Protein : Qrob_P0709510.2 Q. robur

Protein Identifier  ? Qrob_P0709510.2 Organism . Name  Quercus robur
Score  88.2 Score Type  egn
Protein Description  (M=3) 2.1.1.226 - 23S rRNA (cytidine(1920)-2'-O)-methyltransferase. Code Enzyme  EC:2.1.1.227, EC:2.1.1.226
Gene Prediction Quality  validated Protein length 

Sequence

Length: 278  
Kegg Orthology  K06442

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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003723 RNA binding Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
GO:0008168 methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0032259 methylation The process in which a methyl group is covalently attached to a molecule.

20 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1628240 2 274 + 273 none 87.50 312 87.55 2e-174 Hemolysin A putative
blastp_kegg lcl|tcc:TCM_002613 7 271 + 265 none 91.38 290 89.81 8e-170 Bacterial hemolysin-related isoform 1
blastp_kegg lcl|vvi:100254915 6 273 + 268 none 89.33 300 84.70 3e-164 uncharacterized LOC100254915
blastp_kegg lcl|fve:101291775 6 277 + 272 none 86.08 316 81.25 6e-163 putative rRNA methyltransferase YqxC-like
blastp_kegg lcl|pxb:103934372 5 277 + 273 Gaps:3 82.07 329 83.70 1e-162 uncharacterized LOC103934372
blastp_kegg lcl|pxb:103934359 5 277 + 273 Gaps:3 82.07 329 83.70 1e-162 uncharacterized LOC103934359
blastp_kegg lcl|cit:102609926 1 276 + 276 Gaps:3 88.29 316 81.72 3e-162 uncharacterized LOC102609926
blastp_kegg lcl|mdm:103445327 2 277 + 276 Gaps:3 82.98 329 81.32 7e-161 uncharacterized LOC103445327
blastp_kegg lcl|pvu:PHAVU_010G036400g 3 270 + 268 none 85.62 313 82.46 2e-159 hypothetical protein
blastp_kegg lcl|pmum:103334673 2 277 + 276 Gaps:7 84.59 318 82.90 2e-159 uncharacterized LOC103334673
blastp_pdb 3opn_A 80 268 + 189 Gaps:3 82.76 232 45.31 6e-52 mol:protein length:232 putative hemolysin
blastp_pdb 3hp7_A 32 271 + 240 Gaps:11 84.19 291 36.73 3e-47 mol:protein length:291 Hemolysin putative
blastp_uniprot_sprot sp|P19672|YQXC_BACSU 31 273 + 243 Gaps:9 87.54 281 41.06 2e-53 Putative rRNA methyltransferase YqxC OS Bacillus subtilis (strain 168) GN yqxC PE 3 SV 3
blastp_uniprot_sprot sp|Q50760|TLYA_MYCTU 31 274 + 244 Gaps:3 92.16 268 38.87 2e-50 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA OS Mycobacterium tuberculosis GN tlyA PE 1 SV 2
blastp_uniprot_sprot sp|Q06803|HLYA_BRAHO 34 268 + 235 Gaps:10 98.75 240 40.51 3e-49 Hemolysin A OS Brachyspira hyodysenteriae GN tlyA PE 2 SV 1
blastp_uniprot_sprot sp|Q8DEV0|RLUD_VIBVU 33 86 + 54 none 16.62 325 42.59 5e-06 Ribosomal large subunit pseudouridine synthase D OS Vibrio vulnificus (strain CMCP6) GN rluD PE 3 SV 1
rpsblast_cdd gnl|CDD|31382 31 273 + 243 Gaps:2 100.00 245 47.76 3e-67 COG1189 COG1189 Predicted rRNA methylase [Translation ribosomal structure and biogenesis].
rpsblast_cdd gnl|CDD|129570 34 263 + 230 Gaps:6 100.00 228 42.54 8e-51 TIGR00478 tly hemolysin TlyA family protein. Hemolysins are exotoxins that attack blood cell membranes and cause cell rupture often by forming a pore in the membrane. At least two members of this protein family have been characterized indirectly as pore-forming hemolysins one from the spirochete Serpula (Treponema) hyodysenteriae and one from Mycobacterium tuberculosis. However homology domains in this protein suggest methyltransferase activity (pfam01728) and RNA-binding activity (pfam01479).
rpsblast_cdd gnl|CDD|201939 89 270 + 182 Gaps:27 100.00 177 31.07 5e-23 pfam01728 FtsJ FtsJ-like methyltransferase. This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesised that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
rpsblast_cdd gnl|CDD|183020 34 86 + 53 none 16.31 325 47.17 5e-09 PRK11180 rluD 23S rRNA pseudouridine synthase D Provisional.

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 32 131 100 G3DSA:3.10.290.10 none none IPR002942
TIGRFAM 34 263 230 TIGR00478 none tly: TlyA family rRNA methyltransferase/putative hemolysin IPR004538
Pfam 33 80 48 PF01479 none S4 domain IPR002942
PIRSF 28 277 250 PIRSF005578 none none IPR004538
ProSiteProfiles 33 93 61 PS50889 none S4 RNA-binding domain profile. IPR002942
PANTHER 25 277 253 PTHR32319 none none none
SUPERFAMILY 89 269 181 SSF53335 none none IPR029063
Phobius 1 172 172 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 173 193 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 25 277 253 PTHR32319:SF0 none none none
Pfam 89 268 180 PF01728 none FtsJ-like methyltransferase IPR002877
Phobius 194 277 84 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 32 85 54 SSF55174 none none none
SMART 33 98 66 SM00363 none S4 RNA-binding domain IPR002942

1 Localization

Analysis Start End Length
TMHMM 173 195 22

0 Qtllist

0 Targeting