Protein : Qrob_P0478060.2 Q. robur
Protein Identifier  ? Qrob_P0478060.2 Organism . Name  Quercus robur
Score  99.0 Score Type  egn
Protein Description  (M=1) PTHR22999:SF19 - PHOX (PX) DOMAIN-CONTAINING PROTEIN (PTHR22999:SF19) Gene Prediction Quality  validated
Protein length 

Sequence

Length: 1101  
Kegg Orthology  K17925
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Protein Sequence Displayer

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0 Synonyms

1 GO Terms

Identifier Name Description
GO:0035091 phosphatidylinositol binding Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103327935 1 1067 + 1067 Gaps:39 96.09 1124 72.22 0.0 uncharacterized LOC103327935
blastp_kegg lcl|pper:PRUPE_ppa000505mg 1 1067 + 1067 Gaps:39 96.09 1124 71.67 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0001s18360g 1 1067 + 1067 Gaps:43 96.15 1144 66.82 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_028745 7 1067 + 1061 Gaps:32 95.79 1139 69.57 0.0 Phox-associated domain Phox-like Sorting nexin isoform 1
blastp_kegg lcl|pxb:103944871 1 1067 + 1067 Gaps:59 96.03 1108 70.68 0.0 uncharacterized LOC103944871
blastp_kegg lcl|mdm:103405465 1 1067 + 1067 Gaps:55 96.04 1112 69.57 0.0 uncharacterized LOC103405465
blastp_kegg lcl|pxb:103937776 1 1067 + 1067 Gaps:55 96.04 1112 69.94 0.0 uncharacterized LOC103937776
blastp_kegg lcl|cic:CICLE_v10024750mg 1 1067 + 1067 Gaps:48 96.07 1121 69.36 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0003s05200g 1 1067 + 1067 Gaps:55 95.85 1156 65.79 0.0 hypothetical protein
blastp_kegg lcl|fve:101312561 3 1097 + 1095 Gaps:68 98.72 1095 67.44 0.0 uncharacterized protein LOC101312561
blastp_pdb 1xte_A 696 788 + 93 Gaps:2 60.39 154 33.33 3e-08 mol:protein length:154 Serine/threonine-protein kinase Sgk3
blastp_pdb 1xtn_B 692 788 + 97 Gaps:2 80.83 120 31.96 5e-08 mol:protein length:120 Serine/threonine-protein kinase Sgk3
blastp_pdb 1xtn_A 692 788 + 97 Gaps:2 80.83 120 31.96 5e-08 mol:protein length:120 Serine/threonine-protein kinase Sgk3
blastp_uniprot_sprot sp|Q5R6Q7|SNX16_PONAB 685 787 + 103 Gaps:2 29.94 344 32.04 2e-08 Sorting nexin-16 OS Pongo abelii GN SNX16 PE 2 SV 1
blastp_uniprot_sprot sp|P57768|SNX16_HUMAN 685 787 + 103 Gaps:2 29.94 344 32.04 2e-08 Sorting nexin-16 OS Homo sapiens GN SNX16 PE 1 SV 2
blastp_uniprot_sprot sp|Q8C080|SNX16_MOUSE 685 787 + 103 Gaps:2 29.94 344 32.04 3e-08 Sorting nexin-16 OS Mus musculus GN Snx16 PE 1 SV 2
blastp_uniprot_sprot sp|P57769|SNX16_RAT 685 787 + 103 Gaps:2 29.94 344 32.04 3e-08 Sorting nexin-16 OS Rattus norvegicus GN Snx16 PE 1 SV 2
blastp_uniprot_sprot sp|Q9ERE3|SGK3_MOUSE 696 788 + 93 Gaps:2 18.75 496 33.33 1e-06 Serine/threonine-protein kinase Sgk3 OS Mus musculus GN Sgk3 PE 1 SV 1
blastp_uniprot_sprot sp|Q8R4V0|SGK3_RAT 696 788 + 93 Gaps:2 18.75 496 33.33 1e-06 Serine/threonine-protein kinase Sgk3 OS Rattus norvegicus GN Sgk3 PE 1 SV 2
blastp_uniprot_sprot sp|Q5R7A7|SGK3_PONAB 696 788 + 93 Gaps:2 18.75 496 33.33 1e-06 Serine/threonine-protein kinase Sgk3 OS Pongo abelii GN SGK3 PE 2 SV 1
blastp_uniprot_sprot sp|Q96BR1|SGK3_HUMAN 696 788 + 93 Gaps:2 18.75 496 33.33 1e-06 Serine/threonine-protein kinase Sgk3 OS Homo sapiens GN SGK3 PE 1 SV 1
blastp_uniprot_sprot sp|Q6PHS6|SNX13_MOUSE 680 993 + 314 Gaps:53 30.83 957 23.39 8e-06 Sorting nexin-13 OS Mus musculus GN Snx13 PE 2 SV 1
rpsblast_cdd gnl|CDD|132782 681 785 + 105 none 98.13 107 66.67 9e-44 cd06872 PX_SNX19_like_plant The phosphoinositide binding Phox Homology domain of uncharacterized SNX19-like plant proteins. The PX domain is a phosphoinositide (PI) binding module involved in targeting proteins to PI-enriched membranes. Members in this subfamily are uncharacterized plant proteins containing an N-terminal PXA domain a central PX domain and a C-terminal domain that is conserved in some sorting nexins (SNXs). This is the same domain architecture found in SNX19. SNX13 and SNX14 also contain these three domains but also contain a regulator of G protein signaling (RGS) domain in between the PXA and PX domains. SNXs make up the largest group among PX domain containing proteins. They are involved in regulating membrane traffic and protein sorting in the endosomal system. The PX domain of SNXs binds PIs and targets the protein to PI-enriched membranes. SNXs differ from each other in PI-binding specificity and affinity and the presence of other protein-protein interaction domains which help determine subcellular localization and specific function in the endocytic pathway. In addition to protein-lipid interaction the PX domain may also be involved in protein-protein interaction.
rpsblast_cdd gnl|CDD|202146 104 283 + 180 Gaps:3 98.35 182 37.99 1e-39 pfam02194 PXA PXA domain. This domain is associated with PX domains pfam00787.
rpsblast_cdd gnl|CDD|132768 683 785 + 103 Gaps:3 98.11 106 38.46 6e-19 cd06093 PX_domain The Phox Homology domain a phosphoinositide binding module. The PX domain is a phosphoinositide (PI) binding module involved in targeting proteins to membranes. Proteins containing PX domains interact with PIs and have been implicated in highly diverse functions such as cell signaling vesicular trafficking protein sorting lipid modification cell polarity and division activation of T and B cells and cell survival. Many members of this superfamily bind phosphatidylinositol-3-phosphate (PI3P) but in some cases other PIs such as PI4P or PI(3 4)P2 among others are the preferred substrates. In addition to protein-lipid interaction the PX domain may also be involved in protein-protein interaction as in the cases of p40phox p47phox and some sorting nexins (SNXs). The PX domain is conserved from yeast to humans and is found in more than 100 proteins. The majority of PX domain-containing proteins are SNXs which play important roles in endosomal sorting.
rpsblast_cdd gnl|CDD|201443 695 787 + 93 Gaps:4 87.16 109 38.95 4e-17 pfam00787 PX PX domain. PX domains bind to phosphoinositides.
rpsblast_cdd gnl|CDD|197645 692 785 + 94 Gaps:6 95.24 105 31.00 1e-11 smart00312 PX PhoX homologous domain present in p47phox and p40phox. Eukaryotic domain of unknown function present in phox proteins PLD isoforms a PI3K isoform.
rpsblast_cdd gnl|CDD|128608 100 279 + 180 Gaps:15 94.89 176 20.36 5e-11 smart00313 PXA Domain associated with PX domains. unpubl. observations.
rpsblast_cdd gnl|CDD|132809 681 787 + 107 Gaps:2 97.27 110 29.91 3e-10 cd07276 PX_SNX16 The phosphoinositide binding Phox Homology domain of Sorting Nexin 16. The PX domain is a phosphoinositide (PI) binding module present in many proteins with diverse functions. Sorting nexins (SNXs) make up the largest group among PX domain containing proteins. They are involved in regulating membrane traffic and protein sorting in the endosomal system. The PX domain of SNXs binds PIs and targets the protein to PI-enriched membranes. SNXs differ from each other in PI-binding specificity and affinity and the presence of other protein-protein interaction domains which help determine subcellular localization and specific function in the endocytic pathway. SNX16 contains a central PX domain followed by a coiled-coil region. SNX16 is localized in early and recycling endosomes through the binding of its PX domain to phosphatidylinositol-3-phosphate (PI3P). It plays a role in epidermal growth factor (EGF) signaling by regulating EGF receptor membrane trafficking.
rpsblast_cdd gnl|CDD|149621 931 1067 + 137 Gaps:32 96.33 109 25.71 4e-10 pfam08628 Nexin_C Sorting nexin C terminal. This region is found a the C terminal of proteins belonging to the sorting nexin family. It is found on proteins which also contain pfam00787.

22 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 104 283 180 PF02194 none PXA domain IPR003114
ProSiteProfiles 679 791 113 PS50195 none PX domain profile. IPR001683
ProSiteProfiles 104 287 184 PS51207 none PXA domain profile. IPR003114
PANTHER 1 302 302 PTHR22999:SF19 none none none
Pfam 692 787 96 PF00787 none PX domain IPR001683
PANTHER 910 1067 158 PTHR22999 none none none
PANTHER 665 873 209 PTHR22999 none none none
SMART 108 287 180 SM00313 none Domain associated with PX domains IPR013996
Gene3D 676 789 114 G3DSA:3.30.1520.10 none none IPR001683
Phobius 1 20 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 43 60 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 21 37 17 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 61 1100 1040 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 392 475 84 PTHR22999:SF19 none none none
PANTHER 665 873 209 PTHR22999:SF19 none none none
Phobius 38 42 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
SUPERFAMILY 680 788 109 SSF64268 none none IPR001683
SMART 677 787 111 SM00312 none PhoX homologous domain, present in p47phox and p40phox. IPR001683
PANTHER 392 475 84 PTHR22999 none none none
PANTHER 910 1067 158 PTHR22999:SF19 none none none
Pfam 931 1067 137 PF08628 none Sorting nexin C terminal IPR013937
PANTHER 1 302 302 PTHR22999 none none none

1 Localization

Analysis Start End Length
TMHMM 22 44 22

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting