Protein : Qrob_P0492700.2 Q. robur

Protein Identifier  ? Qrob_P0492700.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) K11518 - mitochondrial import receptor subunit TOM40 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 164  
Kegg Orthology  K11518

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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0005741 mitochondrial outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.

25 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103322524 6 163 + 158 none 50.64 312 90.51 9e-102 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|pper:PRUPE_ppa008962mg 6 163 + 158 none 50.64 312 90.51 9e-102 hypothetical protein
blastp_kegg lcl|sly:101254390 6 163 + 158 none 50.32 314 89.24 1e-100 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|sot:102588205 6 163 + 158 none 50.32 314 89.24 2e-100 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|sot:102587266 6 163 + 158 none 50.64 312 88.61 2e-100 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|pxb:103932065 6 163 + 158 none 50.64 312 88.61 2e-100 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|tcc:TCM_007667 6 162 + 157 none 50.16 313 88.54 4e-100 Translocase of the outer mitochondrial membrane 40
blastp_kegg lcl|vvi:100268104 6 163 + 158 none 51.13 309 89.24 1e-99 mitochondrial import receptor subunit TOM40 homolog 1-like
blastp_kegg lcl|sly:101262530 6 163 + 158 none 50.64 312 87.34 1e-99 mitochondrial import receptor subunit TOM40-1-like
blastp_kegg lcl|mdm:103449844 6 163 + 158 none 50.64 312 87.97 2e-99 mitochondrial import receptor subunit TOM40-1-like
blastp_uniprot_sprot sp|Q9LHE5|TO401_ARATH 7 162 + 156 none 50.49 309 77.56 1e-84 Mitochondrial import receptor subunit TOM40-1 OS Arabidopsis thaliana GN TOM40-1 PE 1 SV 3
blastp_uniprot_sprot sp|Q9SX55|TO402_ARATH 6 159 + 154 none 49.68 310 64.29 1e-70 Probable mitochondrial import receptor subunit TOM40-2 OS Arabidopsis thaliana GN TOM40-2 PE 2 SV 3
blastp_uniprot_sprot sp|Q9CZR3|TM40L_MOUSE 6 162 + 157 Gaps:18 54.22 308 35.33 4e-19 Mitochondrial import receptor subunit TOM40B OS Mus musculus GN Tomm40l PE 2 SV 1
blastp_uniprot_sprot sp|A4F267|TM40L_RAT 6 162 + 157 Gaps:18 54.22 308 35.33 4e-19 Mitochondrial import receptor subunit TOM40B OS Rattus norvegicus GN Tomm40l PE 1 SV 1
blastp_uniprot_sprot sp|A6QR22|TM40L_BOVIN 6 162 + 157 Gaps:18 54.22 308 34.73 1e-18 Mitochondrial import receptor subunit TOM40B OS Bos taurus GN TOMM40L PE 2 SV 1
blastp_uniprot_sprot sp|Q969M1|TM40L_HUMAN 6 162 + 157 Gaps:18 54.22 308 34.73 1e-18 Mitochondrial import receptor subunit TOM40B OS Homo sapiens GN TOMM40L PE 2 SV 1
blastp_uniprot_sprot sp|Q7ZTM6|TOM40_XENLA 6 162 + 157 Gaps:18 49.70 336 32.93 3e-18 Mitochondrial import receptor subunit TOM40 homolog OS Xenopus laevis GN tomm40 PE 2 SV 1
blastp_uniprot_sprot sp|Q6P825|TOM40_XENTR 6 162 + 157 Gaps:18 49.70 336 31.74 7e-18 Mitochondrial import receptor subunit TOM40 homolog OS Xenopus tropicalis GN tomm40 PE 2 SV 1
blastp_uniprot_sprot sp|P24391|TOM40_NEUCR 18 161 + 144 Gaps:17 46.13 349 29.81 2e-15 Mitochondrial import receptor subunit tom40 OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) GN tom40 PE 1 SV 1
blastp_uniprot_sprot sp|O96008|TOM40_HUMAN 6 162 + 157 Gaps:18 46.26 361 31.74 3e-15 Mitochondrial import receptor subunit TOM40 homolog OS Homo sapiens GN TOMM40 PE 1 SV 1
rpsblast_cdd gnl|CDD|132766 6 162 + 157 Gaps:8 59.14 279 44.24 2e-49 cd07305 Porin3_Tom40 Translocase of outer mitochondrial membrane 40 (Tom40). Tom40 forms a channel in the mitochondrial outer membrane with a pore about 1.5 to 2.5 nanometers wide. It functions as a transport channel for unfolded protein chains and forms a complex with Tom5 Tom6 Tom7 and Tom22. The primary receptors Tom20 and Tom70 recruit the unfolded precursor protein from the mitochondrial-import stimulating factor (MSF) or cytosolic Hsc70. The precursor passes through the Tom40 channel and through another channel in the inner membrane formed by Tim23 to be finally translocated into the mitochondrial matrix. The process depends on a proton motive force across the inner membrane and requires a contact site where the outer and inner membranes come close. Tom40 is also involved in inserting outer membrane proteins into the membrane most likely not via a lateral opening in the pore but by transfering precursor proteins to an outer membrane sorting and assembly machinery.
rpsblast_cdd gnl|CDD|201807 6 156 + 151 Gaps:17 58.09 272 31.65 9e-32 pfam01459 Porin_3 Eukaryotic porin.
rpsblast_cdd gnl|CDD|132765 4 162 + 159 Gaps:3 59.12 274 16.05 4e-14 cd07303 Porin3 Eukaryotic porin family that forms channels in the mitochondrial outer membrane. The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.
rpsblast_cdd gnl|CDD|132767 54 159 + 106 Gaps:4 39.86 276 20.91 5e-07 cd07306 Porin3_VDAC Voltage-dependent anion channel of the outer mitochondrial membrane. The voltage-dependent anion channel (VDAC) regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane which is highly permeable to small molecules. VDAC is the most abundant protein in the outer membrane and membrane potentials can toggle VDAC between open or high-conducting and closed or low-conducting forms. VDAC binds to and is regulated in part by hexokinase an interaction that renders mitochondria less susceptible to pro-apoptotic signals most likely by intefering with VDAC's capability to respond to Bcl-2 family proteins. While VDAC appears to play a key role in mitochondrially induced cell death a proposed involvement in forming the mitochondrial permeability transition pore which is characteristic for damaged mitochondria and apoptosis has been challenged by more recent studies.
rpsblast_kog gnl|CDD|38506 6 162 + 157 Gaps:7 51.95 308 39.38 2e-38 KOG3296 KOG3296 KOG3296 Translocase of outer mitochondrial membrane complex subunit TOM40 [Intracellular trafficking secretion and vesicular transport].

4 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 5 163 159 PTHR10802:SF2 none none none
Pfam 6 156 151 PF01459 none Eukaryotic porin IPR027246
PANTHER 5 163 159 PTHR10802 none none none
Gene3D 20 162 143 G3DSA:2.40.160.10 none none IPR023614

0 Localization

3 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2002_QTL17_peak_Bud_burst_A4 Qrob_Chr12 12 s_1CTJ3J_556 s_1CTJ3J_556 0 0 25 lod 2,9 6
Bourran2_2014_nSeqBC_3P Qrob_Chr12 12 s_1EO8V5_710 s_1A2VMU_355 11,04 0 32,58 lod 1,7196 4,7

0 Targeting