Protein : Qrob_P0565350.2 Q. robur
Protein Identifier  ? Qrob_P0565350.2 Organism . Name  Quercus robur
Score  97.0 Score Type  egn
Protein Description  (M=1) K04718 - sphingosine kinase [EC:2.7.1.91] Code Enzyme  EC:2.7.1.91
Gene Prediction Quality  validated Protein length 

Sequence

Length: 493  
Kegg Orthology  K04718
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0 Synonyms

1 GO Terms

Identifier Name Description
GO:0016301 kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103324637 1 492 + 492 Gaps:3 100.00 493 76.88 0.0 sphingosine kinase 1-like
blastp_kegg lcl|pper:PRUPE_ppa004781mg 1 492 + 492 Gaps:5 100.00 491 77.60 0.0 hypothetical protein
blastp_kegg lcl|vvi:100248229 1 492 + 492 Gaps:7 100.00 489 74.85 0.0 sphingosine kinase B-like
blastp_kegg lcl|pxb:103964944 4 492 + 489 Gaps:3 98.99 495 74.29 0.0 sphingosine kinase 1
blastp_kegg lcl|rcu:RCOM_1095760 6 492 + 487 Gaps:9 99.79 479 73.85 0.0 Sphingosine kinase putative (EC:2.7.1.138)
blastp_kegg lcl|mdm:103427837 4 492 + 489 Gaps:3 98.99 495 73.88 0.0 sphingosine kinase 1-like
blastp_kegg lcl|tcc:TCM_029978 3 483 + 481 Gaps:6 97.74 486 73.47 0.0 Sphingosine kinase 1 isoform 1
blastp_kegg lcl|fve:101311446 1 491 + 491 Gaps:9 98.59 497 72.45 0.0 sphingosine kinase B-like
blastp_kegg lcl|pop:POPTR_0011s04330g 12 492 + 481 Gaps:6 97.77 494 72.46 0.0 POPTRDRAFT_568293 diacylglycerol kinase family protein
blastp_kegg lcl|cam:101499291 9 492 + 484 Gaps:1 98.77 489 70.19 0.0 sphingosine kinase A-like
blastp_uniprot_sprot sp|Q8L7L1|SPHK1_ARATH 3 491 + 489 Gaps:16 99.18 485 67.98 0.0 Sphingosine kinase 1 OS Arabidopsis thaliana GN SPHK1 PE 1 SV 1
blastp_uniprot_sprot sp|F2Y4A3|SPHK2_ARATH 1 491 + 491 Gaps:14 99.58 481 66.18 0.0 Sphingosine kinase 2 OS Arabidopsis thaliana GN SPHK2 PE 1 SV 1
blastp_uniprot_sprot sp|Q8TCT0|CERK1_HUMAN 98 490 + 393 Gaps:35 76.72 537 29.37 2e-44 Ceramide kinase OS Homo sapiens GN CERK PE 1 SV 1
blastp_uniprot_sprot sp|Q9NYA1|SPHK1_HUMAN 111 457 + 347 Gaps:34 87.24 384 35.22 4e-44 Sphingosine kinase 1 OS Homo sapiens GN SPHK1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8K4Q7|CERK1_MOUSE 98 490 + 393 Gaps:39 77.59 531 31.31 7e-43 Ceramide kinase OS Mus musculus GN Cerk PE 2 SV 2
blastp_uniprot_sprot sp|Q86KF9|SPHKA_DICDI 84 466 + 383 Gaps:19 53.04 624 38.67 7e-42 Sphingosine kinase A OS Dictyostelium discoideum GN sgkA PE 2 SV 2
blastp_uniprot_sprot sp|Q9JIA7|SPHK2_MOUSE 111 490 + 380 Gaps:32 51.86 617 39.69 1e-41 Sphingosine kinase 2 OS Mus musculus GN Sphk2 PE 1 SV 2
blastp_uniprot_sprot sp|Q8CI15|SPHK1_MOUSE 111 457 + 347 Gaps:37 87.43 382 33.53 2e-41 Sphingosine kinase 1 OS Mus musculus GN Sphk1 PE 1 SV 1
blastp_uniprot_sprot sp|Q91V26|SPHK1_RAT 111 457 + 347 Gaps:33 87.21 383 33.53 6e-41 Sphingosine kinase 1 OS Rattus norvegicus GN Sphk1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9NRA0|SPHK2_HUMAN 121 309 + 189 Gaps:6 29.82 654 41.03 4e-39 Sphingosine kinase 2 OS Homo sapiens GN SPHK2 PE 1 SV 2
rpsblast_cdd gnl|CDD|166599 1 492 + 492 Gaps:13 99.58 481 78.29 0.0 PLN02958 PLN02958 diacylglycerol kinase/D-erythro-sphingosine kinase.
rpsblast_cdd gnl|CDD|31785 115 457 + 343 Gaps:71 91.03 301 30.29 2e-30 COG1597 LCB5 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].
rpsblast_cdd gnl|CDD|201440 116 247 + 132 Gaps:11 96.85 127 35.77 4e-25 pfam00781 DAGK_cat Diacylglycerol kinase catalytic domain. Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologues. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs revealing a novel metal-binding site. The residues of this site are conserved across the family.
rpsblast_cdd gnl|CDD|161732 115 457 + 343 Gaps:77 93.52 293 27.74 1e-14 TIGR00147 TIGR00147 lipid kinase YegS/Rv2252/BmrU family. The E. coli member of this family YegS has been purified and shown to have phosphatidylglycerol kinase activity. The member from M. tuberculosis Rv2252 has diacylglycerol kinase activity. BmrU from B. subtilis is in an operon with multidrug efflux transporter Bmr but is uncharacterized.
rpsblast_cdd gnl|CDD|177854 108 490 + 383 Gaps:66 60.57 601 30.77 6e-14 PLN02204 PLN02204 diacylglycerol kinase.
rpsblast_cdd gnl|CDD|197486 118 220 + 103 Gaps:7 77.42 124 28.12 4e-11 smart00046 DAGKc Diacylglycerol kinase catalytic domain (presumed). Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. DAG can be produced from the hydrolysis of phosphatidylinositol 4 5-bisphosphate (PIP2) by a phosphoinositide-specific phospholipase C and by the degradation of phosphatidylcholine (PC) by a phospholipase C or the concerted actions of phospholipase D and phosphatidate phosphohydrolase. This domain is presumed to be the catalytic domain. Bacterial homologues areknown.
rpsblast_cdd gnl|CDD|183982 115 247 + 133 Gaps:12 40.46 304 31.71 4e-08 PRK13337 PRK13337 putative lipid kinase Reviewed.
rpsblast_cdd gnl|CDD|183858 115 301 + 187 Gaps:28 58.64 295 24.28 8e-07 PRK13059 PRK13059 putative lipid kinase Reviewed.
rpsblast_kog gnl|CDD|36332 6 491 + 486 Gaps:78 81.52 579 34.96 1e-87 KOG1116 KOG1116 KOG1116 Sphingosine kinase involved in sphingolipid metabolism [Lipid transport and metabolism Signal transduction mechanisms].
rpsblast_kog gnl|CDD|36331 98 457 + 360 Gaps:52 67.44 516 30.17 2e-37 KOG1115 KOG1115 KOG1115 Ceramide kinase [Lipid transport and metabolism Signal transduction mechanisms].

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SMART 116 254 139 SM00046 none Diacylglycerol kinase catalytic domain (presumed) IPR001206
PANTHER 472 491 20 PTHR12358:SF31 none none none
PANTHER 104 456 353 PTHR12358:SF31 none none none
SUPERFAMILY 113 306 194 SSF111331 none none IPR016064
SUPERFAMILY 358 469 112 SSF111331 none none IPR016064
Pfam 116 247 132 PF00781 none Diacylglycerol kinase catalytic domain IPR001206
PANTHER 472 491 20 PTHR12358 none none none
PANTHER 104 456 353 PTHR12358 none none none
ProSiteProfiles 112 254 143 PS50146 none DAG-kinase catalytic (DAGKc) domain profile. IPR001206

0 Localization

7 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2004_QTL5_peak_Bud_burst_A4 Qrob_Chr10 10 s_1C8OKQ_688 v_12844_707 25,6 13,9 39,9 lod 2,7 6,1
Bourran2_2002_QTL13_peak_Bud_burst_3P Qrob_Chr10 10 s_1B1AG7_637 s_1A3A1N_709 19,44 0 49,44 lod 3 5,6
Bourran2_2002_QTL15_peak_Bud_burst_A4 Qrob_Chr10 10 v_7579_71 s_1ATZMJ_189 23,94 0 43,64 lod 3,7 5,4
Bourran2_2014_vSeqBC_3P Qrob_Chr10 10 s_1A6CK6_610 v_7092_29 4,28 0 23,27 lod 2,8619 7
Bourran2_2014_vSeqBC_A4 Qrob_Chr10 10 s_1BAM4E_1326 s_1C0HD0_1012 36,88 7,71 46,03 lod 2,6164 7,3
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
PM_1999_QTL16_peak_Bud_burst_3P Qrob_Chr10 10 s_1B6YNI_505 s_1A1ZO_1322 7,48 0 31,48 lod 4 7,1

0 Targeting