Protein : Qrob_P0632630.2 Q. robur
Protein Identifier  ? Qrob_P0632630.2 Organism . Name  Quercus robur
Score  54.9 Score Type  egn
Protein Description  (M=9) K18999 - RNA polymerase II C-terminal domain phosphatase-like 3/4 [EC:3.1.3.16] Code Enzyme  EC:3.1.3.16
Gene Prediction Quality  validated Protein length 

Sequence

Length: 375  
Kegg Orthology  K18999
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005634 nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
GO:0004721 phosphoprotein phosphatase activity Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.

29 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|sly:101265041 30 370 + 341 Gaps:19 75.00 472 43.50 2e-83 RNA polymerase II C-terminal domain phosphatase-like 4-like
blastp_kegg lcl|sly:101264737 2 370 + 369 Gaps:28 75.20 512 42.34 5e-83 RNA polymerase II C-terminal domain phosphatase-like 4-like
blastp_kegg lcl|sot:102591519 30 370 + 341 Gaps:19 74.06 478 42.66 1e-79 RNA polymerase II C-terminal domain phosphatase-like 4-like
blastp_kegg lcl|csv:101207983 28 371 + 344 Gaps:20 78.76 452 42.98 2e-78 RNA polymerase II C-terminal domain phosphatase-like 4-like
blastp_kegg lcl|cmo:103498688 28 371 + 344 Gaps:23 78.98 452 43.14 2e-77 RNA polymerase II C-terminal domain phosphatase-like 4
blastp_kegg lcl|rcu:RCOM_1628950 28 370 + 343 Gaps:20 74.27 478 42.25 8e-77 RNA polymerase II ctd phosphatase putative (EC:3.1.3.16)
blastp_kegg lcl|pper:PRUPE_ppa005647mg 21 355 + 335 Gaps:17 76.61 449 44.19 3e-75 hypothetical protein
blastp_kegg lcl|fve:101311893 24 370 + 347 Gaps:20 77.37 464 42.90 2e-74 RNA polymerase II C-terminal domain phosphatase-like 4-like
blastp_kegg lcl|tcc:TCM_039510 28 370 + 343 Gaps:20 75.69 469 42.25 3e-74 RNA polymerase II ctd phosphatase putative isoform 1
blastp_kegg lcl|pmum:103341256 21 355 + 335 Gaps:19 76.61 449 44.19 6e-74 RNA polymerase II C-terminal domain phosphatase-like 4
blastp_pdb 3ef0_A 65 368 + 304 Gaps:65 98.12 372 27.40 4e-20 mol:protein length:372 RNA polymerase II subunit A C-terminal domain
blastp_pdb 3ef1_A 65 219 + 155 Gaps:15 38.01 442 31.55 1e-13 mol:protein length:442 RNA polymerase II subunit A C-terminal domain
blastp_uniprot_sprot sp|Q00IB6|CPL4_ARATH 28 371 + 344 Gaps:24 81.36 440 42.18 7e-73 RNA polymerase II C-terminal domain phosphatase-like 4 OS Arabidopsis thaliana GN CPL4 PE 1 SV 1
blastp_uniprot_sprot sp|Q8LL04|CPL3_ARATH 66 356 + 291 Gaps:25 24.82 1241 35.71 4e-39 RNA polymerase II C-terminal domain phosphatase-like 3 OS Arabidopsis thaliana GN CPL3 PE 1 SV 2
blastp_uniprot_sprot sp|Q9Y5B0|CTDP1_HUMAN 66 221 + 156 Gaps:19 15.92 961 40.52 7e-23 RNA polymerase II subunit A C-terminal domain phosphatase OS Homo sapiens GN CTDP1 PE 1 SV 3
blastp_uniprot_sprot sp|Q7TSG2|CTDP1_MOUSE 66 219 + 154 Gaps:19 15.73 960 40.40 7e-22 RNA polymerase II subunit A C-terminal domain phosphatase OS Mus musculus GN Ctdp1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8SV03|FCP1_ENCCU 30 220 + 191 Gaps:16 45.01 411 34.59 2e-20 RNA polymerase II subunit A C-terminal domain phosphatase OS Encephalitozoon cuniculi (strain GB-M1) GN FCP1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9P376|FCP1_SCHPO 21 219 + 199 Gaps:38 30.29 723 31.05 2e-14 RNA polymerase II subunit A C-terminal domain phosphatase OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN fcp1 PE 1 SV 1
blastp_uniprot_sprot sp|Q03254|FCP1_YEAST 29 219 + 191 Gaps:37 30.60 732 29.02 1e-13 RNA polymerase II subunit A C-terminal domain phosphatase OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN FCP1 PE 1 SV 1
blastp_uniprot_sprot sp|Q5XIK8|CTSL2_RAT 78 217 + 140 Gaps:11 29.03 465 33.33 9e-09 CTD small phosphatase-like protein 2 OS Rattus norvegicus GN Ctdspl2 PE 2 SV 1
blastp_uniprot_sprot sp|Q8BG15|CTSL2_MOUSE 78 217 + 140 Gaps:11 29.03 465 33.33 1e-08 CTD small phosphatase-like protein 2 OS Mus musculus GN Ctdspl2 PE 2 SV 1
blastp_uniprot_sprot sp|Q05D32|CTSL2_HUMAN 78 217 + 140 Gaps:11 28.97 466 33.33 1e-08 CTD small phosphatase-like protein 2 OS Homo sapiens GN CTDSPL2 PE 1 SV 2
rpsblast_cdd gnl|CDD|131304 70 219 + 150 Gaps:6 100.00 156 39.10 1e-42 TIGR02250 FCP1_euk FCP1-like phosphatase phosphatase domain. This model represents the phosphatase domain of the humanRNA polymerase II subunit A C-terminal domain phosphatase (FCP1 ) and closely related phosphatases from eukaryotes including plants fungi and slime mold. This domain is a member of the haloacid dehalogenase (HAD) superfamily by virtue of a conserved set of three catalytic motifs and a conserved fold as predicted by PSIPRED. The third motif in this family is distinctive (hhhhDDppphW). This domain is classified as a "Class III" HAD since there is no large "cap" domain found between motifs 1 and 2 or motifs 2 and 3.This domain is related to domains found in the human NLI interacting factor-like phosphatases and together both are detected by the Pfam model pfam03031.
rpsblast_cdd gnl|CDD|197796 74 219 + 146 Gaps:8 97.30 148 36.81 2e-34 smart00577 CPDc catalytic domain of ctd-like phosphatases.
rpsblast_cdd gnl|CDD|202514 76 217 + 142 Gaps:14 83.66 153 30.47 2e-23 pfam03031 NIF NLI interacting factor-like phosphatase. This family contains a number of NLI interacting factor isoforms and also an N-terminal regions of RNA polymerase II CTC phosphatase and FCP1 serine phosphatase. This region has been identified as the minimal phosphatase domain.
rpsblast_cdd gnl|CDD|162785 75 218 + 144 Gaps:12 86.42 162 30.00 1e-15 TIGR02251 HIF-SF_euk Dullard-like phosphatase domain. This model represents the putative phosphatase domain of a family of eukaryotic proteins including "Dullard" and the NLI interacting factor (NIF)-like phosphatases. This domain is a member of the haloacid dehalogenase (HAD) superfamily by virtue of a conserved set of three catalytic motifs and a conserved fold as predicted by PSIPRED. The third motif in this family is distinctive (hhhhDNxPxxa) and aparrently lacking the last aspartate. This domain is classified as a "Class III" HAD since there is no large "cap" domain found between motifs 1 and 2 or motifs 2 and 3. This domain is related to domains found in FCP1-like phosphatases (TIGR02250) and together both are detected by the Pfam model pfam03031.
rpsblast_cdd gnl|CDD|34789 68 270 + 203 Gaps:11 51.28 390 29.50 4e-08 COG5190 FCP1 TFIIF-interacting CTD phosphatases including NLI-interacting factor [Transcription].
rpsblast_kog gnl|CDD|35544 29 369 + 341 Gaps:25 54.65 635 33.72 6e-39 KOG0323 KOG0323 KOG0323 TFIIF-interacting CTD phosphatases including NLI-interacting factor [Transcription].
rpsblast_kog gnl|CDD|36818 65 217 + 153 Gaps:9 57.25 262 25.33 1e-11 KOG1605 KOG1605 KOG1605 TFIIF-interacting CTD phosphatase including NLI-interacting factor (involved in RNA polymerase II regulation) [Transcription].

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSiteProfiles 71 236 166 PS50969 none FCP1 homology domain profile. IPR004274
Gene3D 66 252 187 G3DSA:3.40.50.1000 none none IPR023214
SMART 74 223 150 SM00577 none catalytic domain of ctd-like phosphatases IPR004274
Pfam 77 224 148 PF03031 none NLI interacting factor-like phosphatase IPR004274
ProSiteProfiles 277 370 94 PS50172 none BRCT domain profile. IPR001357
PANTHER 71 371 301 PTHR23081 none none none
TIGRFAM 70 219 150 TIGR02250 none FCP1_euk: FCP1-like phosphatase, phosphatase domain IPR011947
Gene3D 280 371 92 G3DSA:3.40.50.10190 none none IPR001357
SUPERFAMILY 34 56 23 SSF52113 none none IPR001357
SUPERFAMILY 281 370 90 SSF52113 none none IPR001357
SUPERFAMILY 69 222 154 SSF56784 none none IPR023214

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2004_QTL5_peak_Bud_burst_A4 Qrob_Chr10 10 s_1C8OKQ_688 v_12844_707 25,6 13,9 39,9 lod 2,7 6,1
Bourran2_2002_QTL13_peak_Bud_burst_3P Qrob_Chr10 10 s_1B1AG7_637 s_1A3A1N_709 19,44 0 49,44 lod 3 5,6
Bourran2_2002_QTL15_peak_Bud_burst_A4 Qrob_Chr10 10 v_7579_71 s_1ATZMJ_189 23,94 0 43,64 lod 3,7 5,4
Bourran2_2014_vSeqBC_A4 Qrob_Chr10 10 s_1BAM4E_1326 s_1C0HD0_1012 36,88 7,71 46,03 lod 2,6164 7,3
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
PM_1999_QTL16_peak_Bud_burst_3P Qrob_Chr10 10 s_1B6YNI_505 s_1A1ZO_1322 7,48 0 31,48 lod 4 7,1

0 Targeting