| Analysis | rpsblast_cdd | Start | 9 |
| End | 170 | Strand | + |
| Length | 162 | Note | Gaps:4 |
| Hit Coverage | 100.00 | Hit Length | 158 |
| Hit Pident | 55.06 | E Val | 2e-61 |
| Hit Description | cd04015 C2_plant_PLD C2 domain present in plant phospholipase D (PLD). PLD hydrolyzes terminal phosphodiester bonds in diester glycerophospholipids resulting in the degradation of phospholipids. In vitro PLD transfers phosphatidic acid to primary alcohols. In plants PLD plays a role in germination seedling growth phosphatidylinositol metabolism and changes in phospholipid composition. There is a single Ca(2+)/phospholipid-binding C2 domain in PLD. C2 domains fold into an 8-standed beta-sandwich that can adopt 2 structural arrangements: Type I and Type II distinguished by a circular permutation involving their N- and C-terminal beta strands. Many C2 domains are Ca2+-dependent membrane-targeting modules that bind a wide variety of substances including bind phospholipids inositol polyphosphates and intracellular proteins. Most C2 domain proteins are either signal transduction enzymes that contain a single C2 domain such as protein kinase C or membrane trafficking proteins which contain at least two C2 domains such as synaptotagmin 1. However there are a few exceptions to this including RIM isoforms and some splice variants of piccolo/aczonin and intersectin which only have a single C2 domain. C2 domains with a calcium binding region have negatively charged residues primarily aspartates that serve as ligands for calcium ions. | Hit Pcons | 11.39 |
| Name | Qrob_P0204290.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0204290.2 | Quercus robur | 99.0 | egn | (M=2) PF00168//PF00614 - C2 domain // Phospholipase D Active site motif | EC:3.1.4.4 | validated |
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