Protein : Qrob_P0410710.2 Q. robur
Protein Identifier  ? Qrob_P0410710.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=1) K10742 - DNA replication ATP-dependent helicase Dna2 [EC:3.6.4.12] Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 1292  
Kegg Orthology  K10742
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0017108 5'-flap endonuclease activity Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.
GO:0033567 DNA replication, Okazaki fragment processing The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.
GO:0043142 single-stranded DNA-dependent ATPase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|vvi:100247844 89 1291 + 1203 Gaps:67 86.51 1438 71.95 0.0 DNA2-like helicase-like
blastp_kegg lcl|pmum:103331439 1 1291 + 1291 Gaps:105 100.00 1366 68.23 0.0 DNA replication ATP-dependent helicase/nuclease DNA2
blastp_kegg lcl|pop:POPTR_0014s17840g 111 1291 + 1181 Gaps:111 99.92 1189 74.41 0.0 POPTRDRAFT_247435 DNA replication helicase family protein
blastp_kegg lcl|pxb:103929759 1 1289 + 1289 Gaps:159 99.72 1408 65.17 0.0 DNA replication ATP-dependent helicase/nuclease DNA2
blastp_kegg lcl|tcc:TCM_042345 1 1291 + 1291 Gaps:143 99.86 1384 66.50 0.0 DNA replication helicase dna2 isoform 2
blastp_kegg lcl|cit:102608255 1 1291 + 1291 Gaps:170 100.00 1377 65.80 0.0 DNA replication ATP-dependent helicase/nuclease DNA2-like
blastp_kegg lcl|pper:PRUPE_ppa022505mg 111 1291 + 1181 Gaps:73 99.75 1205 72.38 0.0 hypothetical protein
blastp_kegg lcl|fve:101299140 1 1291 + 1291 Gaps:111 100.00 1358 66.57 0.0 DNA replication ATP-dependent helicase/nuclease DNA2-like
blastp_kegg lcl|mdm:103438958 1 1239 + 1239 Gaps:133 98.00 1351 65.71 0.0 DNA replication ATP-dependent helicase/nuclease DNA2
blastp_kegg lcl|cmo:103483415 1 1288 + 1288 Gaps:145 100.00 1379 62.58 0.0 DNA replication ATP-dependent helicase/nuclease DNA2
blastp_pdb 2gk7_A 872 1278 + 407 Gaps:61 69.87 624 30.73 3e-37 mol:protein length:624 Regulator of nonsense transcripts 1
blastp_pdb 2gk6_B 872 1278 + 407 Gaps:61 69.87 624 30.73 3e-37 mol:protein length:624 Regulator of nonsense transcripts 1
blastp_pdb 2gk6_A 872 1278 + 407 Gaps:61 69.87 624 30.73 3e-37 mol:protein length:624 Regulator of nonsense transcripts 1
blastp_pdb 2gjk_A 872 1278 + 407 Gaps:61 69.87 624 30.73 3e-37 mol:protein length:624 Regulator of nonsense transcripts 1
blastp_pdb 2xzp_A 872 1278 + 407 Gaps:61 69.98 623 30.73 3e-37 mol:protein length:623 REGULATOR OF NONSENSE TRANSCRIPTS 1
blastp_pdb 2xzo_A 872 1278 + 407 Gaps:61 69.98 623 30.73 3e-37 mol:protein length:623 REGULATOR OF NONSENSE TRANSCRIPTS 1
blastp_pdb 2wjy_A 872 1278 + 407 Gaps:75 54.50 800 30.50 9e-37 mol:protein length:800 REGULATOR OF NONSENSE TRANSCRIPTS 1
blastp_pdb 2wjv_B 872 1278 + 407 Gaps:75 54.50 800 30.50 9e-37 mol:protein length:800 REGULATOR OF NONSENSE TRANSCRIPTS 1
blastp_pdb 2wjv_A 872 1278 + 407 Gaps:75 54.50 800 30.50 9e-37 mol:protein length:800 REGULATOR OF NONSENSE TRANSCRIPTS 1
blastp_pdb 2xzl_A 872 1271 + 400 Gaps:63 53.24 802 29.04 1e-27 mol:protein length:802 ATP-DEPENDENT HELICASE NAM7
blastp_uniprot_sprot sp|Q8QHA5|DNA2_XENLA 353 1270 + 918 Gaps:122 90.60 1053 35.95 1e-164 DNA replication ATP-dependent helicase/nuclease DNA2 OS Xenopus laevis GN dna2 PE 1 SV 1
blastp_uniprot_sprot sp|E1BMP7|DNA2_BOVIN 353 1273 + 921 Gaps:144 90.57 1061 34.44 5e-146 DNA replication ATP-dependent helicase/nuclease DNA2 OS Bos taurus GN DNA2 PE 3 SV 3
blastp_uniprot_sprot sp|D3ZG52|DNA2_RAT 346 1270 + 925 Gaps:123 91.03 1059 34.65 1e-145 DNA replication ATP-dependent helicase/nuclease DNA2 OS Rattus norvegicus GN Dna2 PE 3 SV 1
blastp_uniprot_sprot sp|Q6ZQJ5|DNA2_MOUSE 357 1273 + 917 Gaps:135 90.21 1062 34.66 6e-145 DNA replication ATP-dependent helicase/nuclease DNA2 OS Mus musculus GN Dna2 PE 1 SV 2
blastp_uniprot_sprot sp|P51530|DNA2_HUMAN 353 1273 + 921 Gaps:138 90.66 1060 34.86 5e-144 DNA replication ATP-dependent helicase/nuclease DNA2 OS Homo sapiens GN DNA2 PE 1 SV 3
blastp_uniprot_sprot sp|Q5ZKG3|DNA2_CHICK 346 1273 + 928 Gaps:152 94.15 992 35.01 2e-141 DNA replication ATP-dependent helicase/nuclease DNA2 OS Gallus gallus GN DNA2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9URU2|DNA2_SCHPO 335 1289 + 955 Gaps:146 70.65 1397 34.04 2e-140 DNA replication ATP-dependent helicase/nuclease dna2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN dna2 PE 1 SV 2
blastp_uniprot_sprot sp|P38859|DNA2_YEAST 274 1276 + 1003 Gaps:170 71.42 1522 31.83 2e-136 DNA replication ATP-dependent helicase/nuclease DNA2 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN DNA2 PE 1 SV 1
blastp_uniprot_sprot sp|F6QXW0|DNA2_XENTR 353 1270 + 918 Gaps:141 90.55 1048 31.30 1e-108 DNA replication ATP-dependent helicase/nuclease DNA2 OS Xenopus tropicalis GN dna2 PE 3 SV 1
blastp_uniprot_sprot sp|P38935|SMBP2_HUMAN 663 1262 + 600 Gaps:121 61.73 993 28.06 1e-43 DNA-binding protein SMUBP-2 OS Homo sapiens GN IGHMBP2 PE 1 SV 3

9 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Pfam 1048 1249 202 PF13087 none AAA domain none
Pfam 872 962 91 PF13086 none AAA domain none
Pfam 972 1039 68 PF13086 none AAA domain none
Gene3D 862 1079 218 G3DSA:3.40.50.300 none none IPR027417
PANTHER 336 1278 943 PTHR10887:SF14 none none IPR026851
Pfam 341 540 200 PF08696 none DNA replication factor Dna2 IPR014808
PANTHER 336 1278 943 PTHR10887 none none none
Gene3D 1080 1248 169 G3DSA:3.40.50.300 none none IPR027417
SUPERFAMILY 871 1256 386 SSF52540 none none IPR027417

1 Localization

Analysis Start End Length
SignalP_GRAM_POSITIVE 1 10 9

7 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran1_2004_QTL4_peak_Bud_burst_3P Qrob_Chr04 4 s_1AHUWN_1101 s_1BRNG7_1618 30,55 0 47,55 lod 2,8 7,4
Bourran2_2002_QTL10_peak_Bud_burst_A4 Qrob_Chr04 4 s_1B59MJ_737 s_1BGLSD_999 15,86 0 41,66 lod 2,8 4
Bourran1_2000_QTL3_peak_Bud_burst_3P Qrob_Chr04 4 s_1A6DJQ_418 s_1A1PEC_1268 23,09 9,09 44,09 lod 2,3 6,8
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL7_d13Cf Qrob_Chr04 4 s_1B91MJ_705 s_1AHIKX_640 33.92 12,11 48,31 lod 6.1865 0.023

0 Targeting