Protein : Qrob_P0762970.2 Q. robur
Protein Identifier  ? Qrob_P0762970.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) PTHR11772:SF3 - ASPARAGINE SYNTHETASE Gene Prediction Quality  validated
Protein length 

Sequence

Length: 693  
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.
GO:0006529 asparagine biosynthetic process The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.

27 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103342051 1 686 + 686 Gaps:24 99.10 670 72.89 0.0 asparagine synthetase domain-containing protein 1
blastp_kegg lcl|pper:PRUPE_ppa023466mg 1 686 + 686 Gaps:28 99.11 676 72.09 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_011520 1 692 + 692 Gaps:48 100.00 644 72.52 0.0 Asparagine synthase family protein putative
blastp_kegg lcl|mdm:103425457 1 686 + 686 Gaps:30 99.40 662 72.04 0.0 asparagine synthetase domain-containing protein 1-like
blastp_kegg lcl|mdm:103402815 1 686 + 686 Gaps:30 99.40 662 72.04 0.0 asparagine synthetase domain-containing protein 1
blastp_kegg lcl|cit:102614567 1 686 + 686 Gaps:46 99.23 649 72.05 0.0 asparagine synthetase domain-containing protein 1-like
blastp_kegg lcl|cic:CICLE_v10033727mg 1 686 + 686 Gaps:46 99.23 649 72.20 0.0 hypothetical protein
blastp_kegg lcl|mdm:103451761 1 681 + 681 Gaps:33 97.18 673 70.80 0.0 asparagine synthetase domain-containing protein 1-like
blastp_kegg lcl|gmx:100801355 1 691 + 691 Gaps:43 99.85 653 68.56 0.0 asparagine synthetase domain-containing protein 1-like
blastp_kegg lcl|fve:101310118 1 686 + 686 Gaps:73 99.84 618 73.91 0.0 asparagine synthetase domain-containing protein 1-like
blastp_uniprot_sprot sp|Q9NWL6|ASND1_HUMAN 118 662 + 545 Gaps:125 88.96 643 37.94 2e-98 Asparagine synthetase domain-containing protein 1 OS Homo sapiens GN ASNSD1 PE 2 SV 2
blastp_uniprot_sprot sp|Q4R5D4|ASND1_MACFA 118 662 + 545 Gaps:125 88.96 643 37.76 3e-98 Asparagine synthetase domain-containing protein 1 OS Macaca fascicularis GN ASNSD1 PE 2 SV 1
blastp_uniprot_sprot sp|Q0V8E4|ASND1_BOVIN 118 662 + 545 Gaps:134 89.53 640 37.17 1e-94 Asparagine synthetase domain-containing protein 1 OS Bos taurus GN ASNSD1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8JFW1|ASND1_DANRE 126 673 + 548 Gaps:100 91.18 612 36.20 1e-91 Asparagine synthetase domain-containing protein 1 OS Danio rerio GN asnsd1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8BFS9|ASND1_MOUSE 126 667 + 542 Gaps:137 90.43 627 37.21 7e-91 Asparagine synthetase domain-containing protein 1 OS Mus musculus GN Asnsd1 PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZJN0|ASND1_CHICK 116 665 + 550 Gaps:72 65.72 636 43.78 2e-61 Asparagine synthetase domain-containing protein 1 OS Gallus gallus GN ASNSD1 PE 2 SV 1
blastp_uniprot_sprot sp|O74397|ASND1_SCHPO 124 662 + 539 Gaps:122 88.14 548 34.78 2e-60 Asparagine synthetase domain-containing protein C4F6.11c OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN SPBC4F6.11c PE 3 SV 1
blastp_uniprot_sprot sp|Q5LJP9|ASND1_DROME 110 676 + 567 Gaps:96 94.15 564 30.70 8e-49 Asparagine synthetase domain-containing protein CG17486 OS Drosophila melanogaster GN CG17486 PE 2 SV 2
blastp_uniprot_sprot sp|Q04489|ASND1_YEAST 363 668 + 306 Gaps:48 55.24 525 37.93 3e-33 Asparagine synthetase domain-containing protein YML096W OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN YML096W PE 1 SV 1
blastp_uniprot_sprot sp|Q58516|ASNH1_METJA 538 658 + 121 Gaps:27 27.36 541 35.81 6e-13 Putative asparagine synthetase [glutamine-hydrolyzing] 1 OS Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) GN MJ1116 PE 3 SV 1
rpsblast_cdd gnl|CDD|48484 123 286 + 164 Gaps:31 74.59 181 41.48 5e-34 cd03766 Gn_AT_II_novel Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to members of the Ntn (N-terminal nucleophile) hydrolase superfamily and is found at the N-terminus of enzymes such as glucosamine-fructose 6-phosphate synthase (GLMS or GFAT) glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) asparagine synthetase B (AsnB) beta lactam synthetase (beta-LS) and glutamate synthase (GltS). GLMS catalyzes the formation of glucosamine 6-phosphate from fructose 6-phosphate and glutamine in amino sugar synthesis. GPATase catalyzes the first step in purine biosynthesis an amide transfer from glutamine to PRPP resulting in phosphoribosylamine pyrophosphate and glutamate. Asparagine synthetase B synthesizes asparagine from aspartate and glutamine. Beta-LS catalyzes the formation of the beta-lactam ring in the beta-lactamase inhibitor clavulanic acid. GltS synthesizes L-glutamate from 2-oxoglutarate and L-glutamine. These enzymes are generally dimers but GPATase also exists as a homotetramer..
rpsblast_cdd gnl|CDD|30178 386 657 + 272 Gaps:78 99.63 269 27.24 5e-24 cd01991 Asn_Synthase_B_C The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the assembly of asparagine from aspartate Mg(2+)ATP and glutamine. The three-dimensional architecture of the N-terminal domain of asparagine synthetase B is similar to that observed for glutamine phosphoribosylpyrophosphate amidotransferase while the molecular motif of the C-domain is reminiscent to that observed for GMP synthetase ..
rpsblast_cdd gnl|CDD|30716 131 669 + 539 Gaps:75 63.28 542 28.28 7e-23 COG0367 AsnB Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism].
rpsblast_cdd gnl|CDD|201418 374 651 + 278 Gaps:95 97.95 195 32.98 2e-22 pfam00733 Asn_synthase Asparagine synthase. This family is always found associated with pfam00310. Members of this family catalyze the conversion of aspartate to asparagine.
rpsblast_cdd gnl|CDD|188154 126 639 + 514 Gaps:144 87.55 466 24.26 2e-18 TIGR01536 asn_synth_AEB asparagine synthase (glutamine-hydrolyzing). This model describes the glutamine-hydrolysing asparagine synthase. A poorly conserved C-terminal extension was removed from the model. Bacterial members of the family tend to have a long poorly conserved insert lacking from archaeal and eukaryotic sequences. Multiple isozymes have been demonstrated such as in Bacillus subtilis. Long-branch members of the phylogenetic tree (which typically were also second or third candidate members from their genomes) were removed from the seed alignment and score below trusted cutoff.
rpsblast_cdd gnl|CDD|48475 141 253 + 113 Gaps:27 50.00 220 26.36 1e-08 cd00352 Gn_AT_II Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to members of the Ntn (N-terminal nucleophile) hydrolase superfamily and is found at the N-terminus of enzymes such as glucosamine-fructose 6-phosphate synthase (GLMS or GFAT) glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) asparagine synthetase B (AsnB) beta lactam synthetase (beta-LS) and glutamate synthase (GltS). GLMS catalyzes the formation of glucosamine 6-phosphate from fructose 6-phosphate and glutamine in amino sugar synthesis. GPATase catalyzes the first step in purine biosynthesis an amide transfer from glutamine to PRPP resulting in phosphoribosylamine pyrophosphate and glutamate. Asparagine synthetase B synthesizes asparagine from aspartate and glutamine. Beta-LS catalyzes the formation of the beta-lactam ring in the beta-lactamase inhibitor clavulanic acid. GltS synthesizes L-glutamate from 2-oxoglutarate and L-glutamine. These enzymes are generally dimers but GPATase also exists as a homotetramer..
rpsblast_kog gnl|CDD|35793 124 673 + 550 Gaps:99 89.81 520 35.97 3e-85 KOG0573 KOG0573 KOG0573 Asparagine synthase [Amino acid transport and metabolism].

13 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 123 253 131 SSF56235 none none IPR029055
SUPERFAMILY 44 60 17 SSF56235 none none IPR029055
PANTHER 2 53 52 PTHR11772 none none none
PANTHER 2 53 52 PTHR11772:SF3 none none none
SUPERFAMILY 538 679 142 SSF52402 none none none
SUPERFAMILY 402 495 94 SSF52402 none none none
Pfam 141 253 113 PF13537 none Glutamine amidotransferase domain IPR000583
Gene3D 42 86 45 G3DSA:3.60.20.10 none none IPR029055
Gene3D 124 254 131 G3DSA:3.60.20.10 none none IPR029055
Gene3D 361 680 320 G3DSA:3.40.50.620 none none IPR014729
PANTHER 91 679 589 PTHR11772:SF3 none none none
PANTHER 91 679 589 PTHR11772 none none none
Pfam 401 651 251 PF00733 none Asparagine synthase IPR001962

0 Localization

0 Qtllist

0 Targeting