Protein : Qrob_P0481850.2 Q. robur

Protein Identifier  ? Qrob_P0481850.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=3) 2.7.7.13 - Mannose-1-phosphate guanylyltransferase. Code Enzyme  EC:2.7.7.13
Gene Prediction Quality  validated Protein length 

Sequence

Length: 173  
Kegg Orthology  K00966

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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0016779 nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant.

36 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pop:POPTR_0010s20620g 2 160 + 159 none 44.04 361 91.19 1e-98 POPTRDRAFT_659626 cytokinesis defective 1 family protein
blastp_kegg lcl|pxb:103942926 1 159 + 159 none 44.04 361 89.94 7e-97 mannose-1-phosphate guanylyltransferase 1
blastp_kegg lcl|mdm:103435383 1 159 + 159 none 44.04 361 89.94 7e-97 mannose-1-phosphate guanylyltransferase 1
blastp_kegg lcl|pop:POPTR_0008s06050g 1 160 + 160 none 44.32 361 88.75 3e-96 POPTRDRAFT_656143 cytokinesis defective 1 family protein
blastp_kegg lcl|cam:101504009 1 160 + 160 none 44.32 361 89.38 8e-96 mannose-1-phosphate guanylyltransferase 1-like
blastp_kegg lcl|pmum:103332527 1 159 + 159 none 44.04 361 89.31 9e-96 mannose-1-phosphate guanylyltransferase 1
blastp_kegg lcl|pper:PRUPE_ppa007618mg 1 159 + 159 none 44.04 361 89.31 9e-96 hypothetical protein
blastp_kegg lcl|mtr:MTR_5g080770 1 160 + 160 none 44.32 361 89.38 2e-95 Mannose-1-phosphate guanyltransferase
blastp_kegg lcl|sot:102577820 1 159 + 159 none 44.04 361 87.42 4e-95 GMP GDP-mannose pyrophosphorylase
blastp_kegg lcl|tcc:TCM_042692 1 159 + 159 none 44.04 361 87.42 5e-95 Glucose-1-phosphate adenylyltransferase family protein isoform 1
blastp_pdb 2ggq_A 3 144 + 142 Gaps:14 36.91 401 30.41 1e-09 mol:protein length:401 401aa long hypothetical glucose-1-phosphate t
blastp_pdb 2ggo_A 3 144 + 142 Gaps:14 36.91 401 30.41 1e-09 mol:protein length:401 401aa long hypothetical glucose-1-phosphate t
blastp_pdb 1wvc_A 4 81 + 78 Gaps:3 30.50 259 41.77 5e-09 mol:protein length:259 Glucose-1-phosphate cytidylyltransferase
blastp_pdb 1tzf_A 4 81 + 78 Gaps:3 30.50 259 41.77 5e-09 mol:protein length:259 Glucose-1-phosphate cytidylyltransferase
blastp_uniprot_sprot sp|O22287|GMPP1_ARATH 1 160 + 160 none 44.32 361 86.88 6e-96 Mannose-1-phosphate guanylyltransferase 1 OS Arabidopsis thaliana GN CYT1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9M2S0|GMPP2_ARATH 1 160 + 160 none 43.96 364 81.88 4e-92 Probable mannose-1-phosphate guanylyltransferase 2 OS Arabidopsis thaliana GN At3g55590 PE 2 SV 1
blastp_uniprot_sprot sp|Q6Z9A3|GMPP3_ORYSJ 1 159 + 159 none 44.04 361 83.02 1e-91 Probable mannose-1-phosphate guanylyltransferase 3 OS Oryza sativa subsp. japonica GN Os08g0237200 PE 2 SV 1
blastp_uniprot_sprot sp|Q84JH5|GMPP1_ORYSJ 1 159 + 159 none 44.04 361 80.50 5e-90 Probable mannose-1-phosphate guanylyltransferase 1 OS Oryza sativa subsp. japonica GN Os03g0268400 PE 2 SV 1
blastp_uniprot_sprot sp|Q941T9|GMPP2_ORYSJ 1 159 + 159 none 44.04 361 81.76 7e-90 Probable mannose-1-phosphate guanylyltransferase 2 OS Oryza sativa subsp. japonica GN Os01g0847200 PE 2 SV 1
blastp_uniprot_sprot sp|Q8H1Q7|GMPP3_ARATH 2 159 + 158 none 47.73 331 74.05 6e-80 Probable mannose-1-phosphate guanylyltransferase 3 OS Arabidopsis thaliana GN At4g30570 PE 2 SV 1
blastp_uniprot_sprot sp|Q68EY9|GMPBA_XENLA 2 159 + 158 none 43.89 360 56.33 3e-62 Mannose-1-phosphate guanyltransferase beta-A OS Xenopus laevis GN gmppb-a PE 2 SV 1
blastp_uniprot_sprot sp|Q68EQ1|GMPPB_XENTR 2 159 + 158 none 43.89 360 55.06 5e-61 Mannose-1-phosphate guanyltransferase beta OS Xenopus tropicalis GN gmppb PE 2 SV 1
blastp_uniprot_sprot sp|Q9Y5P6|GMPPB_HUMAN 2 157 + 156 none 43.33 360 57.05 2e-60 Mannose-1-phosphate guanyltransferase beta OS Homo sapiens GN GMPPB PE 1 SV 2
blastp_uniprot_sprot sp|P0C5I2|GMPPB_PIG 2 157 + 156 none 43.33 360 56.41 6e-60 Mannose-1-phosphate guanyltransferase beta OS Sus scrofa GN GMPPB PE 1 SV 1
rpsblast_cdd gnl|CDD|133047 1 85 + 85 none 36.48 233 70.59 4e-40 cd06425 M1P_guanylylT_B_like_N N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins. GDP-mannose pyrophosphorylase (GTP: alpha-d-mannose-1-phosphate guanyltransferase) catalyzes the formation of GDP-d-mannose from GTP and alpha-d-mannose-1-Phosphate. It contains an N-terminal catalytic domain and a C-terminal Lefthanded-beta-Helix fold domain. GDP-d-mannose is the activated form of mannose for formation of cell wall lipoarabinomannan and various mannose-containing glycolipids and polysaccharides. The function of GDP-mannose pyrophosphorylase is essential for cell wall integrity morphogenesis and viability. Repression of GDP-mannose pyrophosphorylase in yeast leads to phenotypes such as cell lysis defective cell wall and failure of polarized growth and cell separation.
rpsblast_cdd gnl|CDD|31401 2 158 + 157 Gaps:10 46.65 358 33.53 5e-28 COG1208 GCD1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis outer membrane / Translation ribosomal structure and biogenesis].
rpsblast_cdd gnl|CDD|188507 6 149 + 144 Gaps:23 42.49 393 29.34 2e-16 TIGR03992 Arch_glmU UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. The MJ_1101 protein from Methanococcus jannaschii has been characterized as the GlmU enzyme catalyzing the final two steps of UDP-GlcNAc biosynthesis. Many of the genes identified by this model are in proximity to the GlmS and GlmM genes and are also presumed to be GlmU. However some archaeal genomes contain multiple closely-related homologs from this family and it is not clear what the substrate specificity is for each of them.
rpsblast_cdd gnl|CDD|133024 6 72 + 67 Gaps:3 32.26 217 37.14 2e-14 cd04181 NTP_transferase NTP_transferases catalyze the transfer of nucleotides onto phosphosugars. Nucleotidyltransferases transfer nucleotides onto phosphosugars. The enzyme family includes Alpha-D-Glucose-1-Phosphate Cytidylyltransferase Mannose-1-phosphate guanyltransferase and Glucose-1-phosphate thymidylyltransferase. The products are activated sugars that are precursors for synthesis of lipopolysaccharide glycolipids and polysaccharides.
rpsblast_cdd gnl|CDD|133065 6 77 + 72 none 32.29 223 36.11 7e-10 cd06915 NTP_transferase_WcbM_like WcbM_like is a subfamily of nucleotidyl transferases. WcbM protein of Burkholderia mallei is involved in the biosynthesis export or translocation of capsule. It is a subfamily of nucleotidyl transferases that transfer nucleotides onto phosphosugars.
rpsblast_cdd gnl|CDD|100062 107 159 + 53 none 66.25 80 35.85 1e-09 cd05824 LbH_M1P_guanylylT_C Mannose-1-phosphate guanylyltransferase C-terminal Left-handed parallel beta helix (LbH) domain: Mannose-1-phosphate guanylyltransferase is also known as GDP-mannose pyrophosphorylase. It catalyzes the synthesis of GDP-mannose from GTP and mannose-1-phosphate and is involved in the maintenance of cell wall integrity and glycosylation. Similar to ADP-glucose pyrophosphorylase it contains an N-terminal catalytic domain that resembles a dinucleotide-binding Rossmann fold and a C-terminal LbH fold domain presumably with 4 turns each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes showing acyltransferase activity..

10 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 152 152 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Gene3D 95 157 63 G3DSA:2.160.10.10 none none none
Phobius 170 172 3 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 5 81 77 G3DSA:3.90.550.10 none none IPR029044
Pfam 4 80 77 PF00483 "Reactome:REACT_17015" Nucleotidyl transferase IPR005835
Phobius 153 169 17 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 1 159 159 PTHR22572 none none none
Pfam 106 138 33 PF00132 none Bacterial transferase hexapeptide (six repeats) IPR001451
SUPERFAMILY 4 151 148 SSF53448 none none IPR029044
PANTHER 1 159 159 PTHR22572:SF75 none none none

1 Localization

Analysis Start End Length
TMHMM 153 170 17

0 Qtllist

0 Targeting