| Analysis | rpsblast_cdd | Start | 1 |
| End | 105 | Strand | + |
| Length | 105 | Note | Gaps:2 |
| Hit Coverage | 44.21 | Hit Length | 233 |
| Hit Pident | 48.54 | E Val | 3e-35 |
| Hit Description | cd09869 PIN_GEN1 PIN domain of Gap Endonuclease 1 a structure-specific divalent-metal-ion dependent 5' nuclease and homologs. Gap Endonuclease 1 (GEN1) is a Holliday junction resolvase reported to symmetrically cleave Holliday junctions and allow religation without additional processing. GEN1 is a member of the structure-specific 5' nuclease family that catalyzes hydrolysis of DNA duplex-containing nucleic acid structures during DNA replication repair and recombination. These nucleases contain a PIN (PilT N terminus) domain with a helical arch/clamp region (I domain) of variable length (approximately 30 - 50 residues in GEN1 PIN domains) and a H3TH (helix-3-turn-helix) domain an atypical helix-hairpin-helix-2-like region. Both the H3TH domain (not included here) and the helical arch/clamp region are involved in DNA binding. Nucleases within this group also have a carboxylate-rich active site that is involved in binding essential divalent metal ion cofactors (Mg2+/Mn2+). | Hit Pcons | 9.71 |
| Name | Qrob_P0612720.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0612720.2 | Quercus robur | 100.0 | egn | (M=3) K15338 - flap endonuclease GEN [EC:3.1.-.-] | validated |
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