Protein : Qrob_P0400860.2 Q. robur
Protein Identifier  ? Qrob_P0400860.2 Organism . Name  Quercus robur
Score  9.2 Score Type  egn
Protein Description  (M=3) K00507 - stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] Gene Prediction Quality  validated
Protein length 

Sequence

Length: 390  
Kegg Orthology  K00507
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0006629 lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.

25 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa006843mg 1 389 + 389 Gaps:5 99.75 393 72.19 0.0 hypothetical protein
blastp_kegg lcl|fve:101295541 1 389 + 389 Gaps:5 99.75 393 71.17 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic-like
blastp_kegg lcl|pmum:103328085 1 389 + 389 Gaps:7 99.75 395 69.54 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic
blastp_kegg lcl|pxb:103939078 1 389 + 389 Gaps:6 99.75 394 68.45 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic-like
blastp_kegg lcl|pxb:103955282 1 389 + 389 Gaps:6 99.75 394 68.19 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic
blastp_kegg lcl|mdm:103437270 1 389 + 389 Gaps:6 99.75 394 67.18 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic
blastp_kegg lcl|sly:101250586 1 389 + 389 Gaps:11 99.22 387 66.67 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic-like
blastp_kegg lcl|tcc:TCM_027193 1 388 + 388 Gaps:17 99.22 386 68.67 0.0 Fatty acid desaturase 5 isoform 1
blastp_kegg lcl|gmx:100786391 1 389 + 389 Gaps:10 98.21 390 67.89 0.0 palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic-like
blastp_kegg lcl|mtr:MTR_4g010150 1 389 + 389 Gaps:15 67.13 572 69.01 0.0 Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase
blastp_uniprot_sprot sp|Q949X0|ADS3_ARATH 95 389 + 295 Gaps:1 79.78 371 73.99 1e-166 Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase chloroplastic OS Arabidopsis thaliana GN ADS3 PE 2 SV 2
blastp_uniprot_sprot sp|O65797|ADS1_ARATH 98 389 + 292 Gaps:1 95.41 305 59.11 5e-131 Delta-9 acyl-lipid desaturase 1 OS Arabidopsis thaliana GN ADS1 PE 2 SV 1
blastp_uniprot_sprot sp|Q9SID2|ADS2_ARATH 110 389 + 280 Gaps:1 90.88 307 60.57 4e-125 Delta-9 acyl-lipid desaturase 2 OS Arabidopsis thaliana GN ADS2 PE 2 SV 2
blastp_uniprot_sprot sp|Q9LVZ3|ADS32_ARATH 83 389 + 307 Gaps:2 84.49 361 56.72 8e-125 Probable lipid desaturase ADS3.2 chloroplastic OS Arabidopsis thaliana GN ADS3.2 PE 2 SV 3
blastp_uniprot_sprot sp|Q9LND8|ADSL2_ARATH 107 389 + 283 Gaps:1 94.31 299 58.51 3e-120 Delta-9 desaturase-like 2 protein OS Arabidopsis thaliana GN At1g06100 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LND9|ADSL1_ARATH 106 389 + 284 Gaps:1 94.65 299 57.95 2e-118 Delta-9 desaturase-like 1 protein OS Arabidopsis thaliana GN At1g06090 PE 2 SV 1
blastp_uniprot_sprot sp|Q9FPD5|ADSL3_ARATH 106 389 + 284 Gaps:1 94.65 299 56.54 2e-117 Delta-9 desaturase-like 3 protein OS Arabidopsis thaliana GN At1g06120 PE 2 SV 1
blastp_uniprot_sprot sp|Q9LMI4|ADSL4_ARATH 103 389 + 287 Gaps:1 95.33 300 57.34 2e-115 Delta-9 desaturase-like 4 protein OS Arabidopsis thaliana GN At1g06350 PE 2 SV 2
blastp_uniprot_sprot sp|Q9LMI3|ADSL5_ARATH 107 389 + 283 Gaps:1 94.31 299 55.67 3e-113 Delta-9 desaturase-like 5 protein OS Arabidopsis thaliana GN At1g06360 PE 2 SV 1
blastp_uniprot_sprot sp|O94523|ACO1_SCHPO 147 384 + 238 Gaps:18 50.94 479 36.89 3e-37 Probable acyl-CoA desaturase OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN SPCC1281.06c PE 3 SV 1
rpsblast_cdd gnl|CDD|177866 106 389 + 284 Gaps:1 94.65 299 60.78 1e-121 PLN02220 PLN02220 delta-9 acyl-lipid desaturase.
rpsblast_cdd gnl|CDD|31588 117 385 + 269 Gaps:4 94.46 289 39.56 7e-63 COG1398 OLE1 Fatty-acid desaturase [Lipid metabolism].
rpsblast_cdd gnl|CDD|58171 146 377 + 232 Gaps:54 100.00 178 55.06 6e-58 cd03505 Delta9-FADS-like The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates insects higher plants and fungi. The delta-9 acyl-lipid desaturases are found in a wide range of bacteria. These enzymes play essential roles in fatty acid metabolism and the regulation of cell membrane fluidity. Acyl-CoA desaturases are the enzymes involved in the CoA-bound desaturation of fatty acids. Mammalian stearoyl-CoA delta-9 desaturase is a key enzyme in the biosynthesis of monounsaturated fatty acids and in yeast the delta-9 acyl-CoA desaturase (OLE1) reaction accounts for all de nova unsaturated fatty acid production in Saccharomyces cerevisiae. These non-heme iron-containing ER membrane-bound enzymes are part of a three-component enzyme system involving cytochrome b5 cytochrome b5 reductase and the delta-9 fatty acid desaturase. This complex catalyzes the NADH- and oxygen-dependent insertion of a cis double bond between carbons 9 and 10 of the saturated fatty acyl substrates palmitoyl (16:0)-CoA or stearoyl (18:0)-CoA yielding the monoenoic products palmitoleic (16:l) or oleic (18:l) acids respectively. In cyanobacteria the biosynthesis of unsaturated fatty acids is initiated by delta 9 acyl-lipid desaturase (DesC) which introduces the first double bond at the delta-9 position of a saturated fatty acid that has been esterified to a glycerolipid. This domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain the residues: HXXXXH HXXHH and H/QXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the rat stearoyl CoA delta-9 desaturase. Some eukaryotic (Fungi Euglenozoa Mycetozoa Rhodophyta) desaturase domains have an adjacent C-terminal cytochrome b5-like domain..
rpsblast_cdd gnl|CDD|201259 146 355 + 210 Gaps:24 92.43 251 17.67 3e-10 pfam00487 FA_desaturase Fatty acid desaturase.
rpsblast_kog gnl|CDD|36813 110 389 + 280 Gaps:10 89.72 321 47.57 1e-102 KOG1600 KOG1600 KOG1600 Fatty acid desaturase [Lipid transport and metabolism].

17 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Phobius 1 123 123 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PRINTS 334 348 15 PR00075 none Fatty acid desaturase family 1 signature IPR015876
PRINTS 146 168 23 PR00075 none Fatty acid desaturase family 1 signature IPR015876
PRINTS 206 235 30 PR00075 none Fatty acid desaturase family 1 signature IPR015876
PRINTS 291 312 22 PR00075 none Fatty acid desaturase family 1 signature IPR015876
PRINTS 169 189 21 PR00075 none Fatty acid desaturase family 1 signature IPR015876
Phobius 294 312 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 124 142 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 148 168 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 169 265 97 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Pfam 147 353 207 PF00487 none Fatty acid desaturase IPR005804
Phobius 313 389 77 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 289 293 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 104 389 286 PTHR11351 none none none
Phobius 143 147 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
PANTHER 104 389 286 PTHR11351:SF2 none none none
Phobius 266 288 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

2 Localization

Analysis Start End Length
TMHMM 266 288 22
TMHMM 146 168 22

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_rEpiBC_3P Qrob_Chr05 5 s_2GDU0O_517 s_1BT8O3_239 25,81 0 55,45 lod 2,2101 5,5

0 Targeting