Blast Analysis : gnl|CDD|211659

Analysis	rpsblast_cdd	Start	1
End	151	Strand	+
Length	151	Note	Gaps:16
Hit Coverage	74.21	Hit Length	190
Hit Pident	31.91	E Val	2e-34
Hit Description	TIGR01489 DKMTPPase-SF 2 3-diketo-5-methylthio-1-phosphopentane phosphatase. This phosphatase is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. With the exception of OMNI\|NTL01BS01361 from B. subtilis and GP\|15024582 from Clostridium acetabutylicum the members of this group are all eukaryotic spanning metazoa plants and fungi. The B. subtilus gene (YkrX renamed MtnX) is part of an operon for the conversion of methylthioribose (MTR) to methionine. It works with the enolase MtnW a RuBisCO homolog. The combination of MtnW and MtnX achieves the same overall reaction as the enolase-phosphatase MtnC. The function of MtnX was shown by Ashida et al. (2003) to be 2 3-diketo-5-methylthio-1-phosphopentane phosphatase rather than 2 3-diketo-5-methylthio-1-phosphopentane phosphatase as proposed earlier. See the Genome Property for methionine salvage for more details. In eukaryotes methionine salvage from methylthioadenosine also occurs. It seems reasonable that members of this family in eukaryotes fulfill a similar role as in Bacillus. A more specific equivalog-level model is TIGR03333. Note that a member of this family from S. cerevisiae is annotated as a "probable membrane protein" due to a predicted transmembrane helix. The region in question contains the second of the three conserved HAD superfamily catalytic motifs and thus considering the fold of the HAD catalytic domain is unlikely to be a transmembrane region in fact.	Hit Pcons	20.57
Name	Qrob_P0280830.2

1 Protein

Protein Identifier	Organism . Name	Score	Score Type	Protein Description	Alias (in v1)	Code Enzyme	Gene Prediction Quality
Qrob_P0280830.2	Quercus robur	100.0	egn	(M=4) K13248 - pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74]		EC:3.6.1.1	validated

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