20.18	1e-125	Probable nucleolar GTP-binding protein 1 OS Drosophila melanogaster GN CG8801 PE 2 SV 1
	sp\|Q9BZE4\|NOG1_HUMAN	4	335	332	Gaps:1	52.21	634	61.33	17.52	1e-121	Nucleolar GTP-binding protein 1 OS Homo sapiens GN GTPBP4 PE 1 SV 3
	sp\|Q99ME9\|NOG1_MOUSE	4	335	332	Gaps:1	52.21	634	61.63	17.22	1e-121	Nucleolar GTP-binding protein 1 OS Mus musculus GN Gtpbp4 PE 2 SV 3
	sp\|Q54N72\|NOG1_DICDI	4	335	332	Gaps:5	50.00	674	60.83	17.80	1e-120	Probable nucleolar GTP-binding protein 1 OS Dictyostelium discoideum GN nog1 PE 1 SV 1
	sp\|Q99P77\|NOG1_RAT	4	335	332	Gaps:1	51.96	637	61.03	17.52	1e-119	Nucleolar GTP-binding protein 1 OS Rattus norvegicus GN Gtpbp4 PE 2 SV 3
blastp_pdb	2e87_A	1	361	361	Gaps:5	99.72	357	30.62	21.91	3e-49	mol:protein length:357 Hypothetical protein PH1320
	2qu8_A	160	335	176	Gaps:2	78.07	228	47.19	21.35	1e-44	mol:protein length:228 Putative nucleolar GTP-binding protein 1
	1udx_A	172	334	163	Gaps:8	37.74	416	30.57	22.29	5e-11	mol:protein length:416 the GTP-binding protein Obg
rpsblast_cdd	gnl\|CDD\|31281	1	336	336	Gaps:2	97.11	346	40.77	19.64	1e-115	COG1084 COG1084 Predicted GTPase [General function prediction only].
	gnl\|CDD\|133297	168	337	170	Gaps:5	98.21	168	60.61	15.15	2e-80	cd01897 NOG NOG1 is a nucleolar GTP-binding protein present in eukaryotes ranging from trypanosomes to humans. NOG1 is functionally linked to ribosome biogenesis and found in association with the nuclear pore complexes and identified in many preribosomal complexes. Thus defects in NOG1 can lead to defects in 60S biogenesis. The S. cerevisiae NOG1 gene is essential for cell viability and mutations in the predicted G motifs abrogate function. It is a member of the ODN family of GTP-binding proteins that also includes the bacterial Obg and DRG proteins.
	gnl\|CDD\|133281	172	336	165	Gaps:18	98.30	176	27.17	15.03	4e-33	cd01881 Obg_like The Obg-like subfamily consists of five well-delimited ancient subfamilies namely Obg DRG YyaF/YchF Ygr210 and NOG1. Four of these groups (Obg DRG YyaF/YchF and Ygr210) are characterized by a distinct glycine-rich motif immediately following the Walker B motif (G3 box). Obg/CgtA is an essential gene that is involved in the initiation of sporulation and DNA replication in the bacteria Caulobacter and Bacillus but its exact molecular role is unknown. Furthermore several OBG family members possess a C-terminal RNA-binding domain the TGS domain which is also present in threonyl-tRNA synthetase and in bacterial guanosine polyphosphatase SpoT. Nog1 is a nucleolar protein that might function in ribosome assembly. The DRG and Nog1 subfamilies are ubiquitous in archaea and eukaryotes the Ygr210 subfamily is present in archaea and fungi and the Obg and YyaF/YchF subfamilies are ubiquitous in bacteria and eukaryotes. The Obg/Nog1 and DRG subfamilies appear to form one major branch of the Obg family and the Ygr210 and YchF subfamilies form another branch. No GEFs GAPs or GDIs for Obg have been identified.
	gnl\|CDD\|115510	234	291	58	n/a	100.00	58	60.34	20.69	2e-23	pfam06858 NOG1 Nucleolar GTP-binding protein 1 (NOG1). This family represents a conserved region of approximately 60 residues in length within nucleolar GTP-binding protein 1 (NOG1). In S. cerevisiae the NOG1 gene has been shown to be essential for cell viability suggesting that NOG1 may play an important role in nucleolar functions. Family members include eukaryotic bacterial and archaeal proteins.
	gnl\|CDD\|133256	172	336	165	Gaps:9	98.16	163	24.38	18.12	1e-14	cd00880 Era_like Era (E. coli Ras-like protein)-like. This family includes several distinct subfamilies (TrmE/ThdF FeoB YihA (EngG) Era and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs) to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes but is absent from archaea. The yeast member of TrmE family MSS1 is involved in mitochondrial translation bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and since the sequences of the two domains are more similar to each other than to other GTPases it is likely that an ancient gene duplication rather than a fusion of evolutionarily distinct GTPases gave rise to this family.
	gnl\|CDD\|133298	174	334	161	Gaps:50	93.53	170	27.67	13.84	4e-13	cd01898 Obg Obg subfamily. The Obg nucleotide binding protein subfamily has been implicated in stress response chromosome partitioning replication initiation mycelium development and sporulation. Obg proteins are among a large group of GTP binding proteins conserved from bacteria to humans. The E. coli homolog ObgE is believed to function in ribosomal biogenesis. Members of the subfamily contain two equally and highly conserved domains a C-terminal GTP binding domain and an N-terminal glycine-rich domain.
	gnl\|CDD\|30882	174	334	161	Gaps:29	43.90	369	29.01	13.58	3e-11	COG0536 Obg Predicted GTPase [General function prediction only].
	gnl\|CDD\|30833	170	334	165	Gaps:22	33.26	454	27.81	21.19	1e-10	COG0486 ThdF Predicted GTPase [General function prediction only].
	gnl\|CDD\|133258	172	336	165	Gaps:15	99.36	157	21.79	19.23	2e-10	cd00882 Ras_like_GTPase Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras Rho Rab and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors Era-like GTPases and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression the Rho family regulates cytoskeletal reorganization and gene expression the Rab and Sar1/Arf families regulate vesicle trafficking and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulate initiation elongation termination and release in translation and the Era-like GTPase family regulates cell division sporulation and DNA replication. Members of the Ras superfamily are identified by the GTP binding site which is made up of five characteristic sequence motifs and the switch I and switch II regions.
	gnl\|CDD\|133296	174	226	53	n/a	22.75	233	39.62	20.75	4e-09	cd01896 DRG The developmentally regulated GTP-binding protein (DRG) subfamily is an uncharacterized member of the Obg family an evolutionary branch of GTPase superfamily proteins. GTPases act as molecular switches regulating diverse cellular processes. DRG2 and DRG1 comprise the DRG subfamily in eukaryotes. In view of their widespread expression in various tissues and high conservation among distantly related species in eukaryotes and archaea DRG proteins may regulate fundamental cellular processes. It is proposed that the DRG subfamily proteins play their physiological roles through RNA binding.
rpsblast_kog	gnl\|CDD\|36703	1	336	336	n/a	54.19	620	68.15	11.90	1e-144	KOG1490 KOG1490 KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily) [General function prediction only].
	gnl\|CDD\|36702	174	334	161	Gaps:20	43.44	366	30.82	19.50	4e-11	KOG1489 KOG1489 KOG1489 Predicted GTP-binding protein (ODN superfamily) [General function prediction only].
	gnl\|CDD\|36405	170	334	165	Gaps:17	32.77	531	24.14	15.52	1e-09	KOG1191 KOG1191 KOG1191 Mitochondrial GTPase [Translation ribosomal structure and biogenesis].

Other analysis

Functional Gbrowse

Ortholog