Protein : Qrob_P0584100.2 Q. robur
Protein Identifier  ? Qrob_P0584100.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K03122 - transcription initiation factor TFIIA large subunit Gene Prediction Quality  validated
Protein length 

Sequence

Length: 160  
Kegg Orthology  K03122
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

2 GO Terms

Identifier Name Description
GO:0006367 transcription initiation from RNA polymerase II promoter Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
GO:0005672 transcription factor TFIIA complex A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).

13 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pvu:PHAVU_005G159000g 1 127 + 127 Gaps:71 42.60 385 47.56 5e-30 hypothetical protein
blastp_kegg lcl|tcc:TCM_041779 1 130 + 130 Gaps:75 43.51 393 45.03 3e-26 Transcription initiation factor IIA subunit 1
blastp_kegg lcl|csv:101206619 3 127 + 125 Gaps:65 43.28 402 41.38 5e-26 transcription initiation factor IIA large subunit-like
blastp_kegg lcl|cmo:103502057 3 127 + 125 Gaps:65 43.39 401 41.38 1e-25 transcription initiation factor IIA subunit 1
blastp_kegg lcl|pmum:103322014 3 127 + 125 Gaps:71 43.52 386 43.45 5e-25 transcription initiation factor IIA large subunit-like
blastp_kegg lcl|pper:PRUPE_ppa006992mg 3 127 + 125 Gaps:71 43.52 386 43.45 5e-25 hypothetical protein
blastp_kegg lcl|fve:101296939 5 127 + 123 Gaps:46 43.77 377 43.03 1e-22 transcription initiation factor IIA large subunit-like
blastp_kegg lcl|pxb:103964701 3 127 + 125 Gaps:75 43.93 387 42.35 2e-22 transcription initiation factor IIA large subunit
blastp_kegg lcl|cam:101500579 42 127 + 86 Gaps:16 17.99 389 74.29 2e-22 transcription initiation factor IIA large subunit-like
blastp_kegg lcl|mdm:103447502 3 127 + 125 Gaps:75 43.93 387 42.35 2e-22 transcription initiation factor IIA large subunit
rpsblast_cdd gnl|CDD|202557 9 114 + 106 Gaps:35 41.87 332 22.30 2e-08 pfam03153 TFIIA Transcription factor IIA alpha/beta subunit. Transcription initiation factor IIA (TFIIA) is a heterotrimer the three subunits being known as alpha beta and gamma in order of molecular weight. The N and C-terminal domains of the gamma subunit are represented in pfam02268 and pfam02751 respectively. This family represents the precursor that yields both the alpha and beta subunits. The TFIIA heterotrimer is an essential general transcription initiation factor for the expression of genes transcribed by RNA polymerase II. Together with TFIID TFIIA binds to the promoter region this is the first step in the formation of a pre-initiation complex (PIC). Binding of the rest of the transcription machinery follows this step. After initiation the PIC does not completely dissociate from the promoter. Some components including TFIIA remain attached and re-initiate a subsequent round of transcription.
rpsblast_cdd gnl|CDD|199899 6 40 + 35 Gaps:1 33.33 102 55.88 6e-08 cd07976 TFIIA_alpha_beta_like Precursor of TFIIA alpha and beta subunits and similar proteins. Transcription factor II A (TFIIA) is one of the general transcription factors for RNA polymerase II. TFIIA increases the affinity of TATA-binding protein (TBP) for DNA in order to assemble the initiation complex. TFIIA also functions as an activator during development and differentiation and is involved in transcription from TATA-less promoters. TFIIA is composed of more than one subunit in various organisms. Mammalian TFIIA large subunits (TFIIA alpha and beta) and the smaller subunit (TFIIA gamma) form a heterotrimer. TFIIA alpha and beta are encoded by a single gene (TFIIA_alpha_beta) its protein product is post-translationally processed and cleaved. TOA1 and TOA2 are the two subunits of Yeast TFIIA which correspond to Mammalian TFIIA_alpha_beta and TFIIA gamma respectively. TOA1 and TOA2 form a heterodimeric protein complex. TFIIA_alpha_beta alone is sufficient for transcription in early embryogenesis but the cleaved forms TFIIA alpha and TFIIA beta represent the vast majority of TFIIA in most differentiated cells. The exact functional differences between cleaved and uncleaved forms are not yet clear. This model also contains paralogs of the canonical TFIIA_alpha_beta such as the human ALF which may be involved in gametogenesis and early embryogenesis (and is also subject to proteolytic cleavage).
rpsblast_kog gnl|CDD|37863 1 143 + 143 Gaps:33 50.00 348 20.11 1e-07 KOG2652 KOG2652 KOG2652 RNA polymerase II transcription initiation factor TFIIA large chain [Transcription].

5 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 1 40 40 PTHR12694 none none IPR004855
PANTHER 1 40 40 PTHR12694:SF8 none none none
SUPERFAMILY 5 41 37 SSF47396 none none IPR009083
Pfam 9 41 33 PF03153 none Transcription factor IIA, alpha/beta subunit IPR004855
Gene3D 3 40 38 G3DSA:1.10.287.100 none none IPR013028

0 Localization

0 Qtllist

0 Targeting