Protein : Qrob_P0619080.2 Q. robur
Protein Identifier  ? Qrob_P0619080.2 Organism . Name  Quercus robur
Score  45.0 Score Type  egn
Protein Description  (M=2) K04499 - RuvB-like protein 1 (pontin 52) Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 337  
Kegg Orthology  K04499
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003678 DNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
GO:0043141 ATP-dependent 5'-3' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pxb:103966378 1 320 + 320 Gaps:46 79.91 458 77.87 0.0 ruvB-like protein 1
blastp_kegg lcl|mdm:103441877 1 320 + 320 Gaps:46 79.91 458 77.60 0.0 ruvB-like protein 1
blastp_kegg lcl|mdm:103452023 1 320 + 320 Gaps:46 79.91 458 77.32 0.0 ruvB-like protein 1
blastp_kegg lcl|pxb:103963840 1 320 + 320 Gaps:46 79.91 458 76.78 0.0 ruvB-like protein 1
blastp_kegg lcl|pmum:103329057 1 325 + 325 Gaps:48 80.57 458 77.24 0.0 ruvB-like protein 1
blastp_kegg lcl|pper:PRUPE_ppa005491mg 1 315 + 315 Gaps:46 81.49 443 78.12 0.0 hypothetical protein
blastp_kegg lcl|gmx:102659805 1 320 + 320 Gaps:46 79.91 458 77.05 0.0 ruvB-like protein 1-like
blastp_kegg lcl|cmo:103486970 1 320 + 320 Gaps:46 79.91 458 76.23 0.0 ruvB-like protein 1
blastp_kegg lcl|csv:101210899 1 320 + 320 Gaps:46 79.91 458 76.23 0.0 ruvB-like 1-like
blastp_kegg lcl|fve:101309228 1 320 + 320 Gaps:46 79.91 458 76.50 0.0 ruvB-like 1-like
blastp_pdb 2c9o_C 4 323 + 320 Gaps:47 80.48 456 61.85 2e-153 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2c9o_B 4 323 + 320 Gaps:47 80.48 456 61.85 2e-153 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2c9o_A 4 323 + 320 Gaps:47 80.48 456 61.85 2e-153 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2xsz_C 5 323 + 319 Gaps:1 60.22 367 68.78 3e-56 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_B 5 323 + 319 Gaps:1 60.22 367 68.78 3e-56 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_A 5 323 + 319 Gaps:1 60.22 367 68.78 3e-56 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_F 5 296 + 292 Gaps:64 60.32 378 46.05 3e-47 mol:protein length:378 RUVB-LIKE 2
blastp_pdb 2xsz_E 5 296 + 292 Gaps:64 60.32 378 46.05 3e-47 mol:protein length:378 RUVB-LIKE 2
blastp_pdb 2xsz_D 5 296 + 292 Gaps:64 60.32 378 46.05 3e-47 mol:protein length:378 RUVB-LIKE 2
blastp_uniprot_sprot sp|Q9FMR9|RIN1_ARATH 1 321 + 321 Gaps:46 80.13 458 73.84 0.0 RuvB-like protein 1 OS Arabidopsis thaliana GN RIN1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9DE26|RUVB1_XENLA 4 296 + 293 Gaps:46 74.34 456 66.08 2e-154 RuvB-like 1 OS Xenopus laevis GN ruvbl1 PE 2 SV 1
blastp_uniprot_sprot sp|P60123|RUVB1_RAT 4 323 + 320 Gaps:47 80.48 456 62.13 4e-153 RuvB-like 1 OS Rattus norvegicus GN Ruvbl1 PE 1 SV 1
blastp_uniprot_sprot sp|P60122|RUVB1_MOUSE 4 323 + 320 Gaps:47 80.48 456 62.13 4e-153 RuvB-like 1 OS Mus musculus GN Ruvbl1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9Y265|RUVB1_HUMAN 4 323 + 320 Gaps:47 80.48 456 61.85 7e-153 RuvB-like 1 OS Homo sapiens GN RUVBL1 PE 1 SV 1
blastp_uniprot_sprot sp|Q0IFL2|RUVB1_AEDAE 4 315 + 312 Gaps:47 78.73 456 61.84 8e-153 RuvB-like helicase 1 OS Aedes aegypti GN pont PE 3 SV 1
blastp_uniprot_sprot sp|Q8AWW7|RUVB1_DANRE 4 296 + 293 Gaps:46 74.34 456 65.19 9e-153 RuvB-like 1 OS Danio rerio GN ruvbl1 PE 2 SV 1
blastp_uniprot_sprot sp|Q29AK9|RUVB1_DROPS 4 296 + 293 Gaps:46 74.34 456 64.31 8e-152 RuvB-like helicase 1 OS Drosophila pseudoobscura pseudoobscura GN pont PE 3 SV 1
blastp_uniprot_sprot sp|Q4WPW8|RUVB1_ASPFU 4 296 + 293 Gaps:46 74.02 458 64.60 2e-151 RuvB-like helicase 1 OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN rvb1 PE 3 SV 1
blastp_uniprot_sprot sp|Q9VH07|RUVB1_DROME 4 296 + 293 Gaps:46 74.34 456 64.31 3e-151 RuvB-like helicase 1 OS Drosophila melanogaster GN pont PE 1 SV 1
rpsblast_cdd gnl|CDD|147949 17 296 + 280 Gaps:53 80.76 395 54.86 1e-118 pfam06068 TIP49 TIP49 C-terminus. This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish the liebeskummer (lik) mutation causes development of hyperplastic embryonic hearts. lik encodes Reptin a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin a DNA-stimulated ATPase that is often part of complexes with Reptin are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein and two related proteins are encoded by individual genes tip49a and b. Although the function of this gene family has not been elucidated they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 296 296 PTHR11093 none none IPR027238
Gene3D 228 291 64 G3DSA:3.40.50.300 none none IPR027417
Gene3D 41 101 61 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 41 302 262 SSF52540 none none IPR027417
SMART 65 306 242 SM00382 none ATPases associated with a variety of cellular activities IPR003593
Pfam 93 315 223 PF06068 none TIP49 C-terminus IPR010339

0 Localization

10 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2004_QTL1_peak_Bud_burst_A4 Qrob_Chr01 1 s_1AMVCC_444 s_1BE1VC_321 4 0 31 lod 3,2 7,4
Bourran2_2003_QTL8_peak_Bud_burst_A4 Qrob_Chr01 1 s_1AH7I_610 s_1BE1VC_321 4,6 0 28 lod 3,5 7,4
Bourran2_2007_QTL6_peak_Bud_burst_3P Qrob_Chr01 1 s_1BE1VC_321 s_1A5JRZ_890 5 0 25 lod 2,4 6
Bourran2_2014_nEpiBC_3P Qrob_Chr01 1 v_1588_550 s_1AZJRA_1600 30,48 9,48 43,98 lod 2,3642 6,3
Bourran2_2014_nLBD*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 34,91 16,12 53,62 lod 2,4961 5,2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC*_A4 Qrob_Chr08 8 v_12498_318 v_12364_308 35,77 14,11 55,31 lod 2,9413 6,2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Bourran2_2014_nSeqBC*_A4 Qrob_Chr01 1 s_1CFE4C_2114 s_1BDNCB_819 15,25 2 28,5 lod 2,9903 8,3

0 Targeting