Protein : Qrob_P0435950.2 Q. robur
Protein Identifier  ? Qrob_P0435950.2 Organism . Name  Quercus robur
Score  2.0 Score Type  egn
Protein Description  (M=1) K03348 - anaphase-promoting complex subunit 1 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 1946  
Kegg Orthology  K03348
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0 Synonyms

1 GO Terms

Identifier Name Description
GO:0005680 anaphase-promoting complex A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.

19 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pmum:103332797 2 1944 + 1943 Gaps:66 99.78 1822 79.37 0.0 anaphase-promoting complex subunit 1
blastp_kegg lcl|pxb:103958621 3 1944 + 1942 Gaps:46 99.56 1831 77.51 0.0 anaphase-promoting complex subunit 1
blastp_kegg lcl|mdm:103432840 3 1944 + 1942 Gaps:49 99.56 1828 77.64 0.0 anaphase-promoting complex subunit 1
blastp_kegg lcl|cit:102625759 1 1944 + 1944 Gaps:67 99.73 1823 77.78 0.0 anaphase-promoting complex subunit 1-like
blastp_kegg lcl|tcc:TCM_042482 1 1943 + 1943 Gaps:50 99.84 1823 77.75 0.0 E3 ubiquitin ligase isoform 1
blastp_kegg lcl|gmx:100818647 1 1944 + 1944 Gaps:87 100.00 1806 74.36 0.0 anaphase-promoting complex subunit 1-like
blastp_kegg lcl|cam:101499129 1 1944 + 1944 Gaps:113 100.00 1780 74.94 0.0 anaphase-promoting complex subunit 1-like
blastp_kegg lcl|pvu:PHAVU_008G222900g 1 1944 + 1944 Gaps:82 100.00 1805 74.18 0.0 hypothetical protein
blastp_kegg lcl|gmx:100778607 1 1944 + 1944 Gaps:98 100.00 1812 74.28 0.0 anaphase-promoting complex subunit 1-like
blastp_kegg lcl|cmo:103502874 1 1943 + 1943 Gaps:52 99.84 1823 73.57 0.0 anaphase-promoting complex subunit 1
blastp_uniprot_sprot sp|Q9FFF9|APC1_ARATH 1 1941 + 1941 Gaps:131 99.64 1678 65.43 0.0 Anaphase-promoting complex subunit 1 OS Arabidopsis thaliana GN APC1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9H1A4|APC1_HUMAN 67 1928 + 1862 Gaps:274 85.03 1944 33.64 0.0 Anaphase-promoting complex subunit 1 OS Homo sapiens GN ANAPC1 PE 1 SV 1
blastp_uniprot_sprot sp|P53995|APC1_MOUSE 45 1934 + 1890 Gaps:271 86.93 1944 32.37 0.0 Anaphase-promoting complex subunit 1 OS Mus musculus GN Anapc1 PE 2 SV 2
blastp_uniprot_sprot sp|Q54NC6|APC1_DICDI 735 1821 + 1087 Gaps:185 48.88 2269 32.46 3e-134 Anaphase-promoting complex subunit 1 OS Dictyostelium discoideum GN anapc1 PE 3 SV 1
blastp_uniprot_sprot sp|P24686|BIME_EMENI 717 1753 + 1037 Gaps:160 46.30 2067 34.38 6e-109 Negative regulator of mitosis OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN bimE PE 2 SV 2
blastp_uniprot_sprot sp|Q9URV2|APC1_SCHPO 724 1685 + 962 Gaps:129 59.05 1458 33.10 2e-99 Anaphase-promoting complex subunit 1 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN cut4 PE 1 SV 1
blastp_uniprot_sprot sp|P53886|APC1_YEAST 1017 1712 + 696 Gaps:90 38.27 1748 29.60 9e-36 Anaphase-promoting complex subunit 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN APC1 PE 1 SV 2
rpsblast_cdd gnl|CDD|205112 110 227 + 118 Gaps:36 98.80 83 28.05 2e-11 pfam12859 Apc1 Anaphase-promoting complex subunit 1. Apc1 is the largest of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. Infection of human fibroblasts with human cytomegalovirus (HCMV) leads to cell cycle dysregulation which is associated with the inactivation of the anaphase-promoting complex.
rpsblast_kog gnl|CDD|37069 113 1877 + 1765 Gaps:174 99.47 1496 37.84 0.0 KOG1858 KOG1858 KOG1858 Anaphase-promoting complex (APC) subunit 1 (meiotic check point regulator/Tsg24) [Cell cycle control cell division chromosome partitioning Posttranslational modification protein turnover chaperones].

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 1513 1513 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1572 1945 374 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 201 313 113 PTHR12827 none none IPR024990
PANTHER 1753 1943 191 PTHR12827 none none IPR024990
PANTHER 48 169 122 PTHR12827 none none IPR024990
PANTHER 341 1737 1397 PTHR12827 none none IPR024990
Phobius 1552 1571 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 1532 1551 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 1514 1531 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 1454 1486 33 PF01851 "Reactome:REACT_11045","Reactome:REACT_13","Reactome:REACT_13635","Reactome:REACT_152","Reactome:REACT_1538","Reactome:REACT_383","Reactome:REACT_578","Reactome:REACT_6185","Reactome:REACT_6850" Proteasome/cyclosome repeat IPR002015
Pfam 110 225 116 PF12859 none Anaphase-promoting complex subunit 1 IPR024990

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6

0 Targeting