| Analysis | rpsblast_cdd | Start | 152 |
| End | 234 | Strand | + |
| Length | 83 | Note | Gaps:14 |
| Hit Coverage | 100.00 | Hit Length | 97 |
| Hit Pident | 51.55 | E Val | 6e-28 |
| Hit Description | pfam05093 CIAPIN1 Cytokine-induced anti-apoptosis inhibitor 1 Fe-S biogenesis. Anamorsin subsequently named CIAPIN1 for cytokine-induced anti-apoptosis inhibitor 1 in humans is the homologue of yeast Dre2 a conserved soluble eukaryotic Fe-S cluster protein that functions in cytosolic Fe-S protein biogenesis. It is found in both the cytoplasm and in the mitochondrial intermembrane space (IMS). CIAPIN1 is found to be up-regulated in hepatocellular cancer is considered to be a downstream effector of the receptor tyrosine kinase-Ras signalling pathway and is essential in mouse definitive haematopoiesis. Dre2 has been found to interact with the yeast reductase Tah18 forming a tight cytosolic complex implicated in the response to high levels of oxidative stress. | Hit Pcons | 5.15 |
| Name | Qrob_P0538090.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0538090.2 | Quercus robur | 100.0 | egn | (M=2) KOG4020 - Protein DRE2 required for cell viability [Function unknown]. | validated |
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