| Analysis | rpsblast_cdd | Start | 11 |
| End | 94 | Strand | + |
| Length | 84 | Note | Gaps:5 |
| Hit Coverage | 28.80 | Hit Length | 309 |
| Hit Pident | 38.20 | E Val | 3e-12 |
| Hit Description | pfam01207 Dus Dihydrouridine synthase (Dus). Members of this family catalyze the reduction of the 5 6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes and also in some archae. Most dihydrouridines are found in the D loop of t-RNAs. The role of dihydrouridine in tRNA is currently unknown but may increase conformational flexibility of the tRNA. It is likely that different family members have different substrate specificities which may overlap. Dus 1 from Saccharomyces cerevisiae acts on pre-tRNA-Phe while Dus 2 acts on pre-tRNA-Tyr and pre-tRNA-Leu. Dus 1 is active as a single subunit requiring NADPH or NADH and is stimulated by the presence of FAD. Some family members may be targeted to the mitochondria and even have a role in mitochondria. | Hit Pcons | 6.74 |
| Name | Qrob_P0515700.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0515700.2 | Quercus robur | 76.5 | egn | (M=2) 1.3.1.91 - tRNA-dihydrouridine(20) synthase (NAD(P)(+)). | EC:1.3.1.91 | validated |
Powered by
