| Analysis | rpsblast_cdd | Start | 1 |
| End | 166 | Strand | + |
| Length | 166 | Note | Gaps:22 |
| Hit Coverage | 100.00 | Hit Length | 176 |
| Hit Pident | 33.52 | E Val | 4e-32 |
| Hit Description | pfam03105 SPX SPX domain. We have named this region the SPX domain after (SYG1 Pho81 and XPR1). This 180 residue length domain is found at the amino terminus of a variety of proteins. In the yeast protein SYG1 the N-terminus directly binds to the G- protein beta subunit and inhibits transduction of the mating pheromone signal. This finding suggests that all the members of this family are involved in G-protein associated signal transduction. The N-termini of several proteins involved in the regulation of phosphate transport including the putative phosphate level sensors PHO81 from Saccharomyces cerevisiae and NUC-2 from Neurospora crassa are also members of this family. The SPX domain of S. cerevisiae low-affinity phosphate transporters Pho87 and Pho90 auto-regulates uptake and prevents efflux. This SPX dependent inhibition is mediated by the physical interaction with Spl2 NUC-2 contains several ankyrin repeats pfam00023. Several members of this family are annotated as XPR1 proteins: the xenotropic and polytropic retrovirus receptor confers susceptibility to infection with murine leukaemia viruses (MLV). The similarity between SYG1 phosphate regulators and XPR1 sequences has been previously noted as has the additional similarity to several predicted proteins of unknown function from Drosophila melanogaster Arabidopsis thaliana Caenorhabditis elegans Schizosaccharomyces pombe and Saccharomyces cerevisiae. In addition given the similarities between XPR1 and SYG1 and phosphate regulatory proteins it has been proposed that XPR1 might be involved in G-protein associated signal transduction and may itself function as a phosphate sensor. | Hit Pcons | 22.73 |
| Name | Qrob_P0387800.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0387800.2 | Quercus robur | 61.2 | egn | (M=1) PTHR10783//PTHR10783:SF26 - XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED // SUBFAMILY NOT NAMED | validated |
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